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The storage of teeth before reimplantation in monkeys. A histologic study.

This study is a histologic comparison of twenty teeth which were extracted, endodontically treated, stored for 7 days at +4 degrees C. and at -10 degrees C., and subsequently reimplanted in ten monkeys. In these monkeys, as controls, ten more teeth were extracted, endodontically treated, and immediately reimplanted. Up to 1 year, 100 per cent success was obtained in those teeth stored at +4 degrees C. before reimplantation, and only 50 per cent success was obtained in those teeth stored at -10 degrees C. before reimplantation.

Animals↗

Treatment of avulsed teeth with Emdogain--a case report.

The present case report describes the reimplantation of avulsed teeth with the treatment of Emdogain. Case was avulsed right maxillary permanent central and lateral incisor in a 9-year-old girl suffering from a traumatic injury. After pretreatment of avulsed teeth, Emdogain was applied to the root surface and into the extraction socket with subsequent replantation of the tooth. Evaluation parameters included horizontal and vertical percussion sound and periapical radiographs. At 1-2-6-12-month follow-up period, the clinical and radiographic appearance of the teeth showed resolution of mobility and no signs of replacement resorbption.

Child↗

[Pharma clinics. How I treat...dental emergencies in general practice].

Counselling and drug prescription are the only means for the phycisian to manage dental emergencies. Among these, some are infection related: pulpitis, apical and periodontal abscesses, acute necrotizing ulcerative gingivitis and alveolitis. Urgent medical treatment includes antibiotics, mouth rinses and analgesics except for pulpitis (pain caused by thermal stimuli) for which analgesics alone are prescribed. Infection non related dental emergencies are: hemorrhage for which the best treatment is compression; trauma, mainly dental avulsion for which reimplantation must be done as soon as possible; acute TMD such as open lock which can be reduced by the Nelaton handling.

Emergency Treatment↗

An electrophysiological study of the reinnervation of reimplanted and autotransplanted teeth in the cat.

There is evidence to suggest that some reimplanted and autotransplanted teeth are reinnervated, but the time-course of reinnervation and the properties and source of the reinnervating axons are not known. This reinnervation has been investigated using electrophysiological techniques in 6 adult cats. In each cat, one lower canine and three incisor teeth were extracted and immediately reimplanted. Three other lower incisor teeth were transplanted into an edentulous area. The teeth were splinted in position for 6 weeks. Bipolar electrical stimulation of 22 of the 38 successfully reimplanted or autotransplanted teeth evoked a jaw-opening reflex within 9-24 weeks of the surgery. The reflex had a raised threshold and increased latency. Twenty-four weeks after reimplantation or autotransplantation, 32 of the 38 teeth contained nerve fibres travelling in the ipsilateral inferior alveolar nerve but, compared with normal, the fibres had decreased conduction velocities and produced small amplitude compound action potentials in the teeth when stimulated. Seven of the reimplanted teeth contained nerve fibres travelling in the contralateral inferior alveolar nerve. These results suggest that reimplanted and autotransplanted teeth may be reinnervated but the axons are small in diameter, and either few in number or mainly located near to the apices of the teeth. Reimplanted teeth may be reinnervated by axons from the nerve which supplied them originally or by sprouting and ingrowth of axons from nerves supplying adjacent tissues.

Action Potentials↗

Emergency management of oral trauma in children.

Oral trauma continues to be a common pediatric emergency, accounting for 150 emergency room dental consultations per year at Children's Hospital in Boston. Children between the ages of 18 months and 2.5 years and between 8 and 11 years are most at risk. Recent advances in the management of these dental emergencies may help children and their families avoid the psychological and financial cost of infection or loss of primary and permanent teeth. Treatment of avulsions in the young permanent dentition remains a common problem, and a universally accepted approach to its management is still evolving. The use of a doxycycline immersion prior to reimplantation by the dentist may be helpful in preventing external root resorption. As always, the best therapy against dentofacial trauma is the pediatrician's support of preventive measures.

Child↗

[Therapeutic management of traumatic avulsion of permanent teeth].

Management of avulsed permanent teeth requires perfect knowledge of the different parameters influencing the short and mid-term and above all long-term prognosis. Based on a review of the literature and the analysis of 50 cases cared for in our unit enables us to propose, in accordance with the extra oral delay and the degree of dental maturation, a protocol for the different emergency situations. This clarification emphasizes the contribution of new preserving solutions which allow reimplantation delays up to 24 hours without effect on prognosis.

Ankylosis↗

Evaluation of the topical effect of alendronate on the root surface of extracted and replanted teeth. Microscopic analysis on rats' teeth.

The treatment of choice for tooth avulsion is replantation. The ideal replantation should be realized as quickly as possible, or at least, the avulsed tooth should be kept in an adequate solution to preserve the periodontal ligament attached to the root. If that is not possible, treatment of the radicular surface should be done in order to prevent radicular resorption. The purpose of this study was to test sodium alendronate as a substance for topical treatment of the radicular surface of avulsed teeth in an attempt to prevent the occurrence of dental resorptions. Fifty-four rat maxillary right central incisors were extracted and replanted. Group I--extra-alveolar dry period of 15 min, intracanal dressing with calcium hydroxide (CALEN, S.S. White, Artigos Dentários LTDA, Rio de Janeiro, Brazil) and replantation; Groups II and III - extra-alveolar dry periods of 30 and 60 min, respectively, immersion in 1% sodium hypochlorite for 30 min for removal of the periodontal ligament, washing in saline solution for 5 min, and treatment of the radicular surface with 3.2 mg/l sodium alendronate solution for 10 min. Intracanal dressing with calcium hydroxide and replantation followed. At 15, 60, and 90 days post-reimplantation, the animals were killed and the samples obtained and processed for microscopic analysis. The results indicated that sodium alendronate was able to reduce the incidence of radicular resorption, but not of dental ankylosis. No significant differences were observed regarding variations in the extra-alveolar periods among the groups.

Alendronate↗

Splinting of avulsed central incisors with orthodontic wires: a case report.

A case of an 8-year-old boy who met with a road traffic accident causing trauma to the body and face and extrusion of the upper central incisors is reported. Laceration, oedema and limited mouth opening indicated the use of general anesthesia. During intubation the right central was avulsed accidentally and the left central further luxated and rotated. The avulsed central was reimplanted and the other one derotated and stabilised with orthodontic wire and brackets. Twelve weeks later the patients teeth were firm, immobile, radiographically normal and responded positively to vitality test.

Child↗

Reimplantation and immediate loading of an accidentally avulsed beaded implant: case report.

We present a case of reimplantation of an accidentally avulsed beaded Endopore (Innova Corp., Toronto, Canada) implant. The technique of immediate splinting and pharmacotherapy is described together with the clinical and radiologic evaluation for reosseointegration. This single case of reimplantation with immediate functional loading would suggest that, contrary to the manufacturer's recommendation, the Endopore implants can be successfully loaded immediately, functionally or nonfunctionally.

Accidents↗

Investigations on a cell culture medium for storage and transportation of avulsed teeth.

Non-physiologic storage of avulsed teeth leads to a high incidence of root resorption, resulting in poor prognosis. This study investigated the suitability of specially composed cell culture media for storage of extracted teeth for up to 48 hours. Autoradiographic investigations revealed that the proliferative activity of periodontal ligament (PDL) cells of teeth stored in cell culture medium for up to 48 hours increased with storage time. Studies on proliferation of PDL cells after storage of teeth in different media for up to 24 hours demonstrated that the proliferative activity is dependent on the composition of the medium. Immunohistochemical investigations with markers for cell proliferation revealed that pulp cells of extracted immature teeth show numerous proliferations after storage for up to 24 hours in a special cell culture medium but few proliferations after storage in Hanks Balanced Salt Solution (HBSS). The investigations indicate that a special cell culture medium can preserve cell viability of PDL cells adhering to extracted teeth for at least 48 hours. The in vitro results are confirmed by a case presented: After storage of two upper central incisors for 36 hours in the cell culture medium the teeth could be successfully reimplanted after extraoral insertion of titanium posts into the root canal (auto-alloplastic reimplantation). Clinical and radiological follow-up examinations for 12 months revealed normal periodontal healing.

Autoradiography↗

The effects of different splinting times on replantation of teeth in monkeys.

The purpose of the study was to examine histologically the tissue changes affecting the teeth and surrounding structures after using both 7- and 30-day fixation periods on replanted teeth in monkeys. Eight adult male rhesus monkeys were used. The maxillary central and lateral incisors were extracted, treated endodontically, reimplanted, and temporarily immobilized with an interproximal acid-etch splint. The splints were removed at 1 week in half of the teeth and at 30 days in the other half. The monkeys were killed at 7 and 14 days, and at 1, 2, 3, 4, 5, and 6 months postoperatively. The results showed that replanted teeth that were splinted for 7 days recovered uneventfully, whereas the teeth that were splinted for 30 days demonstrated increased areas of root resorption and ankylosis. Thus, it is suggested that after tooth replantation the periodontium will repair rapidly with a shorter time of splinting (7 days). Extended splinting periods (30 days) seem to induce further root resorption and dentoalveolar ankylosis.

Animals↗

A retrospective clinical and radiologic study of teeth re-implanted following traumatic avulsion.

Re-implantation is the recommended therapeutic procedure following traumatic exarticulation of teeth though its long-term prognosis remains controversial. The purpose of the following study was to evaluate the periodontal healing of 33 reimplanted incisors lost after trauma. The sample, which included 24 upper and 9 lower incisors, was divided in two groups: 15 teeth were reimplanted within 1 hour (=Group A) and 21 teeth after 3 hours or more (=Group B). The reimplanted teeth were followed for different radiographic evaluation periods up to 5 years (mean=2-9 years). The results showed a high rate of periodontal healing in Group A (66.7%), while Group B demonstrated a high percentage (83.3%) of both inflammatory and replacement resorption. Thus, even if the whole sample was prevented from drying before reimplantation, the teeth were affected by different rates of root resorption. Among the various prognostic factors suggested by the literature, bacterial contamination during extra-alveolar storage seemed the most critical.

Adolescent↗

[Wire/composite splinting of traumatically injured permanent teeth].

For splinting traumatically loosened and/or reimplanter remaining front teeth wire splints are used which are fixed by means of composite substance, gluing technique. Kinds of employed splints are disclosed and the steps of the practical carrying out of splinting are described. Indications, advantages and disadvantages of its employment are discussed.

Adolescent↗

A radiographic evaluation of the response of previously avulsed teeth and partially avulsed teeth to orthodontic movement.

Orthodontic movement, as documented in this study, can be accomplished successfully in the case of completely avulsed and partially avulsed teeth which have been reimplanted. These teeth respond to normal orthodontic forces and duration of treatment time by conventional orthodontic techniques and retention. Apical root resorption does occur more readily in these teeth before, during, and after orthodontic treatment. Six of the eighty-one involved teeth were lost because of complete root dissolution. The involved teeth which were reimplanted immediately without pulpal treatment and their integrity protected as living tissue were successfully treated orthodontically with no known losses as of this writing. It will be interesting to observe the tissue response of these avulsed teeth in the years ahead. How will time and circumstances deal with these teeth?

Adolescent↗