PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “ENDOCARDITIS, INFECTIOUS”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 325 records · Page 18Linked to original sources
PubMed2000

[Infectious endocarditis].

The incidence of infective endocarditis has not decreased over the last years. Infective endocarditis remains severe: the mortality rate during the initial hospital stay is 15%, and a surgical intervention is needed in 25% of the cases. Stricter application of prophylaxis guidelines and better diagnostic and therapeutic management should decrease the frequency and severity of infective endocarditis.

Antibiotic Prophylaxis↗
PubMed2000

[Infectious endocarditis caused by a glycopeptide-resistant enterococus].

Enterococci are an important cause of infective endocarditis. Their resistance to most of the antibiotics involve real therapeutic problems. We report the first clinical isolate of glycopeptide resistant enterococcus from blood culture of patient with a prosthetic valve endocarditis. The strain is an E. faecium with a high level of resistance to vancomycin and teicoplanin (MIC > 256 mg/l), a low level of resistance to gentamycin (MIC = 6 mg/l) and susceptible to ampicillin (MIC = 1.5 mg/l). Therapeutic failure was observed leading to a surgical treatment. Therapy of such infection caused by multiresistant Enterococcus must be based on the study of bactericidal activity of antibiotic associations. In order to control the spread of this emerging resistance, the implementation of control measures is necessary.

Adult↗
PubMed2001

[Neurological manifestation of infectious endocarditis: 14 cases].

Fourteen cases of infective endocarditis revealed by neurological manifestations are reported: 8 strokes (one transient ischemic attack, one regressing and 6 completed strokes), 2 intracranial hematomas (one due to ruptured mycotic aneurysm), 2 toxic encephalopathies, one grand mal seizure, one suppurative meningitis. Most of them were native valve endocarditis, and streptococcus was the most frequently responsible bacteria. The outcome was characterized by a high mortality (6 cases) and morbidity (4 cases). This emphasizes the usefulness of preventing antibiotherapy in patients with known predisposing factors and the necessity for these patients to be admitted in neurological intensive care units.

Adult↗
PubMed2001

[Acute infectious endocarditis].

Acute infective endocarditis are due to highly virulent microorganisms, such as Staphylococcus aureus, able to invade normal endocardium, causing fulminant local damages (valvular destruction) as well as general damages (sepsis, metastasis), so that clinical manifestations are usually dramatic. Empirical antimicrobial therapy must be given immediately, using combinations active against the most commonly encountered pathogens. Other treatments are frequently necessary: medical therapy for heart failure, surgery of valvular reconstruction or replacement, respiratory assistance and other supportive measures. Such management requires cooperation of several disciplines.

Anti-Bacterial Agents↗
PubMed2001

[The course of infectious endocarditis in IV drug abusers and in subjects predisposed to heart diseases].

40 patients with infective endocarditis (IE) abusing intravenous drugs (heroin, opium surrogates) and 9 IE patients predisposed to heart diseases were examined by Duke diagnostic criteria. IE in drug abusers is characterized by acute course of the disease with affection of the intact valves of the right heart (97.5%) and septicemia provoked by high-virulent microflora (Staph. aureus in 65%). Drug abusers showed the following principal clinical syndromes of IE: thromboembolic (65%); septic with formation of acute DIC syndrome (75%), development of pyodestructive foci in the organs and polyorganic insufficiency (23.3%); acute circulatory insufficiency (37.5%); secondary nephropathy (100%). In IE abusers with predisposition to heart diseases IE ran subacutely in the presence of bacteriemia caused by low-virulent microflora (Strept. viridans in 11%) or in the absence of microbial growth in blood seeding (78%). High IE lethality in drug abusers (40%) is explained both by severe complications and concomitant diseases (viral hepatitis B and C, HIV infection, etc.).

Adolescent↗
PubMed1975

[Immunologic study of subacute infectious endocarditis through the search for circulating immune complexes. Preliminary results apropos of 13 cases].

The detection of circulating immune complexes by precipitation by polyethylene glycol represents a valuable technique of study in sub-acute bacterial endocarditis. In a series of 13 patients, this measurement was carried out, confirming the quasi-constant presence of circulating immune complexes in active S.B.E. This might be of diagnostic value in forms with negative blood culture and, further, make it possible, subsequently, to find the antigen responsible by dissociation of the circulating immune complexes.

Adult↗
PubMed2002

[Infectious endocarditis of the left heart atrium in injection drug addicts].

AIM: To study etiology, clinical picture, course and prognosis of left heart infection endocarditis (LHIE) in drug addicts. MATERIAL AND METHODS: 61 drug addicts entered the study. 14 of them had lesions of the left heart valves (group 1), 11--of the right and left heart valves (group 2), 36--of the tricuspid valve (group 3), 39 control patients with LHIE had no addiction. Mean age in group 1 was 25.9 +/- 8.8 years, in group 4--48.3 +/- 12.6 years, p < 0.001. RESULTS: Females prevailed in group 3, males--in group 4. Splenomegaly was more frequent in the addicts. Lung lesions (abscesses and infarction) prevailed in groups 2 and 3. Cardiac failure was found more frequently in groups 1 and 4, edema--in group 3, brain affections--in groups 1 and 4. Renal damage was encountered with equal frequency in the addicts and non-addicts. The addicts had, largely, infarctions, non-addicts--glomerulonephritis. Viral hepatitis C was associated with drug addiction. Blood seedings were on the whole positive in 54%, in drug addicts--in 69%. St. aureus predominated (44%). In group 3 it was detected in 72%. It was higher than in groups 4 and 1 (p < 0.001, p < 0.01, respectively). Lethality in group 1 (57%) was higher than in group 3 (22%, p < 0.05) and group 2 (18%, p < 0.01). The leading cause of death in group 1 was cerebral thromboembolism with development of meningoencephalitis. Other causes--progressive cardiac and renal failure.

Adult↗