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At least 325 records · Page 18Linked to original sources
PubMed2006

[Rational treatment of diabetes mellitus in Siauliai and Telsiai regions, Lithuania].

OBJECTIVE: The evaluation of adherence to guidelines on rationality in prescribing reimbursed medicines for the treatment of diabetes mellitus. MATERIAL AND METHODS: A retrospective evaluation of drug utilization in national public health insurance database and analysis of 906 case histories of diabetic patients in respect of nonadherence to guidelines. RESULTS: A total of 184 (20.3%) case histories with 370 events were found to be nonadherent to: a) national guidelines on prescription of medicines (66.49%); b) authorized indications and contraindications (13.24%); c) insufficient monitoring (4.32%); d) nonadherence to the recommendations for prescription writing (11.35%); and e) nonadherence to the requirements for service provisions (4.6%). The analysis of nonadherence to national guidelines revealed: 1) failure to assess patient's height, weight, and body mass index (30.1%); 2) poor glycemia control (26%); 3) failure in referring to an endocrinologist in case of noncontrolled glycemia (17.5%); 4) monotherapy with long-acting insulin or started combined oral therapy without monotherapy (10.2%); 5) noncompliance with the recommendations of endocrinologist (8.5%); 6) unsubstantiated changes in diabetes mellitus treatment (4.1%). Thiazolidinediones are often administered in case of liver failure or without investigation of its function (60.4%) or in case of heart failure (29.2%). CONCLUSIONS: 1) Nonadherence was observed in 20.3% of cases; 2) the most frequent cause was nonadherence to guidelines (66.5%) and to authorized indications and contraindications (13.2%); 3) thiazolidinediones were prescribed in the presence of the contraindications. The areas for intervention are: 1) more active monitoring of glycemia; 2) the assessment of height, weight, and body mass index; and 3) the prescription of thiazolidinediones according to authorized indications and contraindications.

Administration, Oral↗
PubMed1991

[Plasma apolipoproteins B and AI in healthy individuals and patients with coronary atherosclerosis in a male population from Lithuania].

The paper discusses the results from a study into apolipoproteins B (apo-B) and AI (apo-AI) and apoB/apo-AI ratios in the blood of 188 healthy donors and 122 male patients with coronary atherosclerosis. Atherosclerotic lesions were coronary angiographically documented. The study was performed (in two age groups of patients: 1) those under 45 years and 2) those over 45 years. A relationship was examined between the levels of apolipoproteins and the lesion of one, two, three or more coronary arteries in the two age groups. The studies indicate that there are various mechanisms responsible for the pathogenesis of atherosclerosis in the age groups in question. It is concluded that the younger a patient is, the higher probability that elevated blood apo-B levels are essential in the pathogenesis of coronary atherosclerosis is. Determination of plasma apo-B and apo-AI levels and apo-B/apo-AI ratios enables a potential number of diseased coronary arteries to be predicted.

Adult↗
PubMedDate not supplied

[Hygienic evaluation of nitrate levels in drinking water and vegetable food products in various regions of Lithuania].

Significantly higher nitrate content was detected in drinking water and vegetables grown by the rural population in the regions where industrial enterprises producing chemical fertilizers are located, as compared to the control regions. It has been concluded that a special attention should be paid to the daily level of nitrates ingested by the population (especially by children) in the industrial regions of the Republic and to their health state.

Adult↗
PubMed1991

[Atherosclerosis of the coronary arteries and the blood group in the population of Lithuania].

Data are reported on the relation between atherosclerosis of the coronary arteries and blood group. Examined were 291 patients in whom involvement of the coronary arteries was verified by means of coronarography and aortocoronary shunting. It was established that the group B blood was distinctly more frequent and group O blood was distinctly less frequently observed in male patients under 45 years. In male patients over 45 years of age the blood group apparently influenced advancing of atherosclerotic lesions of the coronary arteries. The obtained data indicate that the A and B blood groups are one of the genetically based factors of risk in the link of atherosclerosis pathogenesis.

ABO Blood-Group System↗
PubMed1989

[A program for the prevention of diabetes mellitus in Lithuania].

The Programme on Diabetes Mellitus Control is a constituent part of Integrated Programme on Chronic Non-infectious Diseases Control. The epidemiological evidence has demonstrated the high prevalence of deranged carbohydrate metabolism in the republic. Registers of carbohydrate metabolism disorders were created for the children's population of the Republic and the adult population of Kaunas and two agricultural-industrial regions. A school for diabetic patients and the society 'Insula' were organised. The research-practical programme is implemented in stages.

Adult↗