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[Reduction of dental caries after two years with a combination of mouthwashes and topical fluorides].

The study's purpose was to evaluate the reduction of dental caries incidence by the association of two preventive methods. 246 students of both sexes aged from 7 to 11 years registered in "Escola de Educação Básica da Universidade Federal de Uberlândia" and living in the urbana area of Uberlândia, state of Minas Gerais, were examined. The sample was distributed into two groups: children from Group 1, which received a semestral topical application of Acidulated Fluor Phosphate at 1.23% and children from Group II, that besides the topical application above related (Group I) also received weekly mouthwashes of sodium fluoride aquesus solution at 0.2%. After two years of study DMFS index were tabled and statistically analysed. It was verified a reduction of 33.97% in the incidence of dental caries (in the permanent dentition). The difference between the Groups was significant at 5% level of confidence.

Brazil↗

Effect of fluoride topical solutions on enamel demineralization by lactate buffers and Streptococcus mutans in vitro.

Applications of APF and NaF solutions to extracted human teeth reduced the extent of enamel subsurface demineralization induced by colonization of S. mutans but were ineffective against demineralization by acid lactate buffers. It is concluded that the CaF2 formed on the tooth surface during the treatment is responsible for the protection observed.

Acidulated Phosphate Fluoride↗

Comparison of the effects of two topical fluoride regimens on demineralized enamel in vivo.

The purpose of this investigation was to study the intra-oral remineralization of acid-softened enamel by a NaF dentifrice compared with that from a combination of topical F agents. Bovine enamel slabs were demineralized with 0.1 mol/L lactic acid at pH 4.0 for 14 hr and then mounted in a removable mandibular appliance. Control slabs were worn for 96 hr by seven adult males who brushed daily with a F-free dentifrice. Test slabs were brushed with a NaF dentifrice 4 x/day or with the same dentifrice 4 x/day and a 0.02% APF mouthrinse and a 0.4% SnF2 gel which were applied once/day for three days. The natural dentition was also brushed with the NaF dentifrice during both test periods. Microhardness testing was performed on sound enamel, and after acid-softening, intra-oral exposure (IOE), and acid resistance testing (ART) in 0.01 mol/L lactic acid at pH 4.0 for 24 hr. Control and test slabs were etched with 0.5 mol/L HC1O4 for from 15 to 60 sec. The F content was measured with a F electrode and PO4 by spectrophotometry. Contact microradiography and image analyses were performed on control and test slabs so that changes in mineral content resulting from treatment could be assessed. Both test groups were significantly harder after both IOE and ART than were controls, but no differences appeared between the effects of the two test groups. The F content of control slabs was significantly less than that of both test groups, and the combination-treated slabs showed greater F than did the dentifrice-treated slabs.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Novel topical fluoride delivery system I: remineralization of ground bovine teeth.

Laboratory studies were carried out on a newly conceived fluoride-containing remineralizing system with bovine teeth. The prototype fluoride delivery device involved micronized calcium fluoride maintained at the tooth surface with a cellulose film. Together with salivary calcium and phosphate (or simulated saliva), this system was able to generate and maintain the appropriate thermodynamic activity driving force for significant fluorapatite deposition in a reasonably short time (approximately 48 hr).

Animals↗

Novel topical fluoride delivery system II: remineralization of human teeth.

A recently conceived calcium fluoride-containing remineralization system was tested using human teeth in vitro. The influence of several variables (surface pretreatment, demineralization time, and remineralization time) was studied. Appreciable levels of fluoride taken up by pumiced human teeth were found at depths up to 50 micrometers when remineralization was carried out in either the remineralizing solution or saliva. The successful performance of the delivery device in these laboratory studies is encouraging and indicates that the logical evolution of the crude devices studied thus far could lead to clinically practical fluoride delivery devices.

Fluorides↗

Comparison of three self-applied topical fluoride preparations for control of decalcification.

The purpose of this study was to compare the effectiveness of a 1100 ppm fluoride toothpaste used alone, or together with a 0.05% NaF rinse used once daily or a 0.4% SnF2 gel applied twice daily, in controlling the decalcification that often accompanies orthodontic treatment. Ninety-five consecutively treated adolescent patients were matched for age and sex and assigned to one of these three regimens. Single blind assessments of decalcification were performed on all labial surfaces of all erupted teeth before appliances were placed and 3 months after appliances were removed. Because the first molars had the highest decalcification scores, data for the whole mouth and for first molars were analyzed separately. When pre-treatment levels of decalcification were subtracted from post-treatment values, significantly lower decalcification scores (p < 0.05) were found for both whole mouth and first molars in the rinse and gel groups as compared with the control group (toothpaste alone). Although the gel group consistently had less decalcification than the rinse group, this difference only approached statistical significance. These results indicate that twice daily use of a 1100 ppm fluoride toothpaste and either a once-daily 0.05% NaF rinse or a twice-daily 0.4% SnF2 gel provides additional protection against decalcification beyond that achieved with toothpaste alone.

Adolescent↗