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At least 343 records · Page 19Linked to original sources
PubMed1988

Infantile myofibromatosis: the most common fibrous tumor of infancy.

We describe the clinical courses of four infants with infantile myofibromatosis (IM). This entity is a mesenchymal disorder of early infancy characterized by the formation of tumors in skin, muscle, viscera, bone, and subcutaneous tissues. Previously known as congenital generalized fibromatosis, IM was formerly thought to be a rare condition that was frequently fatal. The majority of the 170 affected patients we describe have been diagnosed since 1980. Furthermore, the mortality rate for these patients is less than 15%. Our review includes the clinical manifestations, as well as histopathologic features, and discusses the prognosis in affected infants. We found that infants with solitary lesions or multiple lesions without visceral involvement generally have a benign course. However, in patients with the multicentric form of the disorder and visceral involvement, 73% have died. Because the lesions may not be easily discernible and most spontaneously resolve, the condition is underdiagnosed and underreported. IM is the most common fibrous tumor of infancy and must be considered when evaluating children who present with either solitary or multiple tumors, particularly during the neonatal period.

Female↗
PubMed1986

Solitary late recurrence of renal cell carcinoma.

Solitary late recurrence is an unpredictable behavior pattern of renal cell carcinoma. We describe a patient with recurrence at the cranial bone 10 years after surgical management and another with recurrence at the sacral bone 13 years after treatment with radiotherapy and alpha-interferon. Both patients have been followed satisfactorily for 9 months. Unpredictable behavior of renal cell carcinoma makes lifelong followup of patients necessary. If a solitary recurrence is detected operative management definitely should be considered depending on the site of recurrence.

Carcinoma, Renal Cell↗
PubMed1975

Intraspinal epidermoid tumor of the sacral canal presenting with urinary retention.

A case of epidermoid tumor of the sacral area with S3 root irritation resulting in bladder dysfunction is presented and its possible relationship to spinal puncture is discussed. Precautions should be taken to prevent this complication by using a stylet instead of a plain needle. The recognition of this complication should always be in the differential diagnosis of a child with back pain, gait abnormality and bladder dysfunction with a history of spinal puncture.

Back Pain↗
PubMed2004

[Intradural and cervical primary malignant melanoma. Case report and review of the literature].

Primary malignant melanoma of the central nervous system is an uncommon localization, first reported by Hirsberg in 1906. Since then, to our knowledge, only 39 cases have been reported in the literature. We present a case of primary intradural extra-medullary melanoma which developed in a 51-Year-old man who complained of pain in the lower cervical spine, difficulties in micturition and sexual impotence. The diagnosis was suspected at the MRI which showed a lesion with a paramagnetic signal and was confirmed by the histological examination. The resection was complete and the course has been satisfactory after 19 months follow-up.

Cervical Vertebrae↗
PubMed1997

Imaging of the spine. Techniques of MR imaging.

Recently, magnetic resonance (MR) imaging has become the preferred method of evaluation for spinal disorders. The vertebrae, intervertebral disks, ligaments, spinal canal, and neural foramen may all be evaluated using current MR imaging techniques. MR imaging with paramagnetic contrast has developed into a valuable technique for diagnosing a tumor, an infection, or a degenerative disease. Computed tomography remains the procedure of choice for examining fine cortical bone detail including evaluation of spine fractures and assessing neural foraminal size, but it is not sensitive for detecting marrow-infiltrating disorders.

Cervical Vertebrae↗
PubMed1998

Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results.

Percutaneous vertebroplasty with acrylic cement consists of injecting polymethylmethacrylate into vertebral bodies destabilized by osseous lesions. The aim is to obtain an analgesic effect by reinforcing lesions of the spine. The major indications are vertebral angiomas, osteoporotic vertebral crush syndromes, and malignant spinal tumors. The clinically significant complications occur predominantly in patients with spinal metastatics, but in the great majority of cases they resolve with medical treatment.

Anesthesia, General↗
PubMed1976

Metastasis of cancer to cancer: report of a case.

A case of primary, widely disseminated prostatic carcinoma causing bilateral urinary tract obstruction, hydronephrosis, and papillary necrosis and metastasizing in the substance of an unusual histologic variant of renal cell carcinoma and tubular adenoma of the same kidney is presented. Unusual incidental findings include isolated cardiac amyloidosis and myocardial abscesses. A brief review of the literature is presented. The peculiar tendency for renal cell carcinoma to be the host tumor for other primary carcinomas and various theories to account for this phenomenon are commented upon briefly.

Adenocarcinoma↗
PubMed1983

Neuroblastoma and the differential diagnosis of small-, round-, blue-cell tumors.

Of the solid tumors of childhood, neuroblastoma--the prototypic small-, round-, blue-cell neoplasm--occurs in the youngest patients and has shown the least predictable biologic behavior and response to therapy. It is often confused clinically and histologically with Wilms' tumor, rhabdomyosarcoma, lymphoma, and especially, Ewing's sarcoma. Certain clinical and histologic features that may be useful in prognosis have been identified, however, and a variety of distinctive light microscopic, electron microscopic, and immunohistochemical features may be useful in differentiating this and related tumors. Many of the varied techniques useful in the differential diagnosis of these tumors can now be employed routinely in most laboratories.

Cartilage Oligomeric Matrix Protein↗
PubMed1981

Meningioangiomatosis in the absence of von Recklinghausen's disease.

Two patients who had been having seizures for 10 years or longer were found to have a peculiar neoplastic alteration in the cerebral cortex. The lesion in both instances consisted of a combined proliferation of meningothelial and endothelial cells; and are best described as meningioangiomatosis. The tissues were surgically excised and the frequency and severity of the patients' seizures decreased. In neither instance were there stigmata of von Recklinghausen's disease. In one example, as long as 8 years after craniotomy, no evidence of any disorder of the peripheral nerve was found. A review showed that such lesions have always been associated with multiple intracranial and spinal neoplasms; therefore, these two patients appear to be unique.

Adolescent↗
PubMed1996

Pontine glioma with osteoblastic skeletal metastases in a child.

BACKGROUND: The development of systemic metastases from primary intracranial gliomas is rare. We report here a rare case of pontine glioma with osteoblastic skeletal metastases. CASE: This 12-year-old boy presented with a 4-month history of hoarseness, dysphagia, and a progressively ataxic gait. Cranial computed tomography (CT) and magnetic resonance imaging (MRI) revealed a brain stem tumor that was diagnosed as a low grade glioma by stereotactic biopsy. Twelve months later following chemotherapy and radiotherapy, neurologic examination and neuroradiologic studies disclosed a recurrence of the pontine glioma. Skeletal roentgenograms revealed widespread osteoblastic metastases in the skull, vertebral bodies, pelvis, and long bones. A specimen from the iliac bone demonstrated cells that were immunoreactive glial fibrillary acidic protein (GFAP). DISCUSSION: The mechanism of how glioma cells determine their biologic behavior at bony metastatic sites is not known. Infratentorial gliomas, which occur frequently in young patients and demonstrate active bony metabolism, may stimulate osteoblastic cells, and induce osteoblastic changes.

Bone Neoplasms↗