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At least 325 records · Page 18Linked to original sources
PubMed1985

Chemotherapy of eyelid and peritorbital tumors.

Eight patients with nine histologically proven BCC or SCC involving the eyelids and periorbital tissues were treated with systemic and/or local (iontophoresis) chemotherapy using cisplatin and doxorubicin. All patients had either refused surgery, would have required extensive procedures, or had medical problems contraindicating surgery. Systemic chemotherapy induced a CR or PR in eight of nine lesions. No patient has required maintenance chemotherapy and no significant toxic side effects were encountered. The length of follow-up ranges from 2 to 50 months. Iontophoretic therapy with cisplatin was used to treat five small foci of new, recurrent or persistent tumor(s) in three of these patients, and resulted in a partial response in all five lesions. Systemic or local chemotherapy offers an alternative to current standard forms of treatment for BCC and SCC in selected cases.

Aged↗
PubMed1985

15 years' experience with treatment of basal cell carcinomas of the skin with curettage.

At the Department of Dermatology in the Finsen Institute we have since the beginning of the 1960's been especially interested in the treatment of skin tumors. Curettage is used in combination with a number of other treatment modalities and, therefore, it has been important to assess the value of curettage as the only therapy of basal cell carcinomas (b.c.c.). Gradually, curettage has come to be the normal treatment of b.c.c. of the skin in very large patient materials. The curettage is supplemented with X-ray therapy in cases where the demarcation in the depth is uncertain, while electrocauterization is used if the limits between a tumor and the surrounding skin are not sharp. 3 patient groups have been followed at regular intervals, and the results of these are described and discussed. The groups comprise firstly 525 patients with solitary tumors, secondly a special group consisting of 180 b.c.c. of the eyelid region and thirdly a group of 673 patients with multiple b.c.c. Considering the benign character of the tumors, their frequent localization on the face, the low age of many patients, and especially the nice results from the cosmetic point of view, it is concluded that curettage as the only treatment of b.c.c. ought to be a part of the therapeutic routine in a modern Department of Dermatology.

Adult↗
PubMed1985

[Surgical therapy of late x-ray-induced skin lesions].

The method as well as the degree of surgery in treatment of skin lesions induced by radiation must be individually planned, considering site and severity of the lesions. On account of insufficient blood supply and, consequently, high susceptibility to infection, only myocutaneous or full thickness grafts are suitable for the covering of the defects. Due to reduced elasticity, high tension at the receptor site often leads to rejection of the transplant. These problems are illustrated by some cases showing lesions on the face, breast, and abdominal wall; the difficulties of treatment are discussed.

Breast Neoplasms↗
PubMed1985

Intractable periocular hemangioma of infancy.

A case of intractable giant periocular hemangioma in an infant is described. This histologically benign but locally invasive tumour is reviewed from the point of view of complications and available treatment modalities. The indications for therapy with a relatively new antifibrinolytic agent, tranexamic acid, are cited.

Blepharoptosis↗