PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “BALSAM”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 343 records · Page 19Linked to original sources

Theoretical note: the C/T ratio in artificial neural networks.

This paper describes computer simulations of the effect of the C/T ratio on acquisition rate in artificial neural networks. The networks consisted of neural processing elements that functioned according to a neurocomputational model whose learning rule is consistent with information on dopaminergic mechanisms of reinforcement. In Simulation 1, three comparisons were made: constant C and variable T, variable C and constant T, and a constant C/T with variable C and T. In the last two comparisons, C was manipulated by changing the probability of reinforcement within the intertrial interval (ITI), in the absence of the conditioned stimulus (CS). Acquisition rate tended to increase with C/T, and the invariant ratio had no effect. In Simulation 2, C was manipulated by changing the ITI, with continuous reinforcement in the presence of the CS and no reinforcements in its absence. Results were comparable to those obtained in Simulation 1. Simulation 3 further explored the effect of the invariant ratio, but with larger absolute values of C and T, which slowed acquisition significantly. The results parallel some experimental findings and theoretical implications of the Gibbon-Balsam model, showing that they can emerge from the moment-to-moment dynamics of a neural-network model. In contrast to that model, however, Simulation 3 suggests that the effect of invariant C/T ratios may be bounded.

Computer Simulation↗

Identification of diterpenes in canvas painting varnishes by gas chromatography-mass spectrometry with combined derivatisation.

A derivatisation method that combines the formation of ethyl esters from the carboxylic groups and trimethylsilyl ethers from hydroxyl groups of the components of diterpenic resins is presented in this paper. This methodology involves two experimental steps: (1) formation of ethyl esters using ethyl chloroformate; and (2) the esterified compounds are lead to react with trimethylsilylimidazole to form the corresponding trimethylsilyl ethers. The main advantage of the proposed method is the possibility of performing simultaneously the analysis of amino acids from proteins, fatty acids from drying oils, and diterpenic compounds from natural resins usually found in works of art. This methodology is of considerable interest due to the requirements of minimum sampling that usually involves the analysis of works of art. A chemometric study has been developed to adjust the optimal working conditions of the proposed derivatisation method in which chromatographic peak areas of the larixyl acetate derivative and the abietic acid derivative referred to n-hexadecane as internal standard have been compared. Samples of Venetian turpentine naturally aged have been used in this study. Finally, the efficiency of the proposed derivatisation method has been tested on other diterpenic resins and pigments commonly used in fine arts such as Strasbourg turpentine, Canada balsam, colophony, copper resinate and a sample from a Renaissance Altarpiece.

Diterpenes↗

Aromatic resin characterisation by gas chromatography-mass spectrometry. Raw and archaeological materials.

An analytical procedure based on alkaline hydrolysis, solvent extraction and trimethyl-silylation followed by gas chromatography-mass spectrometry (GC-MS) analysis was used to study the chemical composition of benzoe and storax resins, water-insoluble exudates of trees of the Styrax and Liquidambar genus. They are chemically characterised by having aromatic acids, alcohols and esters as their main components and are thus known as aromatic and/or balsamic resins. This analytical procedure allowed us to characterise the main components of the two resins and, even though cinnamic acid is the main component of both the resins, the presence of other characteristic aromatic compounds and triterpenes permitted us to distinguish between the two materials. All the compounds identified in benzoe resin were detected in an archaeological organic residue from an Egyptian ceramic censer (fifth to seventh centuries a.d.), thus proving that this resin was used as one of the components of the mixture of organic materials burned as incense. These results provide the first chemical evidence of the presence of benzoe resin in an archaeological material from Mediterranean area.

Archaeology↗

Clonal variation in heavy metal accumulation and biomass production in a poplar coppice culture. II. Vertical distribution and phytoextraction potential.

Short rotation coppice cultures (SRC) are intensively managed, high-density plantations of multi-shoot trees. In April 1996, an SRC field trial with 17 different poplar clones was established in Boom (Belgium) on a former waste disposal site. In December 1996 and January 2001, all shoots were cut back to a height of 5 cm to create a coppice culture. For six clones, wood and bark were sampled at the bottom, middle and top of a shoot in August and November 2002. No significant height effect of metal concentration was found, but for wood, metal concentrations generally increased toward the top of the shoot in August, and decreased toward the top of the shoot in November. Phytoextraction potential of a clone was primarily determined by metal concentration and by biomass production. Shoot size and number of shoots per stool were less important, as a high biomass production could be achieved by producing a few large shoots or many smaller shoots. Clone Fritzi Pauley accumulated 1.4 kg ha(-1) of Al over two years; Wolterson and Balsam Spire showed a relatively high accumulation of Cd and Zn, i.e. averaging, respectively 47 and 57 g ha(-1) for Cd and 2.4 and 2.0 kg ha(-1) for Zn over two years.

Biomass↗

Patch test results from the Mayo Clinic Contact Dermatitis Group, 1998-2000.

BACKGROUND: Patch testing is a diagnostic tool for the evaluation of patients with suspected allergic contact dermatitis. A standard series of allergens similar to that used by the North American Contact Dermatitis Group (NACDG) is used at Mayo Clinic. OBJECTIVE: Our aim was to report the results of patch testing with a standard series at Mayo Clinic from July 1, 1998, to Dec 31, 2000 and to compare our findings with those of the NACDG during the same period. METHODS: The results of patch testing with the standard series at Mayo Clinic were examined. Positive reaction rates were compared between Mayo Clinic and the NACDG. RESULTS: During the 30-month period, 1324 Mayo Clinic patients were patch tested with a standard series of allergens (mean, 60 allergens), whereas the NACDG standard series during this period included 50 allergens. Overall, 917 patients (69.3%) had at least one positive reaction and 606 patients (45.8%) had two or more positive reactions. The 10 allergens used both by Mayo Clinic and by the NACDG that most frequently caused positive reactions were nickel sulfate hexahydrate, balsam of Peru (Myroxylon pereirae), neomycin sulfate, cobalt chloride, fragrance mix, potassium dichromate (0.25%), thimerosal, bacitracin, formaldehyde, and glutaraldehyde. Statistically significant differences in positive reaction rates (P < .05) were observed for 12 of the 43 allergens common to both Mayo Clinic and the NACDG. CONCLUSION: With large standard patch test series, one can identify commonly encountered and potentially relevant contact allergens.

Adolescent↗

"The herbs that have the property of healing...,": the phytotherapy in Don Quixote.

Don Quixote, the most outstanding novel of the Spanish literature, represents a documentary source widely used among those specialists who intend to deepen in the knowledge of the late Renaissance society. In this sense, Don Quixote has been also studied from a medical perspective, including a general therapeutical view (oils, ointments, balms, poultices, syrups and other pharmacy preparations). We have tackled Don Quixote from the phytotherapeutic and ethnopharmacological perspective, a barely explored field. In this work, we intend to study the medicinal plants used during the Cervantine time for the treatment de multiples diseases (sedatives like opium, laxatives and emetics like hellebore, tonics and irritants) and we analyze the specific herbal therapies (balms, purgatives and emetics, ointments and poultices), which Cervantes reveals to us in his novel. Among them, the rhubarb root (Rheum spp. or Rumex spp.) should be highlighted, as well as the seeds of gopher spurge (Euphorbia lathyris), chicory (Cichorium intybus) and rosemary (Rosmarinus officinalis), primary component of the famous Balsam of Fierabras. Also, we have examined the possible scientific influences, which might have inspired Cervantes in this field, mainly the work of Andrés Laguna (Dioscorides' Materia Medica).

Famous Persons↗

Some toxicological studies of Momordica charantia L. on albino rats in normal and alloxan diabetic rats.

Momordica charantia L. (MC) (Cucurbitaceae) commonly known as balsam pear, bitter gourd or karela, used in several purposes in traditional medicine is an important medicinal plant. Two sets of experiments were carried out, the first experiment indicated that the LD(50) for MC juice and alcoholic extracts were 91.9 and 362.34 mg/100g b.wt., respectively, of subcutaneously "s.c." injected mice. The toxic signs were recorded within the first 24 h post-injection. The second experiment was performed to evaluate the effect of MC juice and alcoholic extracts on blood glucose and other biochemical parameters in normal and diabetic rats. Both extracts induced a significant decrease in serum glucose levels in normal and diabetic rats. The two extracts did not show any significant effect in urea, creatinine, ALT, AST and AP in normal rat, while in diabetic rats the two extracts caused a significant decrease in serum urea, creatinine, ALT, AST, AP, cholesterol and triglyceride levels. Also, these results suggested that MC extracts possesses anti-diabetic, hepato-renal protective and hypolipidemic effect in alloxan-induced diabetic rats. Thus, MC is alternative therapy that has primarily been used for lowering blood glucose levels in patients with diabetes mellitus.

Administration, Oral↗

Separation of kaempferols in Impatients balsamina flowers by capillary electrophoresis with electrochemical detection.

Capillary electrophoresis with wall-jet amperometric detection was used to detect kaempferol and its derivatives kaempferol-3-glucoside, kaempferol-3-glucosylrhamnoside and kaempferol-3-(p-coumaroyl)glucoside. The influence of buffer pH on separation was investigated and optimized. With a phosphate buffer at pH 7.5, nearly complete separation of the four kaempferols was achieved according to their different electrophoretic mobilities. The detection potential was also evaluated and optimized. At detection potential of +0.80 V vs. saturated calomel electrode, an amperometric response with high sensitivity and stability was obtained for these four compounds. Detection limit estimated for all the kaempferols examined was less than 1.4 fmol, based on S/N=3. The use of this method for the separation and detection of these compounds present in balsam flowers (Impatiens balsamina) is reported.

Electrochemistry↗

Developmental expression and stress induction of glutathione S-transferase in the spruce budworm, Choristoneura fumiferana.

Developmental and stress-induced expression of Choristoneura fumiferana glutathione S-transferase (CfGST) mRNA and protein were examined using Northern blots and Western blots. High levels of CfGST mRNA and protein were detected in 1st instar larvae and diapausing 2nd instar larvae. Expression of CfGST gradually decreased during larval development from 3rd to 5th instar, after which the expression increased once again, reaching peak levels in 6th instar larvae. CfGST mRNA and protein were undetectable in the pupal stage. Exposure to low temperature did not induce an increase in CfGST expression. Feeding on balsam fir foliage resulted in an increase in the expression of CfGST as compared to larvae that fed on artificial diet. The bacterial insecticide, Bacillus thuringiensis delta-endotoxin (Bt), the non-steroidal ecdysone analog, tebufenozide, and the synthetic pyrethroid, permethrin, induced the expression of CfGST mRNA in 5th instar larvae, whereas the chitin synthesis inhibitor, diflubenzuron, did not have any such effect. These results suggest that CfGST plays an important role in detoxifying various allelochemicals and insecticides in the spruce budworm. The developmental expression pattern strongly suggests that in addition to detoxification, CfGST might be involved in other functions.

Journal Article↗

Mercury levels in lichens from different host trees around a chlor-alkali plant in New Brunswick, Canada.

Mercury concentrations were determined in the epiphytic lichen Hypogymnia physodes along five transects starting from a chlor-alkali plant located at Dalhousie, New Brunswick, a landfill site and a nearby electricity generating station. Lichen samples were collected from white birch (Betula papyrifera) and spruce (Picea sp.) or balsam fir (Abies balsamea). Average lichen background mercury values were 0.088+/-0.005 microg/g from white birch and 0.148+/-0.046 microg/g from spruce trees, with a detection limit of 0.05 microg/g. The chlor-alkali plant and a power plant were identified, respectively, as a major source and a minor source of elevated mercury levels in lichens. At 125 m north-west of the New Brunswick Power plant, 0.28 microg/g Hg were found in Hypogymnia physodes from spruce trees, while at 250 m west (downwind) of the chlor-alkali plant, 3.66 microg/g of mercury were determined. High values, 0.98 microg/g in lichens from spruce trees and 0.79 microg/g in lichen samples from white birch were also measured at 125 m south of the chlor-alkali plant and decreased exponentially with distance. The sphere of influence of the chlor-alkali plant with respect to mercury deposition was estimated to extend 2.4-3.4 km from the plant. The mercury concentrations in Hypogymnia physodes collected from white birch were significantly lower than the concentrations in the same lichen from spruce trees in areas with elevated levels of mercury, but not in areas with low mercury levels. The magnitude of this difference dropped with distance from the source.

Air Pollutants↗

[Knowledge and problems regarding the topical treatment of leg ulcers: survey among general practitioners in the Indre-et-Loire area].

INTRODUCTION: The quantity of topical treatments for leg ulcers has increased over the last 15 years. OBJECTIVE: To determine the prescriptions for topical treatments and the problems in the management of leg ulcers using a questionnaire sent to general practitioners. MATERIAL AND METHODS: A questionnaire in 3 parts was sent to 95 general practitioners in the area working in 36 different districts with an explanatory letter. The first part was composed of 29 closed questions regarding prescription of topical treatment for leg ulcers. The second part, also closed, included 3 pictures showing a budding, a necrotic and a fibrinous ulcer. The physicians had to choose which treatment they would have prescribed and the frequency of dressings changes. The third part was composed of two open questions regarding the problems encountered. The survey started on May 1st and was closed on June 30th 2002. No reminders were sent. RESULTS: We received 52 replies, 49 of which were exploitable. Forty-five percent (43/95) did not reply. Occlusive dressings were widely prescribed (mainly hydrocolloid 38/49 and hydrocellular 28/49). Vaseline impregnated gauze were less prescribed (14/49). Dressings with balsam of Peru were prescribed often by 10 and occasionally by 27 general practitioners. Alginate or charcoal dressings were not always used appropriately. Antiseptics were prescribed by 10 physicians. Mechanical debridement of fibrinous or necrotic wounds was rarely used even for necrotic ulcers. Topical anesthetics were prescribed in 21 out of 33 cases of mechanical debridement. Some physicians referred care (n=4), others complained about lack of compliance (n=15), cost (n=14), local intolerance (n=10) and the excessively wide variety of dressings (n=10). We drew-up a synopsis with guidelines for treatment, which was sent to all the general practitioners who had participated in the survey. CONCLUSION: Forty-three of the 95 physicians approached did not reply. This poor response rate, which is common in this type of survey, may include physicians who are not at ease in the management of ulcers and this may bias the results. The physicians who replied to the survey knew the subject well but complained of the costs and variety of dressings. They were all eager to receive further information and guidelines.

Administration, Topical↗

Peristomal allergic contact dermatitis due to Gantrez in Stomahesive paste.

We report a case of severe peristomal dermatitis that was refractory to conventional treatments. Patch testing revealed positive allergies to myroxylon perulase (balsam of Peru), propylene glycol, Stomahesive paste, and Gantrez. This is the second reported case of patch-test-positive peristomal allergy to Gantrez.

Adolescent↗

North American Contact Dermatitis Group patch test results for the detection of delayed-type hypersensitivity to topical allergens.

BACKGROUND: Allergic contact dermatitis is a significant cause of cutaneous disease affecting many individuals. Patch testing, when used properly, often provides support for the diagnosis of allergic contact dermatitis. OBJECTIVE: This article reports patch testing results from July 1, 1994, to June 30, 1996, by the North American Contact Dermatitis Group (NACDG). METHODS: Patients evaluated in our patch test clinics were tested with the same screening series of allergens by the use of a standardized patch testing technique. The data from these patients were recorded on a standard computer entry form and analyzed. RESULTS: Forty-nine allergens were tested on 3120 patients. Budesonide was added to the series in July 1995 and tested on 1678 patients. Of these patients, 66.5% had positive allergic patch test reactions, and 57% had at least one allergic reaction that was felt to be clinically relevant to the present or past dermatitis. The 20 screening allergens commercially available to United States dermatologists in the Allergen Patch Test Kit, accounted for only 54.1% of the patients with positive allergic reactions. The additional 30 allergens on the NACDG screening series accounted for 47% of patients with positive allergic reactions. Had the Allergen Patch Test Kit alone been used, 12.4% of all patients tested may have had their disease misclassified as a nonallergic disorder, and an additional 34.4% of all tested patients would not have had their allergies fully defined. Among those patients with positive responses to the supplemental allergens, 81% of the responses were of present or past relevance. The 12 most frequent contact allergens were nickel sulfate, fragrance mix, thimerosal, quaternium-15, neomycin sulfate, formaldehyde, bacitracin, thiuram mix, balsam of Peru, cobalt chloride, para-phenylenediamine, and carba mix. The present relevance varied with the specific allergen from 10.7% (thimerosal) to 85.7% (quaternium-15). Among newer allergens, methyldibromoglutaronitrile/phenoxyethanol (cosmetic preservative) caused positive allergic reactions in 2% of the patients; tixocortol-21-pivalate and budesonide (corticosteroids), in 2.0% and 1.1% of the patients, respectively; and ethylene urea/melamine formaldehyde mix (textile resin), in 5% of the patients. CONCLUSION: The usefulness of patch testing is enhanced with the number of allergens tested, because allergens not found on the commercially available screening series in the United States frequently give relevant allergic reactions.

Allergens↗

[Auguste Lumière, pioneer of the modern cicatrization].

At the "Grand Café" in Paris, on december 28, 1895 Louis and Auguste Lumiere displayed the cinematograph, a technical innovation that revolutionized the nascent motion picture. It was the first public projection of a film. While Louis continues his work on pictures and invents autochrome plates for colour photography, Auguste focused his interests on biology and medicine. Since Ambroise Paré, few doctors have been interested in the healing process. Although Carrel and Lecomte Du Nouy published the first studies in the early twentieth century, Auguste Lumière was a pioneer in the modern research and treatment of wounds. He applied the principles of experimental medicine. In his research he used 44 dogs to study the healing speed and the scar quality in certain areas and under general conditions. In the winter of 1914-1915 he studied in Lyon several hundred wounds of war casualties. In 1922 he established and published in a marvellous book the principles of normal healing. In the department of Pr Leon Bérard he was shocked by the fetidness of the wards where the dried bandages were changed once a week. In 1915 he perfected a revolutionary sterilized "treatment-bandage" consisting of 2 mm stitched gauze saturated with Vaseline and Perou's balsam: the "Tulle Gras. In order to disinfect wounds, he used an iodized solution, sprayed in little droplets. The lives of Auguste and Louis Lumière were full of projects and inventions. When Auguste died in 1954 he had registered more than one hundred patents.

Cicatrix↗

The postprandial effect of components of the Mediterranean diet on endothelial function.

OBJECTIVES: This study investigated the postprandial effect of components of the Mediterranean diet on endothelial function, which may be an atherogenic factor. BACKGROUND: The Mediterranean diet, containing olive oil, pasta, fruits, vegetables, fish, and wine, is associated with an unexpectedly low rate of cardiovascular events. The Lyon Diet Heart Study found that a Mediterranean diet, which substituted omega-3-fatty-acid-enriched canola oil for the traditionally consumed omega-9 fatty-acid-rich olive oil, reduced cardiovascular events. METHODS: We fed 10 healthy, normolipidemic subjects five meals containing 900 kcal and 50 g fat. Three meals contained different fat sources: olive oil, canola oil, and salmon. Two olive oil meals also contained antioxidant vitamins (C and E) or foods (balsamic vinegar and salad). We measured serum lipoproteins and glucose and brachial artery flow-mediated vasodilation (FMD), an index of endothelial function, before and 3 h after each meal. RESULTS: All five meals significantly raised serum triglycerides, but did not change other lipoproteins or glucose 3 h postprandially. The olive oil meal reduced FMD 31% (14.3 +/- 4.2% to 9.9 +/- 4.5%, p = 0.008). An inverse correlation was observed between postprandial changes in serum triglycerides and FMD (r = -0.47, p < 0.05). The remaining four meals did not significantly reduce FMD. CONCLUSIONS: In terms of their postprandial effect on endothelial function, the beneficial components of the Mediterranean and Lyon Diet Heart Study diets appear to be antioxidant-rich foods, including vegetables, fruits, and their derivatives such as vinegar, and omega-3-rich fish and canola oils.

Adult↗

P.A. Schleisner: a pioneer in epidemiology.

In 1847 Schleisner (b. 1818) was sent from Copenhagen to the Vestmanna Islands in Iceland to study the epidemic of tetanus neonatorum. The neonatal mortality in those islands at that time was 600-740 per 1000 children. He built a small hospital and introduced treatment with Peru balsam of the umbilicus. Schleisner probably assumed that the infection was caused by airborne infection, contact infection or poor hygiene. The neonatal mortality fell to about 50 per 1000. Schleisner published his results in 1849. Semmelweiss published his observations in 1850 and Snow successfully fought the cholera epidemic in London in 1854. Schleisner deserves recognition as a pioneer in the field of epidemiology.

Epidemiology↗

Contact reactions to fragrances.

BACKGROUND: The most common reaction to fragrances is contact dermatitis, a delayed hypersensitivity reaction; however, other reactions include immediate contact reactions (contact urticaria) and photo-allergic reactions. Fragrance mix (FM) and balsam of Peru (BP) are used to screen for fragrance allergy. OBJECTIVE: To study the different types of allergic skin reactions to fragrance compounds. METHODS: Delayed hypersensitivity reactions to FM and BP were studied in 4,975 patients with suspected contact dermatitis by routine patch testing interpreted at 48 and 96 hours. In 664 of the patients, patch tests were read at 30 minutes to evaluate for immediate (wheal-and-flare) contact reactions and again at 48 and 96 hours. Photopatch tests to FM were performed in 111 patients with suspected photo-allergic dermatitis. RESULTS: Delayed contact reactions to FM occurred in 6.6% of females and 5.4% of males and to BP in 3.9% of females and 4.1% of males. Analysis of data over time (12 study years) showed an increased trend for reactions to fragrances, particularly in males. Sensitivity to other contact allergens (polysensitivity) was found in 62% of patients and polysensitivity presented more often with generalized contact dermatitis. The most sensitizing components of the fragrance mix that were tested in 38 patients were cinnamic alcohol, oak moss, and cinnamic aldehyde. There were 112 immediate patch test reactions to FM and 113 to BP in 664 patients. Immediate contact reactions were followed by delayed contact reactions in 13.4% of patients for FM and 8.8% for BP, representing a significant increase in the frequency of delayed contact reactions. Patients with immediate contact reactions to fragrances did not have a higher incidence of atopy (25.9%). No cases of positive photopatch test reactions to FM were seen. CONCLUSION: Fragrances commonly cause both delayed and immediate patch test reactions and patients with immediate contact reactions have an increase in delayed contact reactions to the same allergen.

Aromatherapy↗

Improved selective, simple, and contrast staining of acidophilic neurons with vanadium acid fuchsin.

Acidophilia is one of the hallmarks of acute neuronal damage and death in brain ischemia, excitotoxic and traumatic lesions and epileptic seizures. We here describe a novel and simple method for visualizing acidophilic neurons on paraffin sections, using vanadium acid fuchsin (VAF) staining and toluidine blue or hematoxylin counterstaining. Paraffin sections of the brain fixed in ethanol-formalin-acetic acid mixture are stained in 0.1% acid fuchsin containing 0.125% of ammonium metavanadate and 1% of glacial acetic acid, differentiated if overstained in 0.01% of borax solution, and counterstained with 0.05-0.025% of toluidine blue in acetate buffer (pH 3.3) or Gill's II hematoxylin. The sections are dehydrated, cleared in xylene and mounted in Canada balsam or any synthetic mounting media for light microscopy. VAF combined with toluidine blue or hematoxylin results in highly selective and reproducible color contrast staining of acidophilic neurons as well as glial nuclei and hyperchromatic neurons. As a progressive method, acid fuchsin staining usually does not require differentiation. The red acidophilic neurons are clearly visible on the background of non-damaged cells, which significantly facilitates the identification, and localization of damaged neurons, even at low magnification under the light microscope.

Acids↗