Colimycin in chronic purulent respiratory disorders.
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Patients enduring cancer of the upper respiratory tract present greater risk of developing a second neoplasm, either synchronous or metasynchronously. Possible causes of this major risk are studied, giving a special attention to the role released for the treatment done in the primary neoplasm, in the later appearance of the second one.
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Data in the Stockholm Regional Cancer Register were compared with death certificates for persons who died of carcinoma in 1978 and were domiciled in Stockholm County. Concordance between cancer register diagnosis and certified underlying cause of death was 87 per cent. Many malignant tumours in organs which often show metastases were unspecified by one of the registers. In many other cases of discordance, differing site codes denoted anatomically close-lying organs. Age distribution did not differ between concordant and discordant diagnostic groups. Coordination of the cancer register and the mortality statistics as regards coding routines and disease classification presumably would enhance inter-register comparability.
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1,600 deaths are attributed to cancer in the Canton of Vaud, representing 23% of the total mortality. The incidence rates by sex for 12 cancer sites are compared, the data being taken from 3 cancer registries : Vaud, Geneva and the Saar (West Germany). The most important risk factors are mentioned for those sites with the highest rates. For men, cancers of the upper digestive and respiratory tract rank second, when the expectation of life associated with the age of onset of tumours of this site is taken into account. The sex ratio of males to females is particularly high. Some hypotheses, based on epidemiological observations, are formulated as to the causes of cancer of the upper digestive and respiratory tract.
Morbidity structure among workers engaged into main production of nuclear industry had prevailing lung cancer (1.93 per 1,000), gastric carcinoma (1.09) and colon cancer (0.72). The lung cancer patients demonstrated the highest concentrations of uranium in lung tissue (0.8313 g/g) and liver tissue (0.3548 g/g); those with gastric carcinoma and of reference group--in lung radix nodes (0.1855 and 0.3685 g/g respectively).
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