SEARCH · PubMed Health

Results for “Chlorpropham”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources

PubMedDate not supplied

The carry-through of residues of thiabendazole, tecnazene and chlorpropham from potatoes following manufacture into potato crisps and jacket potato crisps.

Potatoes, commercially treated with thiabendazole, tecnazene and chlorpropham, were processed into potato crisps and jacket potato crisps at a crisp factory using standard manufacturing conditions. A multi-residue method based on gas chromatography with mass spectrometric detection was developed and used to determine pesticide residue levels in the potatoes and potato crisps. Results showed that the residues of all three pesticides were significantly reduced to less than 2% and less than 10% of the maximum theoretical residue carry-through level for potato crisps and jacket potato crisps respectively.

Chlorpropham↗

PubMed2002

Study of potatoes' sprout inhibitor treatments with chlorprophame.

Studies carried out in 1999 by the University of Ghent showed that 36% of potatoes' samples contained Chlorprophame (CIPC) residues and that 7.9% of them exceeded the maximal limit of residues (RML), fixed at 5 ppm. The heterogeneity of sprout inhibitor application would be one of the causes of over-dosage. However, this heterogeneity would also cause under-dosages leading to problems when controlling the sprouting in potatoes stored over 6 degrees C. This study aims at determining some technical causes of the heterogeneity of CIPC sprout inhibitor treatments when storing potatoes. The study concerns two treatment techniques: dusting and spraying. To draw up an inventory of mechanical treatments in Belgium, a survey has been conducted among 28 farmers throughout Belgium. 35 samples have been taken at random in the different storage rooms to analyse the content of CIPC residue. In order to do so, a method of analysis: the gas chromatography in capillary phase with detection by mass spectrophotometry, has been developed. Tests have been carried out by changing several parameters such as the material, the product or the place in the storage line, in order to assess the CIPC application techniques. The survey made it possible to analyse qualitatively, from the declarations of farmers, the causes of heterogeneity linked to treatment techniques. An almost systematically over-dosage of the CIPC quantity has been noticed. However, out of the 35 samples analysed, only 2 had residue contents higher than the RML. The comparative analysis of the quantities applied and the residues contained in the samples made it possible to quantify the heterogeneity of the applications depending on the techniques. The tests carried out show in a general way that mechanical dusting, even though having a less constant flowrate than sprayers, leads to less important variation of the residue between samples. In testing conditions, the heterogeneity of the antigerminative treatment decreases when applied by means of a mechanical duster. In practise, these results are distorted by topical applications of CIPC. The combination of this practise with a too high heterogeneity of the treatment are to be avoided in order to have a good preservation and meet the residues standards.

Belgium↗

PubMed2003

The heterogeneity of sprout inhibitor application with chlorpropham.

The CIPC or chlorpropham is used on potatoes as "sprouting inhibitor". These lasts years, some set of belgian potatoes treated by CIPC exceeded the Maximum Residue Limit (MRL), fixed at 5 mg/kg. The heterogeneity of sprout inhibitor application would be one of the causes of over-dosage. In order to estimate the distribution of CIPC between potatoes, according to the formulation used (DP, EC and HN), a research project financed by "le fond budgétaire des matières premieres" has been set up. In order to evaluate the distribution of CIPC into the pile of potatoes, the efficiency of the different formulations as well as the residues caused by their application on tubers, some tests have been placed in the storage hall. These tests consist in taking off some samples at different places into the pile of potatoes during storage and destocking. The content of CIPC is analysed by capillary gas chromatography with detection by mass spectrometry detection (GC-MS) or nitrogen specific detection (GC-NPD). To estimate the efficiency, the sprouting are observed every month and samples of potatoes are taken off on the top of the pile to control the evolution of CIPC content. Considering the results of the tests, the inhibitor treatment with the formulation DP+HN seems to be the more efficient. As for the residues, the formulation DP leads to a higher content of CIPC than HN, that has a very low concentration. After treatment, the quantity really applied on tubers depends on the formulation used. In fact, 50% of CIPC applied by DP formulation are found on tubers but hardly 10%, after gas application.

Belgium↗

PubMed1981

[Effects of propham and chlorpropham on the embryonic development of various vertebrates].

The effect of propham and chlorpropham on Amphibians embryonic development changes with doses as well as species. The action of C.I.P.C. is always determinative. The egg poisoned in albumen involves important chick embryo malformations, but the development is stopped by the yolky vesicle poisoning. The intraperitoneal injection of C.I.P.C., strongly disturbs fetus physiology in Mouse.

Animals↗

PubMed1995

Effects of modulation of sulphation and glucuronidation on chlorpropham metabolism and cytotoxicity in isolated rat hepatocytes.

After modulation of sulphation and glucuronidation, the relationship between the changes in metabolism and cytotoxicity of chloropropham (CIPC), a widely used herbicide, was investigated in isolated rat hepatocyte suspensions. Under physiological conditions, CIPC had a cytolytic effect, modified membrane permeability and reduced intracellular ATP level. CIPC was metabolized by hepatocytes mainly into 4-OH chlorpropham sulphate (37%) and glucuronide conjugates (18%). Inhibition of sulphation, by omitting sulphate from the isolation and incubation media, did not affect the cytotoxicity of CIPC, since there was a 2.5-fold compensatory increase in 4-OH CIPC glucuronide. Inhibition of glucuronidation by adding 4 mM D-galactosamine in the incubation medium led to a 66% decrease of glucuronide conjugate and simultaneously to a 32% decrease of sulphate conjugate. In that case, concentrations of free 4-OH CIPC in both hepatocytes and incubation medium were markedly increased, while those of 3-chloroaniline and 3-chloroacetanilide were slightly modified and remained low. This alteration of metabolism was accompanied by modification of cell permeability and reduction in ATP synthesis. The cytolytic effect was due to CIPC itself, whereas the effect on energetic metabolism was attributed to a metabolite. Results demonstrated for the first time a partial inhibition of sulphation by D-galactosamine (4 mM), probably due to the effect of D-galactosamine on intracellular ATP levels.

Adenosine Triphosphate↗

PubMed1974