Nifedipine-induced gingival hyperplasia.
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This case study reports on the management of a woman suffering from thrombocytopenic purpura who was referred to the periodontal clinic with gingival swelling and bleeding. This condition was related to nifedipine therapy for hypertension.
Cyclosporine is a strong immunosuppressive drug, which is used specially in transplantation patients, however in some cases, like others medicines it causes, gingival overgrowth. In the present article we present five transplantations patients, (one of liver, and four of kidney), whom have taken this drug since more than a year at different dosages. One of them, never has presented overgrowth, whereas the rest cases have needed this specific periodontal treatment to solve hyperplasy. After this work, we don't find clear relationship between drug dosage-age-effect over tissues.
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Since the use of cyclosporine A therapy in kidney, cardiac hepatitis livers pancrease transplants, the oral surgeon have seen gingival overgrowth under this immunosuppressive drug. In this article the authors reports 2 cases and accomplishes light and electron microscopic study. Gingivectomy is exposed.
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