PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “BLOOD DISEASES”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources
PubMed1977

[Blastogenetic activity of medullary blood serum of patients with various blood diseases].

Peripheral blood lymphocytes from 24 patients were cultured in vitro in the presence of autologous peripheral serum and bone marrow blood serum, with and without PHA stimulation. Bone marrow serum showed a well defined effect, in the absence of PHA stimulation, on lymphocytes from 4 patients (2 affected by acute leukaemia, 1 by megaloblastic anemia and 1 by benign idiopathic paraproteinaemia), and a less defined effect on lymphocytes from 2 donors (1 affected by iron deficiency anemia and 1 by thalassemia minor). No difference attributable to the source of blood serum was observed in PHA stimulated cultures. These results do not allow defined statements. Peripheral blood lymphocytes cultured in vitro were affected by bone marrow blood serum only in some subjects. A clear cut correlation between this effect and the clinical features of our patients was not evident.

Anemia, Megaloblastic↗
PubMed1982

The spin-lattice relaxation time in the blood of healthy subjects and patients with malignant blood disease.

To establish which constituents of blood influence the NMR relaxation time T1 of water protons in malignant blood diseases, 55 blood samples were studied (20 from healthy donors and 35 from patients with leukaemia, myelofibrosis and multiple myeloma). Relaxation time measurements were performed at 19.8 MHz resonance frequency and at a temperature of 33 +/- 1 degree C. There is a significant elevation of T1 over the normal level in whole blood, packed cells, and plasma of patients with blood disease. The relaxation rate R1 (= 1/T1) depends very strongly on the ratio of dry solids to water, which is in accordance with the three-state fast-exchange relaxation model.

Blood Physiological Phenomena↗
PubMed2002

The diagnosis from the pathological viewpoint of a blood disease.

The histopathological viewpoints of a blood diseases are namely following the cytological examinations except for the viewpoint of organ pathology and has been required only the usefulness in case with the difficulty of cytological examination. If it looks at a blood disease as hematopoietic organ disease, histopathological diagnostic study might make the new paradigm of blood diseases. In this time, I would like to present the hematological diagnosis from the pathological viewpoint by using histological bone marrow sections. *How to examine the bone marrow histology *Hematopoietic microenvironment disorder *Differential diagnosis of hypoplastic marrow lesions *Clinicopathological characteristics of Hypoplastic leukemia *Hemophagocytosis in bone marrow *How to diagnose MDS by histopathology. Bone marrow histology is the valuable diagnostic tool of many kinds of marrow disorders especial cases. By using immunohistochemistry and Giemsa staining, further information might obtain than smear film cytology. Bone marrow clot section aspirated from sternum is enough for histological examination except bone marrow biopsy. Precise cytomorphology might demonstrate by smear film than section histology. However surface phenotype would define by flow cytometric analysis, immunostaining of sections could demonstrate which cells show which markers. Structural and architectural disorder could only be represent by histology. The histological examination of bone marrow might introduce a new aspects of blood disease.

Aged↗
PubMed1992

[Rapid diagnosis of tuberculosis by amplification of mycobacterial DNA in blood diseases].

In patients with malignant blood disease, infection is the most serious complication. The prompt differential diagnosis of tuberculosis leads to an appropriate treatment. A method based on DNA amplification and hybridization for the rapid detection of Mycobacterium tuberculosis was used to test 10 clinical specimens (sputum, gastric aspirate and pleural effusion) from blood disease patients in whom tuberculosis was suspected. Mycobacterium tuberculosis DNA was detected in 3 specimens, including one which was negative on standard microbiological criteria (microscopy and/or culture). The other 7 specimens with fever or abnormal shadow on a chest X-ray were negative by both our method and the Standard microbiological criteria. Rapid diagnosis of tuberculosis by amplification of mycobacterial DNA in cases of blood disease in clinically useful.

Aged↗
PubMed1999

[Localized gene of the rare "Norrland disease". CDA-III blood disease with dominant heredity].

The article consists in a review of available knowledge of the rare blood disorder, congenital dyserythropoietic anaemia, type III (CDA-III), a disease characterised by autosomal dominant heredity, and mild to moderate haemolytic anaemia. The gene causing CDA-III has been localised on chromosome 15q22. Most patients are adapted to their disease, and have few or no overt manifestations. Bone marrow examination yields a characteristic picture of erythroid hyperplasia and multinucleate erythroblasts. A Swedish family affected with CDA-III has been reported to be characterised by a high prevalence of monoclonal gammopathy and angioid streaks, a triad suggested by the authors to represent a hitherto unreported syndrome.

Anemia, Dyserythropoietic, Congenital↗
PubMed1990

[An investigation into the actual condition of children with blood diseases in the pedodontic clinic of Niigata University Dental Hospital].

Children with blood diseases do not infrequently visit the dental clinics. Therefore, it is important to recognize the actual condition of blood diseases in association with the oral treatment of patients. During the period from Sept. 1979 to June 1989, 68 patients who had blood diseases visited the Pedodontic Clinic of Niigata University Dental Hospital. This report is the investigation of the dental situation of these patients. The result were as follows: 1. The ratio of patients with blood diseases in our clinic was 0.7%. The patients with leukemia were most frequent. 2. Most of the first visit-patients with blood diseases were children aged 6, while the general patients group was younger. The ages of first visit-patients corresponded to the most frequent ages of primary diseases. 3. The majority of their chief complaints were "the treatment of decayed teeth for caries". Others were "the extraction of loose teeth for exchange" or "the diseases of oral soft tissues". 4. The patients visited our clinic from all over Niigata prefecture, some of which visited from a great distance and were introduced by Niigata University Medical Hospital. 5. As to the treatment of decayed teeth for caries, the patients with hemophilia had a large number of treated teeth as compared with the other diseases. In case of leukemia, anaphylactoid purpura and idiopathic thrombocytopenic purpura (ITP), the outpatients generally tend to be subject to more severe caries than the inpatients in Niigata University Medical Hospital. 6. The percentage of recall of patients with blood disease was lower than that of general children at the rate of about 20%.(ABSTRACT TRUNCATED AT 250 WORDS)

Blood Coagulation Disorders↗
PubMed1958

Blood diseases.

Explore the source record for details and available documents.

Hematologic Diseases↗
PubMed1960

Blood diseases.

Explore the source record for details and available documents.

Hematologic Diseases↗
PubMed1961

Blood diseases.

Explore the source record for details and available documents.

Hematologic Diseases↗