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[Prognostic value of the state of the heart atria in determination of the time of sinus rhythm preservation after correction of auricular fibrillation].

Data are presented from atrial vectorcardiograms of 130 patients with different forms of auricular fibrillation including an analysis of their parameters and a study of the catamnestic data following the elimination of auricular fibrillation, which permitted to develop prognostic criteria for determining the period of sinus rhythm preservation after this type of arrhythmia had been eliminated.

Adolescent↗

From rebellious palpitations to the discovery of auricular fibrillation: contributions of Mackenzie, Lewis and Einthoven.

An irregular pulse, referred to as rebellious palpitations, delirium cordis and pulsus irregularis perpetuus, was a cause of speculation by physicians since early times. It was James Mackenzie, a Scottish general practitioner in Burnley, England, utilizing an ink-writing polygraph to record and label jugular venous pulses, who would pioneer in deciphering normal and abnormal cardiac rhythms. His key observation that the jugular "A wave" was lost in a patient who went from a normal to an irregular rhythm provided the first insight into the mechanism of auricular fibrillation. Similar jugular venous and arterial pulse findings were discovered by Cushny, Edmunds and Lewis in directly observed experimental auricular fibrillation. In 1909 Lewis in England and Rothberger and Winterberg in Vienna, taking advantage of Einthoven's newly developed string galvanometer, were the first to establish electrocardiographically that auricular fibrillation was the cause of pulsus irregularis perpetuus.

Arrhythmias, Cardiac↗

Dicumarol and quinidine in the ambulatory treatment of chronic auricular fibrillation.

Thirty-three patients with chronic auricular fibrillation were treated with digitalis and quinidine and in addition were given Dicumarol(R) to reduce the risk of embolism. In 21 of the patients the fibrillation was caused by rheumatic heart disease, and in 12 by arteriosclerosis or hypertension. Normal sinus rhythm was restored in 55 per cent of the 33 patients, in 67 per cent of those with arteriosclerosis or hypertension, and in 45 per cent of those with rheumatic heart disease. Embolism did not occur.

Arrhythmias, Cardiac↗

Behaviour of the heart rate of horses with auricular fibrillation during exercise and after treatment.

Cardioversion through varying quinidine sulphate treatments was achieved in 3 riding horses with auricular fibrillation. The horses were subjected to continual telemetric ECG registration before and after reversion in a uniform exercise-tolerance-test. A comparison of the heart rate curves showed a strong decline of the heart beat frequency during the exercise phase after synchronisation. The decrease in heart rate during exercise was greater than 30% in all 3 patients. Anti-arrhythmic treatment is, therefore, recommended for horses with auricular fibrillation and without concurrent heart disease.

Animals↗

[Characteristics of oral anti-coagulation treatment in high-risk chronic auricular fibrillation].

OBJECTIVE: To calculate the prevalence of chronic auricular fibrillation (CAF), how much of it is considered high-risk (CAFhr) and the degree of coverage with oral anti-coagulation treatment (OAT). DESIGN: Multi-centre descriptive study. SETTING: 9 health districts. The "Terres de l'Ebre" Primary Care Service. PARTICIPANTS: Randomised sample of 375 patients with CAF, of whom 150 met the criteria of CAFh-r during 2002. MAIN MEASUREMENTS: Profile of patients with CAFh-r; coverage with OAT; place of follow-up; presence of vascular complications, and the time relationships between the diagnosis of CAF, vascular complications and the start of OAT. All the INR determinations taken from the patients included in the study were used. RESULTS: There was 2.2% prevalence of CAF (95% CI, 1.4-3.3). 40% of CAF had criteria of CAFh-r. 74.2% were treated with OAT. In 41.7% the diagnosis of CAF coincided with the incidence of some vascular complication. There were no differences between the overall results of the INR obtained in hospital and in PC. The expected efficacy of OAT for thromboembolism prevention in our high-risk sample was 61.12%. CONCLUSIONS: 40% of the CAF are high-risk. In over a third of patients OAT was indicated after a vascular complication linked to an unknown CAF. The INR between 2-3 is similar in PC centres and the corresponding haematology service.

Anticoagulants↗

[Possibilities of the automatic data processing in differential diagnosis of arteriosclerotic cardiosclerosis and rheumatic heart disease complicated by auricular fibrillation].

The possibility of applying some mathematical methods for automating the process of differential diagnosis between atherosclerotic cardiosclerosis and rheumatic heart diseases complicated by auricular fibrillation, based on employing computing technique in processing the cardiointervalographic findings, is discussed. The processing of cardiointervalograms taken in 2 groups of patients with diseases in question (totaling 49 persons) aged over 45 evidenced that in the differential diagnosis mathematical expectation and dispersion of the R-R intervals duration are most informative signs. It is shown that for the purpose of automatic diagnosis of atherosclerotic cardiosclerosis and rheumatic heart diseases complicated by auricular fibrillation with the method under discussion the sufficient length of cardiointervalograms equals 130--150 R--R-intervals.

Atrial Fibrillation↗

[The characteristics of digoxin utilization in a population under emergency care for heart failure or auricular fibrillation].

BACKGROUND: With the aim of studying the characteristics of the use of digoxin in a population which attended a hospital emergency department for heart failure or auricular fibrillation a 3 month observational study was carried out in the emergency department of the Ciudad Sanitaria de la Vall d'Hebron. METHODS: One hundred twelve patients treated with digoxin who went to the emergency department for heart failure and/or decompensated auricular fibrillation were studied. Clinical and pharmacological histories, determination of digoxinemia and the usual complementary explorations were performed. RESULTS: It was found that 50% of the patients were not adequately controlled and treatment was not followed in 21% of the patients. No significant relation was found between the doses of digoxin and the age of the patients. In multivariant analysis (multiple lineal regression) digoxinemia was related with the doses (beta = 0.22, p = 0.01), cardiac frequency (beta = 0.19, p < 0.05), and compliance (beta = 0.18, p = 0.05). Among the patients in whom the cause of decompensation of cardiac failure could not be identified, one third (31%) were found to have infratherapeutic digoxinemia. CONCLUSIONS: Most patients with cardiac decompensation attending an emergency department are those who are not adequately controlled in primary health care and the rate of incomplete following of the prescription is high. Furthermore, one third of the patients who decompensate with no clinically apparent reason has an infratherapeutic plasma concentration of digoxin.

Adult↗

[Electroimpulse therapy of auricular fibrillation].

Data derived from clinical, electro- and polycardiographic observations of 68 patients subjected to electric stimulation therapy are presented. The evaluation of late results of the treatment showed that clinical factors such as the patients' age, the nature of the affection, the degree of cardiac insufficiency, the standing of auricular fibrillation are not decisive in determining indications and contraindication for electric stimulation therapy. A considerable worsening of the cardiac dynamics with developing fibrillation arrhythmia, especially in patients suffering from cardiosclerosis, and a distinct improvement of the polycardiographic indices after defibrillation point to the need of attempting, whenever this is possible, to bar the auricular fibrillation. A pretreatment with potassium preparations and lengthy maintenance therapy with quinidine or quinidine-like agents is recommended. An analysis of the ECG findings after the electric stimulation therapy (heart rate, and its regularity, the state of the intraatrial and atrioventricular conduction) enable it to foresee the retention time of the re-established rhythm.

Adrenergic beta-Antagonists↗