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At least 37 records · Page 2Linked to original sources
PubMed2004

[Pharmaceutical chemistry of general anaesthetics].

The paper represents the first part of a planned series of reviews about pharmaceutical chemistry of drugs acting on the central nervous system. The authorial aim and editorial concepts are the same were followed in a former series of papers about pharmaceutical chemistry of agents effecting the heart, blood circulation and vegetative nervous system. Consequently, general anaesthetics are discussed in the present paper through the chapters "history, preparation; structure-properties-activity; application; analysis".

Anesthetics, General↗
PubMed1997

[Luigi Guerri, an ordinary pharmacists who became the "first son" of pharmaceutical chemistry].

Luigi Guerri (1823-1892) was one of the most important researchers and teachers in pharmaceutic chemistry in Florence in XIX century. Born and lived in Florence, patriot and colleague of the famous Ugo Schiff, from whom he received much praise, Guerri taught and carried out research into chemistry for about forty years at "Istituto di Studi Superiori" in Florence. This article is a synthesis of his career which started as first assistant to professor Campani, then he became a full professor, teaching pharmaceutic chemistry and eventually became the director of the pharmaceutic laboratory in "Arcispedale Santa Maria Nuova". This article, with the reproduction of some of Guerri's publications, shows the integrity of the man as a chemist and as a teacher. He was commemorated by Schiff and the scientific journal "Orosi" at his death.

Chemistry, Pharmaceutical↗
PubMed1986

Recent advances in pharmaceutical chemistry--review II. Histamine H2-receptor antagonists.

The concept of histamine receptors is outlined and the rationale for the synthesis of H2-antagonists presented. Structure-activity relationships among these compounds are described and aspects of absorption, distribution and elimination discussed with particular reference to cimetidine and ranitidine. Oxmetidine, lupitidine and loxtidine are also considered. Methods for the analysis of these drugs in body fluids are presented followed by a discussion of their toxicology. Volunteer and patient studies are also surveyed.

Animals↗