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Heterogeneity is a fact of category-specific semantic deficits. so? comments on Rosazza, Imbornone, Zorzi, Farina, Chiavari, And Cappa (2003).

The Sensory/Functional Theory, until recently the received explanation of category-specific semantic deficits, has been shown to be at variance with various facts that have emerged about the nature of these deficits. In this context, Rosazza, Imbornone, Zorzi, Farina, Chiavari, and Cappa (2003: The Heterogeneity of Category-Specific Semantic Disorders: Evidence from a New Case. Neurocase, 9, 189-202.) report the case study of a patient, MA, with a purported category-specific semantic deficit for living things compared to nonliving things, and an associated modality-specific impairment that differentially affected visual/perceptual compared to functional/associative knowledge. While acknowledging that the Sensory/Functional Theory cannot account for the existence of category-specific semantic deficits, Rosazza and colleagues (2003) contend that "...the presence of a more severe loss of specific visual rather than functional knowledge could support an interpretation according to the Sensory/Functional Theory" [sic] (p. 200). Our comments are divided into two parts. First, we point out that there is an asymmetry between evidence and theory: if there is clear evidence that "disconfirms" a given theory, evidence that is consistent with the theory cannot be argued to support the theory. Second, we argue that the performance profile of MA could potentially be relevant to other interpretations of category-specific deficits but that theoretical interpretations of the performance profile of patient MA are undermined by a lack of methodological rigor, as well as the generally weak data associated with the case.

Brain Injuries↗

Comments on 'Reconsidering the definition of a dose-volume histogram'--dose-mass histogram (DMH) versus dose-volume histogram (DVH) for predicting radiation-induced pneumonitis.

In a recently published paper (Nioutsikou et al 2005 Phys. Med. Biol. 50 L17) the authors showed that the use of the dose-mass histogram (DMH) concept is a more accurate descriptor of the dose delivered to lung than the traditionally used dose-volume histogram (DVH) concept. Furthermore, they state that if a functional imaging modality could also be registered to the anatomical imaging modality providing a functional weighting across the organ (functional mass) then the more general and realistic concept of the dose-functioning mass histogram (D[F]MH) could be an even more appropriate descriptor. The comments of the present letter to the editor are in line with the basic arguments of that work since their general conclusions appear to be supported by the comparison of the DMH and DVH concepts using radiobiological measures. In this study, it is examined whether the dose-mass histogram (DMH) concept deviated significantly from the widely used dose-volume histogram (DVH) concept regarding the expected lung complications and if there are clinical indications supporting these results. The problem was investigated theoretically by applying two hypothetical dose distributions (Gaussian and semi-Gaussian shaped) on two lungs of uniform and varying densities. The influence of the deviation between DVHs and DMHs on the treatment outcome was estimated by using the relative seriality and LKB models using the Gagliardi et al (2000 Int. J. Radiat. Oncol. Biol. Phys. 46 373) and Seppenwoolde et al (2003 Int. J. Radiat. Oncol. Biol. Phys. 55 724) parameter sets for radiation pneumonitis, respectively. Furthermore, the biological equivalent of their difference was estimated by the biologically effective uniform dose (D) and equivalent uniform dose (EUD) concepts, respectively. It is shown that the relation between the DVHs and DMHs varies depending on the underlying cell density distribution and the applied dose distribution. However, the range of their deviation in terms of the expected clinical outcome was proven to be very large. Concluding, the effectiveness of the dose distribution delivered to the patients seems to be more closely related to the radiation effects when using the DMH concept.

Dose-Response Relationship, Radiation↗

Comments on 'The effect of logarithmic compression on the estimation of the Nakagami parameter for ultrasonic tissue characterization'.

In a recently published paper (Tsui et al 2005 Phys. Med. Biol. 50 3235-44), the authors demonstrated estimation of the Nakagami parameter of the logcompressed envelopes and the application of such an approach in ultrasonic tissue characterization. The comments in this letter suggest that the authors ignored some important statistical properties of logcompressed data leading to serious errors in their studies and results.

Algorithms↗

Comments on 'The influence of cardiac preload and positive end-expiratory pressure on the pre-ejection period'.

The pre-ejection period (PEP) has been described as a potential parameter for monitoring cardiac preload in deeply sedated mechanically ventilated patients. Other authors have recently suggested that PEP is not sensitive to the changes in intravascular volume status in mechanically ventilated pigs which underwent acute hemorrhage. The present comment is an analysis of this recent animal investigation.

Animals↗

Public disclosure of health care performance reports: comments and reflections from Sweden.

In all countries quality improvement is a very important issue. At the same time the demands for information from consumers are increasing. By combining these two principles we can gain a great deal. In my opinion we will go both ways. Bad results, if publicly disclosed, are probably the strongest incentive to improve if they are reliable. Confidential performance feedback for self improvement is the way Sweden is heading at the moment. In the near future, I am sure, we will publish performance reports accompanied by analytic comments regarding quality indicators that are well defined and easy for consumers to evaluate. A pre-condition is that the medical profession must have time to get accustomed. Only experience will show how to devise the most effective means to improve quality and confidence in health care. We will follow the progress in the USA with great interest.

Consumer Advocacy↗

Help for the gatekeepers: comment and summation on the admission process.

The author comments on articles that discuss the roles of demographic variables, qualitative variables, and the interview in making sound selection for medical school admission; analyze the effectiveness of traditional predictors in selecting successful students; and examine the predictors that best identify minority students likely to succeed in medical training. Together, the articles review the literature, analyze the findings, and recommend sound practices and areas of future research germane to selecting students. The discussions highlight the predictor role, initial importance, and relatively short half-life of academic criteria in physicians' total careers, and emphasize that academic predictors must be complemented by other factors in the applicant's background. Because selection for medical school leads in almost all cases to eventual practice as a physician, the admission decision has far-reaching impact. Those concerned with the admission process should use the distilled information in these articles to improve the assessment of applicants and the selection process.

Achievement↗

It's management not payment that we should focus on: comments on Welch.

This comment discussed the ideas put forward by Peter Welch in his article on federal policy pertaining to managed care. Specifically, we assert that it is important to have as wide a data set as possible if one is to maximize the benefits of capitation. These benefits largely revolve around creating a tool that primarily represents a language that can facilitate communication between the financial and clinical sides of managed care.

Aged↗

Outpatient encounter data for risk adjustment--a view from Europe: comments on Welch.

This article comments from a European perspective on W. Pete Welch's article, which examines the use of outpatient encounter data for risk adjustment. Although diverse, Western European health care systems all seek to provide a comprehensive package of care, financed by premiums unrelated to health status. Some form of risk adjustment is therefore required as a basis for funding insurers in all systems. Two objectives have dominated: to secure equity between patients covered by different insurers and to ensure that (where implemented) competitive insurer markets operate efficiently. The commentary concludes that, although risk adjustment research of this type is important, the most fundamental requirement is to develop a more active purchasing function on the part of insurers.

Ambulatory Care↗

Comment on "Electromagnetic convective cells in a nonuniform dusty plasma".

Recently, Saleem and Haque [Phys. Rev. E 60, 7612 (1999)] concluded that in the presence of a perturbed electron current parallel to an external magnetic field, the dispersion relation of the electrostatic convective cell and the magnetostatic modes is not modified. In the present Comment, the properties of electromagnetic as well as electrostatic waves in a nonuniform dusty magnetoplasma are reexamined, to demonstrate that Eq. (13) of the paper by Saleem and Haque as well as their conclusions are erroneous.

Comment↗

Reply to "Comment on 'Long-range electrostatic interactions between like-charged colloids: steric and confinement effects' ".

In his Comment to [Phys. Rev. E 60, 6530 (1999)], Mateescu shows that while the effective interactions remain repulsive when the specific size of the microions is taken into account via a Modified Poisson-Boltzmann equation, a similar conclusion cannot be reached for the situation of complete lateral confinement. This point is correct but has already been considered in a more general study [Phys. Rev. E 62, R1465 (2000), where repulsion is generically obtained]; moreover, we argue that it illustrates the irrelevancy of the notion of pair potential in completely confined configurations, as shown in a simple example.

Comment↗

Comment on "Monte Carlo simulations for a Lotka-type model with reactant diffusion and interactions".

Discussing the effect of adsorbate-adsorbate lateral interactions on the kinetics of heterogeneous catalytic reactions, Zvejnieks and Kuzovkov [Phys. Rev. E 63, 051104 (2001)] conclude that in the case of adsorbed particles the Metropolis Monte Carlo dynamics is meaningless and propose to use their own dynamics, which is equivalent to the Glauber dynamics. In this Comment, I show that these and other conclusions and prescriptions by Zvejnieks and Kuzovkov are not in line with the general principles of simulations of rate processes in adsorbed overlayers.

Comment↗

Comment on "nonlinear viscosity and Grad's method".

In their recent paper [Phys. Rev. E 60, 4052 (1999)] Uribe and García-Colín suggest that the stress tensor associated with the nonlinear viscosity formula eta=eta(0)sinh (-1)kappa/kappa (kappa=a Rayleigh dissipation function) vanishes asymptotically as the magnitude of the velocity gradient increases. In this Comment, it is pointed out that their remark is invalid, because the stress tensor asymptotically exhibits a logarithmic kappa dependence. It is also pointed out that their evolution equations for the stress tensor components are missing the terms containing the velocity gradients in the transversal directions and, as a consequence, give rise to a vanishing shear stress, contrary to the experimental evidence of gas flow in a tube.

Comment↗

Comment on "monostable array-enhanced stochastic resonance".

Lindner et al. [Phys. Rev. E 63, 051107 (2001)] have reported multiple stochastic resonances (SRs) in an array of underdamped monostable nonlinear oscillators. This is in contrast to the single SR observed earlier in a similar but isolated oscillator. Though the idea that such an effect might occur is intuitively reasonable, the notation and the interpretation of some of the major results seem confusing. These issues are identified and some of them are clarified. In addition, comments are made on two possible extensions of the central idea of Lindner et al.: one of these promises to provide much more striking manifestations of multiple SR in arrays; the other significantly widens the range of systems in which multiple SRs may be observed.

Comment↗

Comment on "Atomic spectral line-free parameter deconvolution procedure".

Recently Milosavljević and Poparić [Phys. Rev. E 63, 036404 (2001)] proposed a method for the deconvolution of isolated asymmetric plasma broadened atomic (neutral) spectral lines. The authors claim that their method enables a complete plasma diagnostics by applying this deconvolution on a single experimental line profile. In the present Comment the proposed deconvolution procedure and its application are reexamined.

Comment↗

Comment on "Molecular gyroscopes and biological effects of weak extremely low-frequency magnetic fields".

A mechanism whereby reaction rates may be influenced by weak alternating magnetic fields has been suggested by Binhi and Savin [Phys. Rev. E 65, 051912 (2002)] to account for certain magnetobiological effects. It is proposed that the fields influence the probability of reaction of molecular rotators (gyroscopes) by inducing interference between eigenstates of angular momentum superposed in their wave functions. The predicted variation of reaction rate with the amplitude of the alternating field is found to be qualitatively consistent with observation. It is commented that the required interference occurs only in circumstances which are quite implausible, and that even if it were possible, the interference would not lead to a detectable magnetobiological effect.

Biophysical Phenomena↗

Comment on "Wealth condensation in Pareto macroeconomies".

In a recent study of the Pareto macroeconomy [Phys. Rev. E 65, 026102 (2002)], a surprising deviation to the power law distribution of the large wealths is reported. We comment that such a "corruption" phenomenon can be reproduced in a much simplified framework. The corruption disappears when the small wealths are further included in a mean-field treatment. The constraint of the total-wealth conservation leads to a cutoff in the power-law tail, in contrast to the prominent enhancement reported previously.

Comment↗

Comment on "Control of hyperchaos".

In this Comment we show that the adaptive adjustment mechanism proposed by Shouliang, Shaoqing, and Hengqiang [Phys. Rev. E 64, 056212 (2001)] does not ensure that the feedback system will converge to the desired orbit as the real system is, in general, not known.

Comment↗