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At least 325 records · Page 18Linked to original sources
PubMed2001

A clinical study of a silicate toothpaste with extract from propolis.

Propolis is bee-produced substance with pronounced anti-inflammatory effect. It is an ingredient of many drugs; it is added to toothpastes as a prophylactic component for periodontal diseases. The plaque-cleaning, plaque-inhibiting and anti-inflammatory actions of the silicate paste were studied. The study included 42 individuals in good clinical health and a minimum of 20 intact teeth - 11, 16, 24, 31, 36, 46. Control exams were performed on days 1, 7, 14, 21 and 28. The baseline values gradually decreased after each control tooth brushing with a statistically significant difference between them. The toothpaste shows very good plaque-cleaning, plaque-inhibiting and anti-inflammatory effect.

Adolescent↗
PubMed2004

A novel oral hygiene system through integration of a sonic toothbrush and liquid toothpaste.

A novel system for home oral hygiene, the IntelliClean System from Sonicare and Crest is an integrated sonic toothbrush and liquid-toothpaste dispensing system. New research has established the ability of this system to reduce plaque, especially in interproximal regions, and to reduce gingivitis. The unique capability for the user to reapply liquid toothpaste during brushing (ie, re-dose) allows for a greater reduction in bacteria in the sulcus and an enhanced in-use experience that leads to improved compliance with brushing instruction, specifically longer brushing times. Through in vitro and in vivo studies, the system and its constituents have been shown to be safe for daily use.

Dental Devices, Home Care↗
PubMed2004

Brushing compliance with a novel integrated power toothbrush and toothpaste oral hygiene system.

Patient motivation can be an important factor in successful compliance with an oral hygiene program. However, it also can present the most difficulty with such compliance. For example, some conditions, such as gingivitis, may seem nonthreatening, making adherence to recommended regimens especially difficult to attain. A new power toothbrush technology with an integrated toothpaste system has been developed that increases a patient's ability and willingness to adopt recommended regimens. This article reviews this novel technology and reports on a study comparing it to a nonintegrated power toothbrush and regular toothpaste. The features of the novel toothbrush technology also are explained in the context of patient concordance vs patient compliance.

Adolescent↗
PubMed2006

[The preventive effectiveness in reducing tooth decay and decalcification of different concentration of fluoride toothpaste for orthodontic patients].

OBJECTIVE: To investigate the preventive effectiveness in reducing tooth decay and decalcification of different concentration of fluoride toothpaste for orthodontic patients. METHODS: 86 patients were divided into the first test group and the second test group. The patients of the first test group brushed tooth with 1.1% sodium fluoride and acidulated phosphate gel. The patients of the second test group brushed tooth with 0.243% sodium fluoride in a silica base. The extent of facial tooth decay and decalcification of the twelve upper and lower teeth from right cuspid to left cuspid was scored blindly and independently by four observers after 12 months of product use. The scores were rated either one (having tooth cavity/decalcification) or zero (no tooth cavity/decalcification). Four observer's readings were averaged per tooth, and then per patient for the two treatment groups. RESULTS: After 12 months of product use, the mean caries score of the first test group was 0.326, and the mean caries score of the second test group was 0.490. There was significant difference between them. CONCLUSION: A gel system containing 1.1% sodium fluoride and acidulated phosphate provides a clinically better efficacy in reducing tooth decay and decalcification than does a toothpaste containing 0.243% sodium fluoride in a silica base under and adjacent to orthodontic brackets used in orthodontic therapy.

Dental Caries↗
PubMed2006

[Clinical and laboratory evidence for effectiveness of whitening toothpastes].

The article presents clinical and laboratory data concerning application of whitening toothpastes "Rembrandt". The effects of these pastes on the soft tissues status, the content of mineral substances in enamel biopsy liquid, enamel surface were evaluated. The results confirm the necessity of differential application of agents for tooth whitening and also of using whitening toothpastes for improvement of teeth color.

Data Interpretation, Statistical↗
PubMedDate not supplied

[Study of the effectiveness of amine fluoride and stannous fluoride containing toothpaste and mouthwash].

AmF and SnF2 containing toothpastes (equally 750 ppm F-) and mouthrinses (equally 125 ppm F-) from the GABA International Agency were tested. After a five month treatment period (daily two times tooth cleaning), in the saliva of the examined persons the germ counts of the S. mutans and Lactobacillus showed a decreasing tendency, though the change was not statistically significant. The control group used NaF containing cleaners (toothpaste; 1500 ppm F-, mouthrinse; 250 ppm F-) for also a five month treatment period. Within this group the germ counts of the microorganisms of the examined saliva did not change markedly.

Amines↗
PubMed1989

[Clinical test of two toothpastes of different composition].

In two series of clinical tests, the effect of two toothpastes of differing formulation were examined in respect of their plaque removal efficiency and their influence on inflammatory reactions of the periodontal margin. The remarkable improvements in the oral health of a group of "non-dentists" compared to "dentists" are certainly attributable to personal motivation and instruction on oral hygiene with brush and toothpaste, but also to the formulation of the paste which may have influenced these results.

Clinical Trials as Topic↗
PubMed1979

Polishing effect and abrasion of five toothpastes on dental enamel.

Prepared enamel samples were polished with one of 5 different toothpastes, dulled by acid treatment and repolished with the same toothpaste. The lustre change was measured by reflectometry and the micromorphological aspects of abrasion on enamel were investigated with the scanning electron microscope.

Acid Etching, Dental↗
PubMed1988

[Removability of tooth deposits by cleaning with toothbrushes and toothpaste].

The abrasion strength of the exogenous pellicle (EP) was investigated in in vitro experiments on extracted human teeth. The aim of the study was to elucidate the effect of daily brushing on the EP. EP-coated tooth specimens were cleansed under in vivo-like conditions. Five toothpastes with different degrees of abrasiveness were variously diluted with artificial saliva. The evaluation was done on the transmission electron microscope. The individual toothpastes differed significantly with respect to their abrasive effect on EP, which extended from only a slight effect on EP, which extended from only a slight effect to extensive removal of the pellicle. EP abrasion was considerably reduced by increasing dilution of the pastes with artificial saliva. No changes of the EP could be observed after brushing with only the toothbrush and saliva.

Dental Pellicle↗
PubMedDate not supplied

Safety evaluation of toothpaste containing chloroform. II. Long term studies in rats.

The results of a preliminary rangefinding 13-wk oral toxicity study and of two longer term studies on chloroform in toothpaste base are reported. Significant changes in serum enzymes and certain haemotological parameters were seen at the higher dose-levels in the rangefinding study. Intercurrent disease made it necessary to terminate the first long-term experiment prematurely after 1 yr. No evidence of serious toxicity was recorded. In the second long-term experiment, groups of 50 caesarian-derived SPF Sprague-Dawley rats of each sex received either the equivalent of 60 mg CHCl3/kg/d in toothpaste base or the vehicle only, by gavage on 6 d/wk for 80 wk and were then observed for up to a further 15 wk. Chloroform-treated rats of both sexes survived better than the controls, though both groups had a high incidence of non-neoplastic respiratory and renal disease. Female rats gave a consistent finding of decrease in plasma cholinesterase, shown to be related to activity against butyrylcholine but not acetyl-beta-methylcholine. Tumours of various sites were seen in 39 percent of chloroform-treated rats of both sexes examined histologically, compared with 38 percent of vehicle controls. There were no treatment-related effects on the incidence of liver or kidney tumours. Histologically-malignant mammary tumours were reported in more treated than control rats, but the difference in incidence was not statistically significant.

Animals↗
PubMed1980

Perioral leukoderma simulating vitiligo from use of a toothpaste containing cinnamic aldehyde.

Perioral leukoderma simulating vitiligo developed in a 25-year-old woman. A patch test to cinnamic aldehyde was positive; depigmentation was observed at the patch test site three months after initial application. No changes in pigmentation occurred from a concomitant allergic patch test reaction to neomycin sulfate; only hyperpigmentation occurred at the site of an irritant patch test reaction to nonanoic acid. A toothpaste containing cinnamic aldehyde was implicated; perioral hypopigmentation resolved when a toothpaste without cinnamic aldehyde was substituted. A repeated patch test to cinnamic aldehyde again showed depigmentation at the patch test site three months after application.

Acrolein↗
PubMedDate not supplied

[Changes in the properties of the enamel of the permanent teeth in children using fluoride-containing toothpastes].

Focal demineralization of the enamel of permanent teeth was studied in 104 schoolchildren aged 9 to 12 over the course of prophylaxis (cleaning the teeth with fluorine-containing toothpastes). The parameters checked up were the intensity of coloring, size and electric conductivity of the spots, and the rate of remineralization of the enamel of permanent teeth. For a year a strong correlation between the tested characteristics of the enamel and saliva was observed. Some age-specific characteristics of permanent teeth enamel were detected. Age group of 11 to 12 years should be distinguished in prophylactic and control groups, because it is at this age that all the tested properties of the enamel are the most liable to change: electric conductivity, permeability, and remineralization rate. This period seems to be characterized by a specific reaction of all systems and organs of the body to environmental exposures. Remineralizing prophylaxis was found to be the most effective at the age of 9 to 10 years. The findings permit us emphasize the contribution of fluorine contained in the Blendax fluorine-containing toothpaste used by the children to the major components of the pathologic process (white spots) and enamel remineralization at the stage of its maturation.

Child↗
PubMed1995

Toothpaste Fluocaril bi-fluoré 250 in the therapy of cervical dentin hypersensitivity, plaque score influencing.

The presented study verifies the desensibilization effect and the plaque score influence of a therapeutical toothpaste Fluocaril bi-fluoré 250 applied in a chosen group of patients with sensitive exposed tooth necks. In the course of six-week application of the toothpaste Fluocaril bi-fluoré 250, a decrease of the sensitivity of the exposed dentin, tested by cold and tactile stimuli and an improvement of the oral hygiene estimated with the help of plaque score were observed in the studied group. After withdrawal of the treatment, the estimated criteria returned to the initial values recorded at the beginning of the experiment.

Adolescent↗
PubMed2006

Determination of exposure and probable ingestion of fluoride through tea, toothpaste, tobacco and pan masala.

Levels of water soluble and acid soluble fluoride in tea, toothpaste, tobacco and pan masala (mouth freshener) were estimated. These items are, generally, ignored while calculating the total dietary intake of fluoride. Tea, toothpaste, tobacco, pan masala (with tobacco and without tobacco) frequently expose human body to 3.88-137.09, 53.5-338.5, 28.0-113.0, 16.5-306.5 and 23.5-185.0 microg of fluoride per gram of these items, respectively. An effort was also made to quantify, on the basis of available studies, the probable human ingestion of fluoride through these substances. Increased leaching of fluoride from some of these substances has been observed in acidic conditions in the present study. The results can be extrapolated to acidic conditions of human stomach.

Dentifrices↗
PubMed1990

Desmond Greer Walker Award. Enamel mottling in a non-fluoride community since the advent of fluoride toothpastes.

In 1987 an assessment of mottling in incisor teeth was carried out on a random sample of 12-year-old children in Liverpool, England. The number of children examined was 471. All of these children were born and had lived in Liverpool when the fluoride content of the water supply had averaged 0.1 parts/10(6). During this time the market share of fluoride toothpastes had increased from 5% in the early 1970s to 91.8% in 1987. The mouth prevalence of mottling was found to be 31.1%. The tooth prevalence of mottling was found to be 7.83%. There was no sex difference. The data obtained was compared with findings in 1974-75 in Liverpool before the advent of fluoride toothpastes. The data suggests that there has been a decrease in the prevalence of mottling in Liverpool since 1974-75.

Chi-Square Distribution↗
PubMedDate not supplied

Profilometric and microradiographic studies on the effects of toothpaste and acidic gel abrasivity on sound and demineralized bovine dental enamel.

The objective of this study was to assess the abrasive effects of toothpastes and acidic F gels on sound and demineralized enamel. Pairs of enamel specimens were cut from bovine incisors, embedded in epoxy resin and polished. An artificial subsurface lesion of 80-90 microm depth was created in one specimen from each pair. The samples were covered with adhesive tape, thereby exposing the enamel for abrasivity testing. All samples were divided into six groups of 15 and brushed with a slurry (1:3) of F gel or toothpaste and human saliva. Brushing with water (control) or with slurry was carried out (16,000 strokes) using a medium toothbrush (load 275 g) mounted in a brushing machine. Abrasion was evaluated using laser profilometry, and was about 50% less on sound than on demineralized enamel (p < 0.001). In the latter, brushing with water (0.09 +/- 0.03 microm) or with fluoride-free gel (0.08 +/- 0.03 microm) resulted in negligible wear. With a medium-abrasive paste (1.76 +/- 0.85 microm) and an acidic F gel (2.48 +/- 0.72 microm), brushing abrasion was significantly greater (p < 0.001) than with a low-abrasive paste (0.84 +/- 0.38 microm). The greatest wear (16.6 +/- 10.8 microm) was observed with high-abrasive paste (p < 0.001), and here transversal microradiography revealed a complete loss of the pseudointact surface after brushing. In vitro formed caries-like lesions can be abraded (by toothbrushing) more easily than sound enamel; hence, initial white spot lesions should preferably be brushed with oral hygiene products of low abrasivity.

Amines↗