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At least 343 records · Page 19Linked to original sources
PubMed1991

[The pathogenetic bases for chemotherapy in an experimental Salmonella infection].

The effect of etiotropic (polymyxin and adriblastin) and pathogenetic (levamisole and vitamin E) chemotherapy on lipid peroxidation (LPO), phagocyte functional activity and the process and outcomes of Salmonella infection was studied in rabbits. It was shown that development of salmonellosis was accompanied by activation of LPO which was phase-by-phase. There was synchronism in changing of LPO and neutrophilic phagocytic activity. Adriblastin and levamisole stimulated LPO and increased the neutrophilic phagocytic activity. Vitamin E inhibited LPO and had an unfavourable effect on the process and outcomes of the infection. The problem in differential use of the chemotherapeutic drugs with an account of their modulating effect on LPO is discussed.

Animals↗
PubMed2006

[Impending rupture of aneurysm of Salmonella-infected aortic arch].

We report a case of a 67-year-old man with Salmonella infected aortic arch aneurysm. The patient presented with persistent high fever, chest pain, back pain and hoarseness. Laboratory studies showed the presence of severe inflammation. Both impending rupture and saccular aneurysm were suspected by preoperative computed tomography (CT), magnetic resonance imaging (MRI) and angiography and diagnosis was, therefore difficult to make. We conducted semi-emergency total aortic arch replacement, under deep hypothermic circulatory arrest and retrograde cerebral perfusion. Salmonella was identified in the aneurysmal wall and antibiotics were administered for 6 weeks until CRP was normalized, when they were replaced by oral antibiotics. Postoperative course was uneventful. The patient was discharged on the 60th postoperative day. He continues to take oral antibiotics.

Aged↗
PubMed1988

Reduction of salmonella infection of broilers by spray application of intestinal microflora: a longitudinal study.

The Nurmi concept for diminishing salmonella infection of poultry by application of gastrointestinal microflora from adult birds into newly hatched chicks was tested in a field study in which 8 million broilers were involved. Half of the 284 flocks was treated in the hatchery by spray application of an undefined microflora propagated in SPF chicks. A significant reduction in salmonella-contaminated flocks, as well as in the number of infected broilers in these flocks was demonstrated. No undesirable side effects were detected. It was concluded that hygienic improvements in transportation and slaughtering of broilers are needed in order to maintain the reduced salmonella contamination rate.

Animals↗
PubMed1995

Evaluation of DNA fingerprinting by PFGE as an epidemiologic tool for Salmonella infections.

To evaluate DNA fingerprinting as an epidemiologic tool, pulsed-field gel electrophoresis (PFGE) was performed on isolates of Salmonella, including S. typhimurium, S. thompson, and S. enteritidis. Chromosomal DNA was digested with the restriction endonucleases Bln I and Xba I. The patterns of S. thompson and S. typhimurium isolates from various sources were different from one another. There was no correlation between the phage type and the digestion pattern of S. enteritidis isolates. Some strains belonging to one phage type were distinguished by their PFGE pattern in this study. These results suggest that the Bln I and Xba I digestion patterns of chromosomal DNA are useful for epidemiological analysis of an outbreak of Salmonella infection or food poisoning.

DNA Fingerprinting↗