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[Clinical studies on the use of ketalar in obstetric anesthesia (author's transl)].

26 healthy pregnant women at term were divided into 2 groups and anaesthetized with either 1 mg/kh or 2 mg/kg ketamine - N20/02 - for primary caesarean section. Maternal venous ketamine plasma levels, neonatal ketamine plasma levels (umbilical artery and umbilical vein) and blood gases were measured. Maternal venous ketamine plasma levels in group I exceeded those in group II by 2.8 (30-60 sec after injection) and 2.0 (at the time of delivery) respectively. Independent of the dose used, the plasma levels of ketamine in the umbilical artery or the umbilical vein were found to be identical in the two groups of newborn infants. Neonatal blood gases and acid base parameters did not significantly differ between the two groups, except for the oxygen tension in group II which slightly exceeded the PO2 values in group I 15, 60 and 120 min after delivery. pH and standard bicarbonate values were found to be higher (1 and 5 min) in both groups, compared to pH and standard bicarbonate levels in a group of newborns delivered spontaneously.--The results of this study show: 1. Independent of a low or high ketamine dosage, neonatal blood concentration of the drug remain low, probably due to a placental barrier effect.--2. The post partum recovery of the newborns was neither influenced by the ketamine anesthesia itself nor by different drug doses.

Anesthesia, Obstetrical

Obstetric anesthesia.

In this article, we have presented an overview of obstetric analgesia and anesthesia. If one central theme could be developed, it shoud be that analgesia either for labor and delivery or cesarean section must be chosen and performed with absolute exactness and safety. There is no margin for error. The ultimate goal should be delivery of obstetric anesthesia in such a way that the best qualified professional is responsible for establishing the services in the hospital. Such service must provide contiguous around-the-clock coverage for tertiary hospital centers. On the one hand, most anesthesiologists are not well suited to many of the special demands of the obstetric suite, and, on the other hand, many obstetricians lack the full understanding and capabilities that the anesthesiologists possess. One solution for this dilemma might be to encourage obstetric colleagues to seek anesthesia training in order to organize obstetric anesthesia coverage.

Analgesia

Obesity in obstetric anesthesia: A systematic review.

Maternal obesity presents complex challenges for anesthetic management, with implications spanning neonatal, cardiovascular, airway, neuraxial, and procedural domains. This review synthesizes evidence on how elevated maternal body mass index (BMI) impacts perioperative evaluations, risks, complications, and outcomes, in addition to anesthetic modalities and efficacy in the pregnant population. Given the increasing global prevalence of maternal obesity, anesthesiologists must refine clinical practices, employing tailored, evidence-based strategies to mitigate risks and enhance patient outcomes. This review aims to provide anesthesiologists and obstetricians with key considerations and best practices for managing obstetric anesthesia patients with obesity. Clinical recommendations herein are based on current research and evaluated using Oxford Centre for Evidence-Based Medicine for level of evidence and class of recommendation.

Humans

[Propanidid-ketamine combination in obstetrical anesthesia].

The A. have introduced a new technique in obstetrical, anaesthesia for short and long term intervention, included caesarean section, inducing anaesthesia with a mixture in the same syringe of propanidid and ketamin. The A. exhibit the results they have got treating the first 100 patients in this way and conclude with an extremely positive judgement.

Adult

Flaccid paraparesis following obstetrical epidural anesthesia: possible role of benzyl alcohol.

Severe flaccid paraplegia accompanied by extensive sensory loss after epidural anesthesia administered for labor and delivery occurred in a previously healthy 24-year-old primagravida. Recovery was virtually complete after 16 months. The cause of the neurologic deficits may have been the 1.5 percent benzyl alcohol preservative contained in an 0.9 percent saline solution used for postdelivery epidural injection.

Adult

[Continuous lumbar peridural anesthesia in obstetrics].

Review of 1000 continuous peridural anesthesias during labor and delivery. Reasons and conditions for the application of this analgetic procedure in our delivery rooms are discussed. The duration of labor and delivery is reduced by this method. The rate of vacuum extraction and forceps delivery is slightly increased. The rate of cesarean section is independent of this procedure. No adverse effects on the fetus were found. We obtained complete analgesia in 93 per cent of the cases. Severe complications were not observed.

Anesthesia, Epidural