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At least 343 records · Page 19Linked to original sources

[Retrospective analysis of the effect of vinpocetine infusion in ophthalmologic disorders].

Retrospective analysis of the effect of vinpocetine infusion in ophthalmologic disorders. The authors retrospectively examined the effect of vinpocetine infusion on various ophthalmological disorders. Based on the data of 280 patients they concluded that vinpocetine infusion has beneficial effects in numerous ophthalmologic disorders of vision and visual field. There was a clear difference regarding the response to treatment. Best results were achieved in diseases characterized by sclerosis, hypertonia and macular degeneration. The improvement was modest or progression was slowed in patients with nervus opticus ischaemia, glaucoma and myopia. These results are in accordance with the literature data. The beneficial effect of vinpocetine can be explained by the fact that the vessels of the eye are in direct connection with the cerebral circulation and hereby the circulation improving effect of vinpocetine could be effective. The neuronal effects of vinpocetine could also play a role at least in two ways. On the one hand by the direct effect exerted on the cells of retina (these cells are related to the neurons), and on the other hand by the improvement of the circulation and metabolism of the secondary visual cortex found in the occipital lobe (this effect is proved by PET studies).

Adult↗

Organic vs. psychogenic factors in visual dysfunction.

A 17-year-old black male first complained of a relatively acute visual loss in both eyes just weeks before his 15th birthday. Extensive evaluations provided no definite organic cause for the acuity drop from 20/25 in June 1983 to 20/200 in November 1983. A psychogenic etiology was suspected but never confirmed. To date, optical devices provide the only means in attaining maximum visual efficiency.

Adolescent↗

[Universal treatment of ophthalmic migraine].

It's about a therapeutic method, particular to the author, which gets its universality from an optic prescription with a prismatic aspect. The ophthalmic headache's crisis is caused, in fact, by a spasm of convergence on an unknown exophory of which the amplitude of fusion is satisfying, and the presence of which can only be seen with test under screen.

Convergence, Ocular↗

The California syndrome. Functional visual complaints with potential economic impact.

The records of 84 patients with functional visual loss (59 adults and 25 children) were reviewed over a six-year period. The patients were between 7 and 69 years of age. In the young patients, psychosocial problems relating to parental divorce, poor school performance and attention-getting behavior were common, while in adult patients, financial gain was present in 51 of 59 (86%) individuals. Over 90% of the claimed abnormalities related to the afferent visual system. Fifty-three percent of the patients had underlying organic problems with functional overlay. Inconsistent test results were the most reliable means of identifying the malingering patients. In California, both ophthalmologists and optometrists are able to declare a patient legally blind as well as visually disabled for the purpose of income tax, workers' compensation, and disability benefits. The potential financial impact of malingering patients is discussed.

Adolescent↗

A new version of the TVAS: a validation report.

The purpose of this study was to investigate the validity of a revised version of the Test of Visual Analysis Skills (TVAS). Data are presented from testing 198 subjects in two elementary schools with two versions of the TVAS and a second perceptual skills test (VMI). Within-age-group, between-school statistical comparisons strongly support the validity of the revised TVAS.

Adolescent↗

Visual and visual perceptual disorders in neurodegenerative diseases.

Optic neuropathy is reported to occur in 10-30% of patients, while retinopathy is characteristic of type III OPCA. The use of visual and visual electrophysiological tests in early diagnosis and classification is promising. The relationship between visual impairment and other manifestations of these diseases has not been explored.

Brain Diseases↗

Is there a need for binocular vision evaluation in low vision?

The purpose of this study was to determine the need for a binocular vision evaluation in the management of low vision patients. Thirty subjects were selected with visual acuities of at least 6/60 in each eye. Twenty-three had age-related macular degeneration as the primary ocular pathology and seven had various other ocular conditions. The binocular vision evaluation comprised: detailed history and symptoms with an emphasis on the occurrence of near vision problems; modified binocular vision assessment which included cover test at near, ocular movements, convergence, Bagolini glasses, horizontal vergence reserves and prismatic measurement of any observed anomaly. History and symptoms revealed horizontal and vertical diplopia, jumbling of print, asthenopia, intermittent blurring and print being too small. Binocular vision assessment revealed exophoria at near, manifest horizontal deviations, convergence insufficiency, and vertical muscle imbalance. These anomalies occurred either singly or in combination. The results indicate that there is a need for binocular vision evaluation in low vision in order to reveal near vision disorders that may be partly attributable to binocular vision anomaly and not solely due to ocular pathology. This information should facilitate the implementation of the appropriate course of optometric management for these patients.

Aged↗

Ion channels-related diseases.

There are many diseases related to ion channels. Mutations in muscle voltage-gated sodium, potassium, calcium and chloride channels, and acetylcholine-gated channel may lead to such physiological disorders as hyper- and hypokalemic periodic paralysis, myotonias, long QT syndrome, Brugada syndrome, malignant hyperthermia and myasthenia. Neuronal disorders, e.g., epilepsy, episodic ataxia, familial hemiplegic migraine, Lambert-Eaton myasthenic syndrome, Alzheimer's disease, Parkinson's disease, schizophrenia, hyperekplexia may result from dysfunction of voltage-gated sodium, potassium and calcium channels, or acetylcholine- and glycine-gated channels. Some kidney disorders, e.g., Bartter's syndrome, policystic kidney disease and Dent's disease, secretion disorders, e.g., hyperinsulinemic hypoglycemia of infancy and cystic fibrosis, vision disorders, e.g., congenital stationary night blindness and total colour-blindness may also be linked to mutations in ion channels.

Animals↗

Clinical disorders affecting mesopic vision.

Vision in the mesopic range is affected by a number of inherited and acquired clinical disorders. We review these conditions and summarize the historical background, describing the clinical characteristics alongside the genetic basis and molecular biological mechanisms giving rise to rod and cone dysfunction relevant to twilight vision. The current diagnostic gold standards for each disease are discussed and curative and symptomatic treatment strategies are summarized.

Electroretinography↗