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Effect of age on creatine, nitrogen and phosphorus concentrations in the skeletal muscles of cockerels.

Effect of age on creatine, nitrogen and phosphorus concentrations in the skeletal muscles of cockerels. Acta physiol. pol., 1985, 36 (3): 201-207. In the studied life period from the age of 1 to 7 weeks the concentration of nitrogen increased in the muscles and that of phosphorus decreased. The relation between creatine concentration and the share of creatine nitrogen in the total nitrogen pool in the muscles, on the one hand, and the age, on the other hand, was curvilinear; the highest values were observed in cockerels aged 3 weeks. No significant differences were demonstrated in the concentrations of these components between the superficial pectoralis muscle and the deep pectoralis muscle. In the muscles of legs the concentrations of creatine, nitrogen and phosphorus were lower than in pectoralis muscles.

Aging↗

The influence of selection for increased body weight and sex on pectoralis major muscle weight during the embryonic and posthatch periods.

Skeletal muscle development and growth results from a complex series of highly organized processes. To address how myogenesis was influenced by selection for increased BW and by sex, both sexes from a turkey line (F) selected only for increased 16-wk BW and its genetic control line (RBC2) were used. Pectoralis major muscle was isolated and weighed from 15 individuals of each sex of the F and RBC2 lines at 14, 16, 18, 20, and 24 d of embryonic development and at 1, 8, 12, and 16 wk of age posthatch. The F line had significantly heavier p. major muscle weights than the RBC2 line beginning at 16 d of embryonic development, and the magnitude of the line differences generally increased with age through 16 wk posthatch The p. major muscle was consistently heavier in males than in females, but the differences between sexes were significant only at 16, 18, and 24 d of embryonic development and at 8 wk posthatch. There was no significant interaction between line and sex for weight of the p. major muscle at any age. The results indicated that selection for increased 16-wk BW in the F line altered growth of the p. major muscle by 16 d of embryonic development and changes were similar for both sexes.

Animals↗

Pectoralis major muscle transposition: an adjunct to laryngeal preservation in severe chondroradionecrosis.

Radiation-induced chondronecrosis of the larynx in early glottic cancer is a rare but serious complication, sometimes requiring total laryngectomy. We describe two patients who developed the major complication of chondroradionecrosis of the larynx 11 and 18 years after completion of radiotherapy. Both cases underwent excision of the overlying skin and of all infected and devitalized thyroid cartilage, followed by pectoralis major muscle transposition and split thickness skin grafting. This procedure resulted in a preservation of all laryngeal functions and also an acceptable cosmetic outcome.

Adult↗

Chondrosarcoma of the manubrium. Resection and reconstruction with pectoralis major muscle.

Chondrosarcomas of the sternum are best treated by resection with tumor-free margins. Reconstruction of the manubrium and superior aspect of the sternum is one of the most difficult challenges for the reconstructive surgeon. In the past, most of the structural stability following resection of this area has depended on the formation of dense fibrous tissue and scar. We presented a case of reconstruction of the bony defect with autogenous bone grafting in conjunction with transposition of the pectoralis major muscle for increased protection and stability of the chest wall as well as for nourishment for the bone graft.

Chondrosarcoma↗

[Recurrent periprosthetic capsular retraction under the pectoralis major muscle. Treatment, 2 unusual clinical cases].

Capsular contracture around breast prostheses still represents a challenge, in spite of the numerous papers published on this topic. The etiology and pathogenesis of this condition are perplexing resulting in considerable controversy concerning the rationale for surgical treatment. The authors report two cases of recurrent disease: one patient with recurrent contracture after breast augmentation, the other patient with recurrence after breast reconstruction. Both patients were operated according to an original technique which consists in a square-shaped incision of the pectoralis major muscle via an inframammary approach. This surgical technique allows the prosthesis to sink into deeper layers leading to a better shape of the breast and providing satisfactory skin cover of the prosthesis.

Breast↗

Pectoralis major muscle flap: a new support approach to mammaplasty, personal technique.

Despite the significant evolution of mammaplasty techniques, some undesirable changes on the operated breasts result in evident dissatisfaction for both patients and doctors. The main reason is that the breast has a tendency to resume its previous shape months after the operation. In pursuit of a procedure that would avoid this untoward morphologic evolution, we set to work on the development of a new approach of broad fixation to maintain the breast shape and to avoid ptosis by using the inferior third of the pectoralis major muscle. The authors report their experience with 46 consecutive cases of breast reduction and mastopexy operated between March 1994 and November 1995, studying the surgical procedure employed, its advantages, limitations, and possible complications.

Adolescent↗

[The application of transposition of pectoralis major muscle or myocutaneous flap in the repair of long-standing wound over the mandibulo-cervico-thoracic area].

The pectoralis major muscle or myocutaneous flap is characterized by its easy dissection and free rotation, as well as abundance of blood supply and tissue mass of the flap, so that it was often used in repairing the wound over the mandibulo-cervico-thoracic area. From 1989 to 1996, 11 cases with long-standing wound of this area were difficult to repair with the traditional method, but were treated with transposition of this type of myocutaneous flap. The myocutaneous flap was applied in 8 case and muscle flap in 3 case. The flap area ranged from 12 cm x 8 cm to 26 cm x 18 cm. All the flaps survived, and excellent results were achieved. The technique and design of the operation were reported in details. It was concluded that the process was easy to perform, and the flap had abundant blood supply and high resistance to infection.

Adolescent↗

[Successful surgical management for chronic sternal osteomyelitis and anterior mediastinal abscess after double valve replacement by total sternectomy and pectoralis major muscle flaps].

A 63-year-old woman underwent double (aortic and mitral) valve replacement in February, 1987. Thirty days later, purulent drainage developed at the sternotomy incision with high fever. Wound cultures revealed staphylococcus aureus. She was treated by local wound care with antibiotics. About one month later, she had a satisfactory wound healing. But three cutaneous fistulas with discharge emerged at the sternotomy incision in November (9 months later) and the cultures grew the same species. The fistulogram showed the communication between these tracts and the mediastinum. The diagnosis of chronic sternal osteomyelitis and anterior mediastinal abscess was made. At first the resection of the xiphoid process and the mediastinal drainage were carried out in March, 1988. Inspite of this procedure, she still had persistent purulent discharge. Then, en bloc excision of the infected sternum and the adjacent costal cartilage were performed in April. The defect was obliterated with the bilateral pectoralis major muscle flaps. After the radical operation, her wound was completely healed, even though the ventilatory support was needed for 24 days because of flail chest due to the anterior chest wall instability. Now she has been free from recurrence for four years. Total sternectomy and pectoralis major muscle plombage seem to be a very effective management in chronic sternal osteomyelitis.

Abscess↗