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The role of sexual dysfunctions in inducing the use of drug in young males.

INTRODUCTION: Adolescence is one of the periods in which the risk of the initial use of drugs is high. Among the risk factors of first drug use, sexual disorders have been considered one of the possible reasons leading young males to substance abuse and addiction. AIM: To provide data supporting the "La Pera hypothesis", according to which, a very large percentage of young males begin to use drugs due to sexual problems. METHODS: A total of 86 subjects, recruited from 5 drug rehabilitation centers were invited to fill in a questionnaire with their personal data, toxicological history, sexual experiences as well as quality of performances. RESULTS: Approximately 50% of the entire sample used psychotropic drugs to improve their sexual performance with 30 subjects (34.1%) stating that their sexual disorder had influenced their decision to start taking drugs. Of these 30 subjects, 18 (60%) stated their sexual problem had influenced them a little, while in 8 (26.7%), it had influenced them a lot and in 4 (13.3%) it had been a decisive factor. The prevalence of sexual dysfunction prior to first drug use was greater among subjects whose sexual problems influenced their initial use of drugs compared to the remainder of the sample, the difference being statistically significant. CONCLUSIONS: These data are in accordance with the "La Pera hypothesis" based on the cause/effect relationship between sexual dysfunctions and initial use of drugs. It is urgent to demonstrate that sexual disorders lead to first drug use since sex education and early treatment of sexual dysfunctions could provide an effective tool for the primary prevention of substance abuse in young males.

Adult↗

The effect of drugs on male sexual function and fertility.

Drugs may have negative effects on male libido, erection, ejaculation and orgasm, as well as on fertility, and research on these effects is increasing. Libido may be decreased by drugs that block dopamine or testosterone, or that cause dysphoria. Erection may be decreased by drugs that divert blood flow from the penis, or drugs that affect spinal reflexes. Ganglion blockers may also inhibit erection. Ejaculation may be diminished by drugs that affect spinal reflexes or be inhibited by ganglion blockage. Enervation of the vas deferens and epididymis may be blocked and cause a smaller emission. Retrograde ejaculation may occur due to blockage of the internal urethral sphincter. Orgasm is usually inhibited by the drugs that inhibit ejaculation. Fertility is impaired by drugs that affect sexual performance or spermatogenesis. Major groups of drugs that may affect male sexual function include drugs of abuse, CNS depressants, antihypertensives, anticholinergics, psychotherapeutics, hormones, and cancer therapeutics, in addition to miscellaneous other agents. Information about these drugs has been arranged in tables so that the provider has a convenient reference to use when explaining to men the effect of drugs on sexual response and fertility.

Drug-Related Side Effects and Adverse Reactions↗

[A pilot study of sexual problems in chronic schizophrenia: a report on 51 cases].

In order to explore the sexual problems of chronic schizophrenics, 51 cases were investigated. The result showed that 42 cases (82.3%) had various kinds of sexual problems. The problems were erectile impotence, frigidity, premature ejaculation, no ejaculation, vaginismus and pain on coitus. Only 4 cases had increased sexual desire. The authors found that the main sexual problems of chronic schizophrenics were inhibited sexual desire and excitement. The authors suggested that the sexual problems of chronic schizophrenics were related to their conditions in the body, rapport with their wives or husbands and the severity of affect, thought and volition disturbances.

Adult↗

Sexual dysfunction associated with infertility. A comparison of sexual function during the fertile and the non-fertile phase of the menstrual cycle.

In a study of 40 couples with primary infertility, the "need to perform' over the fertile phase of the menstrual cycle was assessed. In 50% of women there was a statistically increased incidence of sexual dysfunction during this phase; loss of libido was the commonest dysfunction. In 30% of men a decrease in sexual function was experienced during the fertile phase of their partner's cycle, and 75% of men reported premature ejaculation during intercourse in greater than 10% of occasions--this was unaltered by the diagnosis of infertility. The frequency of intercourse was increased over the fertile phase. No correlation was found between sexual dysfunction and the identified infertile sexual partner.

Adult↗

The frequency of sexual problems among family practice patients.

Two hundred-twelve patients attending a family practice center participated in a questionnaire study of their sexual identity and function. Using conservative definitions of problems, 75% were identified as having at least one specific sexual problem area. Most of these problems were functional in nature and involved desire, arousal, or orgasm. While the frequency of sexual problems was high in both sexes among all age groups, identity problems were primarily seen among the young, and desire problems among older adults. The prevalence rate of reporting sexual problems did not differ significantly by sex. However, females reported more specific sexual problems than males. Only 26% of the subjects summarized their overall sexual lives as problematic and the vast majority of patients thought their family physicians were able to help with such problems. This study reaffirms the high prevalence of sexual disorders in the population. Given adequate training, family physicians may be the ideal providers of assistance for these problems.

Adolescent↗

Towards a better delineation of ejaculatory disorders.

The inconsistent use of the term "retarded ejaculation" demonstrates the conceptual confusion in the literature on ejaculatory dysfunctions. Therefore, a classification system is proposed which comprises three major groups of ejaculatory disorders: unsatisfactory timing of ejaculation (premature and retarded ejaculation), absence of ejaculation (partial and complete ejaculatory inability), and ejaculation without pleasure (ejaculatory anhedonia and painful ejaculation). A more accurate descriptive delineation of ejaculatory disorders has considerable implications for treatment which in some dysfunctions, especially primary complete ejaculatory inability, still has limited possibilities.

Ejaculation↗

Sexual medicine.

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Aged↗