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At least 325 records · Page 18Linked to original sources

Hereditary hemorrhagic telangiectasia with oral manifestations. Report of periodontal treatment in two cases.

The periodontal conditions of two patients with hereditary hemorrhagic telangiectasia were successfully treated by a two-phase plan. The first phase of treatment eliminated inflammation from local etiologic factors by removing plaque and plaque-retaining factors. The second phase eliminated the residual anatomic defects of periodontal disease. Gingival bleeding has been indicated as a symptomatic factor of hereditary hemorrhagic telangiectasia, but such bleeding is more likely the result of periodontal inflammation.

Dental Scaling↗

Pregnancy tumor: an analysis.

There is some disagreement about the validity of the clinical term "pregnancy tumor." On the basis of its clinical presentation and histologic appearance, some authors believe that it simply represents a pyogenic granuloma (PG), whereas others believe that the lesion is unique because of the apparent influence of female sex hormones. In an attempt to resolve this problem, a study was undertaken to determine whether a significant correlation exists between PG and pregnancy, and whether the clinical term applies to the other epulides. The study involved 42 epulides diagnosed clinically as pregnancy tumors. A chi-square analysis comparing 32 of these lesions with 757 epulides occurring in women revealed a significant disproportion in the number of PGs, whereas the number of peripheral ossifying fibromas and peripheral giant cell granulomas were within the expected range. Very few focal fibrous hyperplasias (fibromas) were diagnosed as pregnancy tumors. Clinical and behavioral features of pregnancy tumors diagnosed microscopically as PGs were also analyzed. The results indicated that the diagnosis of pregnancy tumor is valid clinically in describing a PG occurring in pregnancy, because it describes a distinct lesion not on the basis of histologic features but on etiology, biologic behavior, and treatment protocol.

Adolescent↗

Oral melanotic macules. A review of 353 cases.

Clinical and histopathologic data were obtained on 353 cases of oral melanotic macules. The mean age at the time of diagnosis for all sites was 43.1 years. A significant predilection for females (p < 0.001) was noted and the most common location was the lower lip (33.0%). The mean size of the lesions was 6.8 mm. Brown was the most common color (64.9%), and most (66.0%) of the lesions were described as flat. Melanin was evident in both the basal cell layer and lamina propria in 93.5% of the cases.

Adult↗

Free and acetylated polyamines as markers of oral cavity tumors.

Differences in tissue concentrations of N1- and N8-acetylspermidine and cadaverine in squamous cell carcinoma of the oral cavity compared to the surrounding healthy tissue, as well as to epulides and other benign oral lesions (papillomas, lipomas, and fibromas) are assessed. The results indicate that only N1-acetylspermidine has use as a marker for diagnosis because its concentration is higher in malignant tissue. Its use in prognosis and posttreatment monitoring requires further exploration.

Acetyltransferases↗

A trial of ascorbic acid and of multivitamin supplementation on the oral health of West African children.

204 children between the ages of 1.5 and 6.5 years living in a West African village where the incidence of gingivitis and bleeding gums is about 40% of the population at the end of the rainy season, were given vitamin C or a placebo for 69 days, followed by a multivitamin supplement or placebo for 47 days. The condition of their gums was continuously monitored by trained field workers and by a paediatrician during the supplementation period, and was also assessed in greater detail by the paediatrician at the beginning and end of each treatment period. No benefit of either type of supplement could be detected, either on incidence of bleeding, or on over-all severity of gingivitis, although there was a clear-cut seasonal trend towards lower incidence of bleeding in both groups as the study progressed.

Ascorbic Acid↗

An unusual epithelial neoplasm of gingiva resembling the keratoacanthoma.

An unusual, tumour-like mass protruding from labial and palatal gingivae and surrounding the unerupted canine in a 12-year-old child is described. Clinically, the lesion was felt to be aggressive but histologically, the most likely diagnosis was keratoacanthoma, probably of the nodulovegetating type. Following excision of the mass, healing has been uneventful. Whether or not the histological diagnosis of keratoacanthoma is accepted, rather than an unusual odontogenic neoplasm, this case illustrates the existence of an entity comprising well-differentiated islands and cysts of squamous epithelium with a rapid growth pattern.

Carcinoma, Squamous Cell↗

Malignant melanoma of the oral cavity--an increasing clinical diagnosis?

Oral malignant melanoma is fortunately a rare lesion. However the actual incidence in the population at present is unknown but may be increasing. The overall prognosis remains poor despite more radical surgery with adjuvant radiotherapy, chemotherapy and immunotherapy. The clinical presentation of oral malignant melanoma can vary widely from a typically pigmented macular or proliferative lesion to a non-pigmented soft vascular tumour; single or multiple, primary or metastatic. Our experience of five patients with malignant melanoma of the oral cavity is presented and the management of such lesions discussed.

Aged↗

Oral focal mucinosis.

Two cases of oral focal mucinosis are described. Both were diagnosed clinically as fibroma of the gingiva. The clinical and histopathologic features of this unusual lesion are discussed.

Adult↗