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After the foundation of the course of pharmaceutical studies at Masaryk University in Brno in 1945, its Institute of Pharmaceutical Chemistry has been founded. In pharmaceutical chemistry, which was divided into the theoretical, synthetic and control-analytical parts, a system of classification was worked out based on classification of drugs according to the kind of effect for which it serves. This conception was incorporated into three editions of the book Chemická léciva (Chemical Drugs). The research programme of the Institute solved the development of novel local anaesthetic and antituberculous agents. After the disestablishment of the Faculty of Pharmacy in Brno, the development of pharmaceutical chemistry, continued at the Department of Pharmaceutical Chemistry, Comenius University, Bratislava, and beginning with 1969 at Charles University Faculty of Pharmacy in Hradec Králové.
The first known document on epilepsy in China appeared in The Yellow Emperor's Classic of Internal Medicine, Huang Di Nei Ching, written by a group of physicians around 770-221 B.C. The description of epilepsy in this book and in many others later published was confined to generalized convulsive seizures. No documentation of absence or simple partial seizures was provided. The first classification of epilepsy, probably by Cao Yuan Fang in A.D. 610, listed five types of epilepsy: "Yang Dian," "Yin Dian," "Feng (Wind) Dian," "Shih (Wet) Dian," and "Lao (Labor) Dian." Later, other classifications named seizures after the cry of animals whose cry the "epileptic cry" resembled, or after "visceral organs" believed to be responsible for the seizures. The concept of partial versus generalized seizures, however, was not observed in any of these classifications. The treatment of epilepsy, based on principles of "Yin Yang Wu Xing," consisted of herbs, acupuncture, and massage.
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The influence of George Gaylord Simpson (1902-1984) on paleoanthropology provides a well-documented, historical example of how one scientific discipline can impact upon another, bringing the latter quickly "up to speed" without having to retrace ground covered by the former. Paleoanthropologists were bystanders during the formulation of the evolutionary synthesis (1936-1947). After World War II, the younger paleoanthropologists looked to George Gaylord Simpson as one of several mentors regarding the implications of the synthesis for their own discipline. But why Simpson? Having earlier defined the superfamily Hominoidea (1931) as holding the Pongidae and Hominidae and monographed lower primate fossils (e.g., "Studies on the earliest primates," 1940), Simpson's "Principles of classification and a classification of mammals" (1945) further solidified his reputation as a mammalian systematist. Simpson's Meaning of Evolution (1949) was widely read as an introduction to the synthesis, and his Tempo an Mode in Evolution (1944) made accessible the more complex aspects. Consequently, in the 1950s and 1960s paleoanthropologists invited Simpson to participate in their symposia (e.g., "Some principles of historical biology bearing on human origins," 1951; "The meaning of taxonomic statements," 1964), used his books as classroom texts, and cited his publications to support claims for their own work. Later in the 1960s, Simpson moved from mentor to apologist, as the paleoanthropologists were by then familiar with the synthesis and incorporated its theoretical concepts in their interpretations of the many newly discovered hominoid fossils. Simpson now took special care to celebrate these results in his more general, less technical writings, acting as a forceful apologist for the materialistic view of human origins (e.g., "The biological nature of man," 1966; "The evolutionary concept of man," 1972). During the 1970s, Simpson's influence waned, and he became just another practitioner at the margin of the discipline. However, anthropologists acknowledged Simpson's earlier impact, for example, when he was invited, yet again, to address them at the 50th anniversary celebration of the American Association of Physical Anthropologists in 1981.
In this book, written in collaboration with Heidegger, Medard Boss endeavours for the first time to use Heidegger's late philosophical oeuvre as a basis for medicine and psychology. Boss attempts to uncover behind the understanding of man as existence, which prevail in "Sein und Zeit" and which has been so influential for Binswanger's existential analysis, a more original understanding of man as eksistence, as "open disponibility" (Offenständigkeit). The interest of this view resides in the resulting general principle of classification and interpretation of all forms of disease, giving rise to an "existenialistic pathology". The problematic aspect consists in the failure to integrate the "being-onself" in the understanding of human existence as open disponibility, which leads to a one-sided interpretation of disease processes.
The Year Book of Dentistry appears annually, providing a review of dental articles. We surveyed the abstracts of the recent 5 volumes of the Year Book of Dentistry, from 1985 to 1989. Two hundred and eighty articles were abstracted in each volume, divided into about 13 categories. The proportion of abstracts concerned with drugs and drug therapies (here termed drug information) was almost 20% in all volumes. Most of the drug information appeared under the heading "Oral Medicine and Oral Pathology" (63%). The original articles for the abstracts were from many journals, but 70% of the drug information articles were from JADA, Oral Surgery, and 10 other journals. The classification of the drugs in the drug information were: drugs for dental treatment, antibacterials, antiinflammatories, hemostatics, anesthetics, and others. Oral manifestations of systemic diseases or side effects of drugs used for these diseases were also abstracted. There were numerous articles of systemic diseases, due to dental treatments, including infective, hematologic diseases.
The goal of any social/health intervention program is to improve the lot of the people it is designed to serve. Of critical importance is the development and implementation of programs able to achieve such a goal is evaluation research (ER)--a process representing an interface between the generic notion of evaluation and the rigor of social research methodology. The evaluation researcher should be familiar with, and be capable of using, any of a number of (statistical and non-statistical) data-analytic techniques. The objectives of this discussion, therefore, are to (1) identify, categorize, and briefly describe statistical and other data-analytic techniques of potential use to the evaluation researchers; and (2) identify currently available resources, i.e., texts, books of readings, monographs, etc., that offer discussions and analyses of these techniques. It is hoped that such an exposition will lead to a wider understanding, acceptance, and use of these procedures, which can only enhance the quality of subsequent program policy- and decisionmaking.
For the first time in the Ninth Revision of the International Classification of Diseases (ICD-9) the chapter on mental disorders contained short glossary definitions for each category. A number of changes in attitudes and policies at the international and national levels, particularly the reorientation of mental health programmes to include behavioural and psychosocial problems, came at an opportune time and had a positive influence on the development of proposals for the chapter on mental and behavioural disorders in the Tenth Revision (ICD-10). This in turn enabled WHO to undertaken an intensive and extensive assessment of international needs in the classification of mental disorders and, where the situation was not unequivocal, to organize field trials to provide the empirical data necessary for problem solution. The result is a series of compatible classifications of mental and behavioural disorders based on ICD-10. The first, produced mainly as a reference tool for statistical purposes, will be included in ICD-10 with short glossary definitions as was the case for ICD-9. Other versions will be published for practising clinicians (with enhanced glossary definitions followed by diagnostic guidelines) for research (with full definitions, diagnostic guidelines and diagnostic criteria); for use in the provision of services to the mentally ill; and for use in general health (primary) care. There will also be a multiaxial classification of mental disorders in children to identify the clinical syndrome, resulting disability and environmental factors. It is hoped that these versions tailored to the needs of different groups working in the field of mental health will result in further improvements in communications between those responsible for the provision of services and care.
Perinatal deaths occurring over a seven year period were studied in a teaching hospital in Punjab. Causes of death were analysed as per Wigglesworth's classification. We have further modified this by correlating different gestations and weight groups with causes of death. The perinatal mortality rate (PNMR) in the present study was 74/1000 and showed a downward trend secondary to a statistically significant fall of early neonatal mortality. There was a decline in PNMR among babies of 1500-2000 g. birth weight and 33-36 weeks gestation. Asphyxia and macerated still births were found to be the two main causes of death. Macerated still births were seen more commonly among babies of lower weight at all gestations. The PNMR of babies born to booked mothers was 22/1000 as compared to 152/1000 among unbooked mothers. It was concluded that to bring down the PNMR, economic development alone is not enough. Provision of adequate antenatal care to all mothers, health education and timely referral of high risk mothers is very essential.
A brief outline is given of how various types of adaptation of the ICD for use in different situations have arisen. The application includes condensed lists, national adaptations, studies of morbidity, specialty adaptations (including for primary care), and augmentation by supplementary material. The major purposes of different applications are reviewed and an indication is given of factors influencing selection of the condition of primary interest in such situations. The article concludes by suggesting guidance for the development of applications and adaptations of the ICD.
In 1986, the U.S. Commission on pornography reviewed 3,050 separate magazine and book titles sold in "adults only" pornographic outlets randomly selected in Washington, DC; Baltimore, MD; Miami, FL; Philadelphia, PA; New York, NY; and Boston, MA. Of these, 746 titles could be assigned to a DSM III-R paraphilia category (513 titles if the category partialism is excluded). Incest was listed as a category separately from pedophilia. Thus, 16.8 percent of the titles could be assigned to a paraphilia category (24.4% of all titles, if partialism is included as a category). Paraphilia distribution is discussed. Sadomasochism was by far the most common paraphilia (49.9%) while incest titles comprised 21.4 percent of the perversions. The frequency distribution for the U.S. material is compared with titles reviewed by the Victoria (Australia) State Classification of Publications Board and previously reported by the author.
After less than four decades, the field of family therapy has largely abandoned the search for a typology of interaction between persons or between groups. Granted no single typology can conceivably fathom the hyper-dimensionality of human interaction. However, mankind's earliest recorded efforts to explicate the structures of human family systems are perceived by examining two of the earliest books known to man. These documents, The Book of Genesis of The Old Testament and the ancient Chinese Book of Changes or I Ching, can be viewed as loosely integrated modules of a single framework that help explain one another. The author suggests that these linked, family oriented sources also were the basis of modern symbolic logic and information (or switching) theory. Together they can provide the foundation of a hyper-dimensional meta-typology of human interaction. This could integrate interactions at and between levels of neuronal synapses and networks, the cerebral hemispheres, self and other, family and disparate social systems, and various human groups, national, racial, ethnic or religious.
International monitoring of the ICIDH has begun in earnest. The momentum from these new activities and organizations has worked towards the unification and harmonization of statistics and information devoted to the study of disablement, further enhancing the interdisciplinary nature of the study of disability and advancing its recognition both at the national and international level. This article introduces the reader to the definitions and concepts of the ICIDH. In addition, problems confronted when applying the ICIDH in policy formulation, programme implementation and evaluation and in research are reviewed. There are three main types of problem: (i) the difficulty in differentiating each of the concepts of impairment, disability and handicap at the operational level of human function and behaviour; (ii) the diversity of training and instructions required in order to orchestrate the use of the codes and classification schemes with persons having a wide range of expertise and analytical interests; and (iii) the need for consistency of use of the ICIDH for model-building and testing of different theoretical frameworks. Increased institutional development at the global level through the establishment of international networks, and regional and interregional programmes, have further clarified strengths and weaknesses of the ICIDH and have increased support of its use. These efforts suggest the increasing importance of the ICIDH for the future development of international statistical standards and recommendations in the field of disablement.
The International Classification of Impairments, Disabilities and Handicaps (ICIDH) has had a considerable impact on perception of the consequences of disease, and of the modifications which these consequences can present. Ideally, ICIDH is at the same time a descriptive, an explanatory and an implementation too for health policy. Two examples of the conceptual and policy use of ICIDH are given: policy developments proposed to Member States of the Council of Europe; multisectoral development in Québec. Both these examples underline that the ICIDH not only deals with clarifying items, but is also a support to the development of responsible policies.
The Tenth Revision of the International Classification of Diseases (ICD-10) will include two new definitions concerning death related to pregnancy: --Late maternal death--the death of a woman from direct or indirect obstetric causes more than 42 days but less than one year after termination of pregnancy. --Pregnancy-related death--the death of a woman while pregnant or within 42 days of termination of pregnancy, irrespective of the cause of death. This article discusses the rationale underlying these definitions and their implications for public health statistics. The introduction of these definitions is a step, albeit a timid one, towards an increased acceptance of epidemiology in determining the relationships which affect death related to pregnancy. It is to be hoped that the trend thus initiated can be encouraged.