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PubMed1985

Exercise capacity correlating to exercise hemodynamics in coronary artery disease.

Forty-seven patients with coronary artery disease characterized by angina pectoris and/or old myocardial infarction underwent two maximal exercise tests, the supine ergometer test and the upright treadmill test, to study the relationship between exercise capacity and exercise hemodynamics. Subjects were divided into 3 groups: Group I (n = 19) achieved 25 or 50 watts, Group II (n = 15) achieved 75 watts and Group III (n = 13) achieved 100 or 125 watts. During ergometer exercise, the mean pulmonary capillary pressure elevated by 25.3 +/- 8.3 mmHg in Group I, 20.8 +/- 8.8 mmHg in Group II and 12.0 +/- 8.4 mmHg in Group III; the Group III value was significantly smaller than the other groups. The stroke volume index decreased by 3.6 +/- 8.8 ml/m2 in Group I, and increased by 10.9 +/- 8.7 ml/m2 in Group II and 10.7 +/- 14.7 ml/m2 in Group III. Thus, the impaired exercise capacity correlated with the abnormal exercise hemodynamics and its severity. In addition, the exercise capacity in the treadmill test was comparable to that in the ergometer test. It was concluded that the impaired exercise capacity in the both supine and upright exercise tests was well related to the development of abnormal exercise hemodynamics in patients with coronary artery disease.

Adult↗

PubMed1989

The significance of abnormal systolic blood pressure response during supine ergometer exercise and postexercise in ischemic heart disease, studied by exercise radionuclide ventriculography.

The prognostic value of abnormal postexercise systolic blood pressure (BP) response has not been investigated. Therefore, the significance of abnormal BP response during exercise and postexercise was examined in 169 patients with ischemic heart disease subjected to supine ergometer exercise gated equilibrium radionuclide ventriculography, coronary arteriography, and follow up averaging 3.6 years. Abnormal BP response during exercise (exertional "hypotension") was defined as 1) a failure of BP to rise by at least 11 mmHg or 2) an initial rise in BP but subsequent fall by more than 10 mmHg during exercise. Abnormal BP response during postexercise (postexercise "hypertension") was defined as an increase of more than 10 mmHg above the peak exercise BP. Of 169 patients, 51 (30%) had an abnormal BP response. Four types of BP response were identified: exertional "hypotension" (group 1a, n = 11), postexercise "hypertension" (group 1b, n = 30), exertional "hypotension" with postexercise "hypertension" (group 1c, n = 10) and normal BP response (group 2, n = 118). Both average exercise duration and peak heart rate were significantly lower in groups 1a, 1b and 1c than in group 2. The severity of exercise ST-segment depression was greater in groups 1b and 1c than in group 2. However, there was no significant difference in the severity of exercise ST-segment depression between group 1a and group 2. A decline in ejection fraction occurred more frequently in groups 1b and 1c than in group 2. Patients in groups 1a, 1b and 1c had more extensive coronary artery disease (CAD) than did patients in group 2. Medically treated patients with an abnormal BP response (groups 1a, 1b and 1c) had a poorer prognosis than did those with a normal BP response (group 2). These findings suggest that an abnormal BP response during supine exercise is infrequent, but is usually associated with impaired exercise tolerance and severe CAD. An abnormal postexercise BP response is also infrequent, but is more closely associated with evidence of myocardial ischemia and global left ventricular dysfunction than exertional "hypotension". In conclusion, postexercise "hypertension" has the same value as exertional "hypotension" as a predictor of poor prognosis.

Angina Pectoris↗

PubMed2004

Cooperative effects of exercise and occlusive stimuli on muscular function in low-intensity resistance exercise with moderate vascular occlusion.

To obtain insight into the relative contributions of exercise and occlusive stimuli to these muscular adaptations, the present study investigated the short- and long-term effects of varied combinations of low-intensity exercise and vascular occlusion. The subjects were separated into 3 groups (n = 6 for each group): low-intensity with vascular occlusion (LIO), low-intensity without vascular occlusion (LI), and vascular occlusion without exercise (VO). LIO and LI groups performed bilateral knee extension exercises in seated positions with an isotonic extension machine. In the LIO group, both sides of the thigh were pressure-occluded at the proximal end by means of a tourniquet during the entire session of exercise (approximately 10 min), whereas only the occlusion with the same pressure and duration was given in the VO group. The mean occlusion pressure was 218 +/- 8.1 mmHg (mean +/- SE). The exercise session consisted of five sets of exercise at an intensity of 10-20% 1RM and was performed twice a week for 8 wk. After the period of exercise training, isometric and isokinetic strengths at all velocities examined increased significantly in the LIO group (p < 0.05), whereas no significant change in strength was seen in the LI and VO groups. The increase in muscular strength in LIO was associated with a significant increase in the cross-sectional area of knee extensor muscles by 10.3 +/- 1.6%. The plasma growth hormone concentration measured 15 min after the session of exercise showed a marked increase only in LIO. The results showed that the low-intensity exercise and occlusive stimuli have cooperative effects in the long-term adaptation of muscle and an acute response to growth hormone.

Adaptation, Physiological↗

PubMed2001

The theory of planned behavior as related to intention to exercise and exercise behavior.

In a previously reported study we sought to assess the usefulness of the theory of planned behavior in explaining the exercise behavior of 73 adults enrolled in an exercise program over a 5-mo. period. The correlation between scores on Intention to Exercise and Exercise Behavior was moderate and inverse, conflicting with a primary tenet of the Theory of Planned Behavior. In this analysis of the data we sought to explain that finding by partitioning participants into groups based on a median split of their scores on Intention to Exercise and Exercise Behavior. Using the four Intention by Behavior groups as independent variables and scale scores as dependent variables, post hoc tests for Fitness Attitude showed significant differences only when High Intention conflicted with Low Intention, irrespective of Exercise Behavior. Perceived Behavioral Control showed opposite tendencies, i.e., differences were significant when High Behavior conflicted with Low Behavior, irrespective of Intention to Exercise. We conclude that Perceived Behavioral Control defines one's ultimate Exercise Behavior over a 5-mo. period while scores on Fitness Attitude define Intentions to Exercise.

Adult↗

PubMed2004

Mood changes after maximal exercise testing in subjects with symptoms of exercise dependence.

Considering exercise has positive and negative reinforcing properties, the mood states of sedentary, nonexercise-dependent and exercise-dependent volunteers were compared after maximal exercise testing. Mood status was evaluated by the Beck Depression Inventory, Trait-State Anxiety Inventory, and Profile of Mood States (POMS). No differences were detected before the test or after it, indicating little possibility of positive reinforcement. However, a significant reduction in the POMS Tension-Anxiety scores was observed in both exerciser groups (greater in the exercise-dependent group) but not in the sedentary group. Only in the exercise-dependent group were significant reductions in Anger and Total Mood Disorders scores observed compared with their pre-exercise scores. These data suggest that exercising has stronger negative reinforcement properties for exercise-dependent volunteers and is a factor which could increase the odds of their becoming dependent on exercise.

Adolescent↗

PubMed2002

Competition between internal and external sources of information during exercise: influence on RPE and the impact of the exercise load.

BACKGROUND: The purpose of this study was to investigate the influence of the exercise setting on perceived exertion during sustained low and high intensity cycling exercise. METHODS: Thirteen untrained males completed 4 15-min cycling sessions at 50% VO(2peak) and at 80% VO(2peak) under each of the following conditions: control, sensory deprived, video, and music. Ratings of perceived exertion (RPE) from Borg's 6-20 scale and heart rate (HR) were recorded at 5 min intervals during all sessions. RESULTS: RPE increased with exercise duration at both intensities and, as expected, was substantially higher at the harder workload. Exercising to music resulted in significantly lower RPE when compared to all other conditions at both the low and high workloads, while RPE was higher in the sensory deprived condition when compared to the other 3 conditions. However, RPE was similar for the control and video conditions at both workloads. A significant ordinal interaction existed between conditions and exercise duration during the low but not the high workload. While HR was higher for the harder workload and increased during each workload as a function of exercise duration, it was not different among the 4 conditions at either workload. CONCLUSIONS: Varying the type of sensory information available to the exercising individual did influence perceptual responses to the exercise with the degree of influence dependent on the intensity and duration of the exercise. These results are consistent with information processing models that suggest a limited capacity to attend to the information available. The type of information available, the work intensity, and the work duration were important elements influencing perceptual responses to exercise.

Adult↗

PubMed2002

Body temperature in sedentary adults during moderate exercise: no effect from exercise the day before.

BACKGROUND: Epidemiological findings show a continued presence of exertional heat injury during military basic recruit training. Current guidelines do not consider the carry-over effects of prior exercise or exposure to high ambient temperatures on the risk of succumbing to heat illness. HYPOTHESIS: From the epidemiological evidence we hypothesized that both prior exercise and exposure to hot environments on the day before would increase the core temperature response during exercise the next day. METHODS: Seven sedentary and non heat-acclimated men and women each performed eight randomized exposures involving treadmill walking for a maximum of 2 h every 2 wk. Two separate control trials at a wet bulb globe temperature (WBGT) of 22.5 degrees C and 26.5 degrees C consisted of exercise during the morning only. Six experimental trials involved successive days of exercise with trials on the second day at either a WBGT of 22.5 degrees C or 26.5 degrees C. All of the experimental trials involved walking during the first morning at a WBGT of 22.5 degrees C. Further, four of these trials included additional exercise in the afternoon at either a WBGT of 22.5 degrees C (two trials) or 29.5 degrees C (two trials). RESULTS: There was no impact of prior exercise on the day preceding the tests at either WBGT for any of the dependent measures. Rectal temperatures increased to 38.0 degrees C at the WBGT of 22.5 degrees C and to 38.5 degrees C for trials at 26.5 degrees C. There were also no carry-over effects from exercise conducted during the preceding afternoon. CONCLUSIONS: Under situations where individuals are well hydrated, rested, and free of injury, illness, and drug use, repeated exercise bouts on successive days do not alter the thermoregulatory response to exercise.

Adult↗

PubMed1992

Exercise thallium-201 tomographic scintigraphy in the diagnosis of coronary artery disease: emphasis on the effect of exercise level.

Exercise thallium-201 imaging using single-photon emission computed tomography (SPECT) was evaluated in 154 patients with angiographically documented coronary artery disease (CAD) and in 25 normal subjects. Of the 154 patients with CAD, 134 (87%) had abnormal thallium images. By contrast, only 77 (50%) patients had ischemic ST-segment depression (p < 0.001). Among 25 normal subjects, 20 had normal exercise SPECT images. The specificity of exercise SPECT imaging (80% or 20/25) in excluding patients with CAD was not significantly higher than that of exercise electrocardiography (76% or 19/25). For the detection of individual vessel involvement by analysis of territories of perfusion abnormalities, the sensitivity and specificity of exercise SPECT were 72% and 96% for the left anterior descending, 78% and 85% for the right coronary, and 47% and 98% for the left circumflex artery. Ninety (group 1) of the 154 patients with CAD achieved adequate exercise end points (ischemic ST-segment depression or > 85% of maximal predicted heart rate) and 64 (group 2) did not. Exercise SPECT showed significantly more perfusion abnormalities in group 1 than in group 2 (96% vs 75%, p < 0.001). We conclude that: (1) exercise SPECT thallium imaging is more sensitive than exercise electrocardiography for detecting patients with CAD; (2) the sensitivity of the test is affected by the level of exercise; and (3) it is valuable in the identification of individual vessel involvement.

Coronary Disease↗

PubMed1992

Accuracy of RPE from graded exercise to establish exercise training intensity.

The purpose of this investigation was to examine the accuracy of an exercise intensity prescription based upon perceptual responses obtained during a graded exercise test. Fifteen physically active men completed a graded exercise test (GXT) on a motor driven treadmill. Heart rate (HR), oxygen uptake (VO2), and RPE were measured each minute. An RPE intensity prescription was calculated as 75% of heart rate reserve from the GXT heart rate and RPE data. A minimum of 48 h later the subjects completed 10 min of exercise (EXT) on a level treadmill at the prescribed RPE. The subjects set the treadmill speed to elicit an exercise intensity equal to the prescribed perception of effort. There were significant mean differences (P < 0.05) in heart rate between the GXT (161.8 +/- 1.3) and EXT (154.9 +/- 4.5). However, by minute 6 the subjects were within four beats.min-1 of the target heart rate. There were no significant differences (P > 0.05) between GXT and EXT for VO2 (36.1 +/- 5.2, 33.1 +/- 6.4) and VE (64.1 +/- 10.8, 58.4 +/- 13.5) respectively. The present investigation demonstrates that a subject's perceptual response to a GXT can be used to accurately prescribe exercise intensity during level treadmill running. The intensity selected was within a typical range used for exercise prescription. The advantage of RPE as a method of exercise prescription is that an individual does not need to stop during exercise and measure a heart rate, but can make pace adjustments while exercising based solely upon the perception of effort.

Adult↗

PubMed2003

Effect of sodium citrate ingestion on oxygen debt & exercise endurance during supramaximal exercise.

BACKGROUND & OBJECTIVES: Administration of alkalinizing agents has been shown to improve performance in high intensity exercise. The present investigation was undertaken to determine whether sodium citrate ingestion enhances supramaximal endurance performance on a cycle ergometer and to assess its effect on oxygen debt incurred for the same supramaximal energy output. METHODS: Ten untrained, healthy, males performed acute intense bicycle ergometry exercise in two sessions viz., without (control) and with sodium citrate ingestion (experimental) in a dose of 0.5 g/kg body weight. Pre-exercise O2 consumption, pulse rate (PR) and respiratory rate (RR)/minute were recorded before both sessions. Exhaustion time (ET) was noted and work done calculated in the control session. Post-exercise PR and RR/min were also recorded in both sessions of study. Venous blood samples were drawn post-exercise and analysed for pH and lactate. O2 debt incurred was calculated in both sessions. RESULTS: Work output in supramaximal exercise averaged 69.40 +/- 15.31 Watts in the control session. None of the subjects in the experimental session complained of fatigue even when the exhaustion time noted in the control session was reached. Post-exercise tachycardia and tachypnoea were both significantly less (P<0.05 and P<0.001 respectively) in subjects after the experimental session as compared to the control. O2 debt incurred and lowering of blood pH were also significantly less (P<0.001) in the post-citrate phase. However, serum lactate increased significantly (P<0.05) in subjects after the experimental session. INTERPRETATION & CONCLUSION: Ingestion of sodium citrate prior to supramaximal exercise resulted in a reduction in post exercise O2 debt incurred. Blood pH was almost normal despite a higher serum lactate concentration. This probably led to an enhancement in exercise performance.

Adolescent↗

PubMed2005

Personality does not influence exercise-induced mood enhancement among female exercisers.

AIM: The present study investigated the influence of personality on exercise-induced mood changes. It was hypothesised that a) exercise would be associated with significant mood enhancement across all personality types, b) extroversion would be associated with positive mood and neuroticism with negative mood both pre- and post-exercise, and c) personality measures would interact with exercise-induced mood changes. METHODS: Participants were 90 female exercisers (M=25.8 y, SD=9.0 y) who completed the Eysenck Personality Inventory once and the Brunel Mood Scale before and after a 60-min exercise session. Median splits were used to group participants into 4 personality types: stable introverts (n=25), stable extroverts (n=20), neurotic introverts (n=26), and neurotic extroverts (n=19). RESULTS: Repeated measures MANOVA showed significant mood enhancement following exercise across all personality types. Neuroticism was associated with negative mood scores pre- and post-exercise but the effect of extroversion on reported mood was relatively weak. There was no significant interaction effect between exercise-induced mood enhancement and personality. CONCLUSIONS: Findings lend support to the notion that exercise is associated with improved mood. However, findings show that personality did not influence this effect, although neuroticism was associated with negative mood.

Adolescent↗

PubMed2005

[Evaluation of dynamic hyperinflation parameters and exercise capacity at maximal exercise in patients with COPD].

Hyperinflation is an important limiting factor for exercise performance in patients with chronic obstructive pulmonary disease (COPD). Hyperinflation can be determined by measuring residual volume (RV), functional residual capacity (FRC), and total lung capacity (TLC) at rest, and by measuring inspiratory capacity (IC) and end-expiratory lung volume (EELV) at maximal exercise. This study aimed to evaluate changes in hyperinflation parameters on maximal exercise in subjects with COPD. Patients with clinically stable COPD (n= 43) and healthy controls (n= 14) were included. Subjects performed pulmonary function tests and an incremental exercise test on cycle ergometry. Statistically significant differences (p< 0.05) were found regarding exercise test parameters including exercise duration, maximum oxygen uptake, breathing reserve, maximum minute ventilation, and breathing pattern between groups. There was significant increase in EELV (p< 0.05) and decrease in IC (p< 0.05) at maximum exercise when hyperinflation parameters were compared at baseline and maximum exercise. Our results showed that hyperinflation was evident at maximal exercise, although there were no hyperinflation findings at rest in subjects with COPD. We believe that in patients with COPD, it is better to evaluate hyperinflation at maximal exercise than at rest.

Exercise↗

PubMed1991

[Exercise-induced ST segment shift in vasospastic angina with special reference to comparisons between treadmill and bicycle ergometer exercise testings].

To assess the difference between cardiovascular responses to treadmill exercise (TM) and those to bicycle ergometer exercise (EM) in provoking coronary spasm, we compared the ST segment shifts (elevation or depression) during TM and EM in 67 patients with vasospastic angina. Coronary artery spasm was demonstrated on angiography. Both TM and EM were performed on the same day during a medication-free period. For both tests, multistage, symptom-limited exercise protocols were used; EM in the morning and TM in the afternoon. The results obtained were as follows: 1. Rate-pressure products at peak exercise during TM and EM were similar. Systolic blood pressure levels at peak exercise were higher during EM than during TM (p < 0.01). The patients' heart rates at peak exercise were higher during TM than during EM (p < 0.01). Diastolic blood pressure levels at peak exercise were higher during EM than during TM (p < 0.05). 2. Exercise-induced ST elevation occurred more frequently with TM than with EM (19% vs 9%, p < 0.05). 3. Exercise-induced ST depression was provided in 27 patients during TM and in 13 during EM (40% vs 19%, p < 0.01). Among 45 patients without significant lesions, ST depression occurred in 19 during TM, but in only 7 during EM (42% vs 16%, p < 0.01). In conclusion, coronary spasm seemed to occur more frequently with TM than with EM. The mechanism causing such difference remains to be elucidated, however, we speculate that the difference between TM and EM as to enhanced autonomous nervous system activity and coronary perfusion exercise may be related to the difference in the incidence of coronary spasm.

Aged↗

PubMed1990

Detecting asymptomatic coronary artery disease using routine exercise testing and exercise thallium scintigraphy in patients with atherosclerotic vascular disease.

ECG-monitored exercise testing has been proposed as a relatively inexpensive and effective means of screening for asymptomatic coronary artery disease in patients presenting for peripheral vascular surgery. Despite the fact that exercise thallium scintigraphy is also dependent on the patient's ability to exercise, using this test in conjunction with ECG-monitored exercise testing may enhance sensitivity and specificity of non-invasive evaluation. Thirty-two patients were subjected to ECG-monitored exercise testing, exercise thallium scintigraphy and coronary angiography. The sensitivity of ECG-monitored exercise testing for detecting coronary artery disease was calculated at 81.8% and the specificity at 87.5%, while the figures for exercise thallium scintigraphy were 73.1% and 33.3% respectively. Using these two methods in combination yielded a predictive accuracy of 90.6%. The only advantage of exercise thallium scintigraphy over exercise ECG appears to be in patients in whom the latter test could not be interpreted or was non-diagnostic.

Adult↗

PubMed1981

Exercise-induced asthma - a comparison between two modes of exercise stress.

Two types of treadmill exercise were performed by 10 asthmatics (mean age 32.4 +/- 8.9 years). One type of exercise was a steady state, submaximal effort lasting approximately 7 min. The other was a short, supramaximal effort designed to exhaust the subjects within 50 s. Ventilatory studies as well as gas exchange, arterial blood lactate (LA) and pH were measured pre- and post-exercise. The submaximal exercise caused the expected increase in Raw (19%) and a decrease in FEV1 (21%) and MMEF (20%) measured 10 min following exercise. In contrast, only the MMEF was reduced (26%) at 10 min after the short-exhaustive exercise. It was concluded that short (less than 1 min) and highly intense exercise challenge may cause a drastic fall in MMEF with no changes in FEV1.0 or Raw. It is postulated that the unequal ventilatory response to the two exercise modes is responsible for a greater respiratory heat loss during the long-submaximal exercise and consequently for the greater obstruction of the large airways. In addition the short-exhaustive exercise performed in this study may serve as a simple and accurate tool for detecting small airway obstruction as measured by the MMEF.

Adult↗

PubMed1996

Influence of the exercise protocol on hemodynamic, gas exchange, and neurohumoral responses to exercise in heart transplant recipients.

BACKGROUND: A gradual accommodation to increasing exercise loads has been recommended for exercise testing in denervated posttransplantation heart recipients. However, how the exercise protocol influence the hemodynamic, gas exchange, and hormonal response to exercise in this not been studied. METHODS: Nine heart transplant recipients tests incremental maximal bicycle ergometry tests in random order. Exercise stages of 1 and 3 minute durations were compared with matched work rate increments ranging between 30 and 40 W. Expiratory gas was measured continuously and arterial blood was sampled at each of the matched work rates. RESULTS: Total exercise duration was 6.4 +/- and 15.3 +/- 0.7 minutes for the 1-minute and 3-minute protocols, respectively. Maximal workload was significantly higher during the 1-minute versus the 3-minute protocol (238 +/- 9 versus 200 +/- 11 W, p < 0.001), but maximal oxygen uptake was not significantly different (25.5 +/- 1.1 versus 26.5 +/- 1.2 ml. min-1.kg-1). Hemodynamic, metabolic, and some hormonal parameters showed marked differences between the two protocols, with significantly higher responses observed during the 3-minute protocol for heart rate, ventilation, lactate, atrial natriuretic factor, and growth hormone. Catecholamine (epinephrine and norepinephrine) and insulin responses did not differ between the two tests. If expressed as a relative exercise intensity (percentage of maximal oxygen uptake) no differences in hormonal responses were observed between the two protocols, except for growth hormone response which remained higher during the 3-minute protocol. CONCLUSIONS: Although maximal oxygen uptake was independent of the exercise protocol in these heart transplant recipients, the exercise protocol has a major influence on the hormonal and metabolic response. The delayed response observed for oxygen uptake and hormonal responses suggests a significant physiologic lag time during the more rapidly incremental protocol. These differences should be taken into account when exercise is used as a method to evaluate the heart transplant recipient.

Adult↗

PubMed1996

Effects of mail-mediated, stage-matched exercise behavior change strategies on female adults' leisure-time exercise behavior.

This study compared three forms of mail-mediated exercise behavior change strategies on the weekly leisure time exercise behavior of individuals at different stages of exercise (SOE). Subjects were 113 healthy females, 22 to 50 years old (M = 36.9). After being classified by SOE, subjects were randomly assigned to receive one of three treatments: lifestyle exercise packet (LEP); structured exercise packet (SEP); or control packet. Packets were mailed to subjects at their worksite. After 31-days, 108 (95%) subjects responded to a query about their previous week's leisure-time exercise behavior. A 3 (SOE) x3 (Exercise group) x2 (Time) REANOVA revealed main effects for SOE (p < 0.0001), exercise group (p < 0.05), and time (p < 0.0001). No significant interactions were observed. Post-hoc testing showed that those in the action/maintenance stages differed from those in the preparation and precontemplation/contemplation stages (p < 0.01), and that LEP subjects reported significantly more weekly leisure-time exercise post-intervention compared to controls (p < 0.01). These findings suggest the LEP was the most effective strategy for encouraging weekly leisure-time exercise. Future research should be directed at corroborating these findings and determining the potential long-term value of this strategy in comparison to more traditional strategies.

Adult↗

PubMed1998

Effects of percutaneous balloon mitral valvuloplasty and exercise training on the kinetics of recovery oxygen consumption after exercise in patients with mitral stenosis.

AIMS: Kinetics of recovery oxygen consumption after exercise plays an important role in determining exercise capacity. This study was performed to assess the kinetics of recovery oxygen consumption in mitral stenosis and evaluate the effects of percutaneous balloon mitral valvuloplasty and exercise training on the kinetics. METHODS AND RESULTS: Thirty patients with mitral stenosis (valve area < or =1.0 cm2) and same sized age- and size-matched healthy volunteers were included for this study. All subjects performed maximal upright graded bicycle exercise. Thirty consecutive patients who underwent successful percutaneous balloon mitral valvuloplasty (valve area > or =1.5 cm2 and mitral regurgitation grade < or =2), were randomized to an exercise training group or non-training group. The exercise group performed daily exercise training for 3 months. Half-recovery time of peak oxygen consumption was significantly delayed in mitral stenosis as compared to normal subjects (120+/-42 s vs 59+/-5, P<0.01). Peak oxygen consumption (ml x min(-1) x kg(-1)) was significantly increased in both the training (16.8+/-4.9 to 25.3+/-6.9) and non-training groups (16.3+/-5.1 to 19.6+/-6.0) 3 months after percutaneous balloon mitral valvuloplasty. Half-recovery time of peak oxygen consumption was significantly shortened in the training group (124+/-39 to 76+/-13, P<0.01), but not in the non-training group (114+/-46 to 109+/-44 s, P=0.12) at 3 months follow-up. The degrees of symptomatic improvement after percutaneous balloon mitral valvuloplasty were more closely correlated with the changes of the half-recovery time of peak oxygen consumption than those of peak oxygen consumption. CONCLUSION: Kinetics of recovery oxygen consumption was markedly delayed in mitral stenosis, which was improved after exercise training but not after percutaneous balloon mitral valvuloplasty alone. These results suggest that adjunctive exercise training may be useful for improvement of recovery kinetics and subjective symptoms after percutaneous balloon mitral valvuloplasty.

Adult↗