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Four cases of long-standing diarrhoea and colic pains cured by fructose-free diet--a pathogenetic discussion.

Four patients with a long history of abdominal swelling, colic pains and diarrhoea were cured by a fructose-free diet. They were all given an oral load of (14C) fructose and their expiratory excretion of 14CO2 was found to be significantly lower than that of control patients with similar symptoms. It is concluded taht the patients cured by a fructose-free diet might have a partial fructose malabsorption.

Adult

Crossed renal ectopia with colic. A clinical clue to embryogenesis.

A clinicopathologic correlation of 2 patients with crossed renal ectopia presenting with ureteric colic and 4 cases collected from the literature is presented. The correlation serves to reaffirm the theory of ureteral and not renal, migration as the primary aberration resulting in this defect.

Adult

The value of arterial blood pressure measurement in assessing the prognosis in equine colic.

Indirect arterial blood pressure was determined on 33 horses prior to surgical intervention for the diagnosis and/or correction of acute abdominal disorders and a relationship between low systolic blood pressure and non-survival was established. It is suggested that blood pressure determination should be used to augment other methods of clinical and laboratory examination in cases of equine colic.

Animals

[Nephretic colic in patients with arrhythmia (author's transl)].

The authors relate one case of obstruction by emboly in the renal artery. The diagnosis were too late for conservative surgery. In this case, they insist on the particulary signs of that nephretic colic and they show the diagnosis measures which are able to permit a conservative surgery in urgency.

Colic

Biliary colic as a model for assessing analgesic activity in man.

Acute pain from biliary colic is a model of pathological pain suitable for pharmacological investigations. It has been found useful for assaying analgesic effect of a narcotic-type agent (pentazocine) and a non-narcotic drug (indoprofen), both given intravenously in a single dose. Differences in pain intensity scores assessed on a five-point scale were taken as measurement of the pain-relieving effect. Distribution-free methods were used to estimate the potency ratio of the tested drugs. The analgesic potency of indoprofen based both on total and peak effect was roughly one-tenth that of pentazocine on a weight-for-weight basis. No adverse reactions were associated with indoprofen and a few were found after pentazocine.

Adult

Renal autotransplantation for recurrent renal colic.

Renal autotransplantation as an alternative to ileal interposition has been done successfully in patients with repetitive episodes of renal colic. Urinary tract continuity has been re-established by anastomosis of a Boari tube directly to the renal pelvis. This has resulted in easy egress of recurrent calculi without pain. Furthermore, the musculature of the Boari tube seems to be adequate for prevention of vesicorenal reflux. The procedure has been devoid of electrolyte and mucous urinary retention problems associated with ileal interposition and it is advocated as an alternative in the management of such patients when medical therapy fails.

Adult

Indomethacin in the treatment of ureteral colic.

Based on a theoretical analysis of the genesis of ureteral colic, it was assumed that indomethacin, a potent prostaglandin synthesis inhibitor, ought to be useful in the treatment of patients with an obstructing ureteral stone. Experimental studies and clinical observations have verified this assumption.

Animals

[Verminous enteritis and thrombo-embolic colic in the horse. A description of 36 cases (author's transl)].

Based upon case reports from 36 cases of verminous thrombosis of arteria mesenterica cranialis--all of which were verified at necropsy--clinical symptoms, course and pathological lesions are described. Seventy five per cent of the patients were under 3 years old, and 73% of the cases showed initial signs during the period July-December. Salient clinical findings were, unthrifty appearance and emaciation, diarrhoea--observed in two thirds of the patients--and colic--observed in 50 per cent of the cases. Haematological and biochemical findings were inconclusive, yet, hypoproteinaemia was a rather frequent finding. At necropsy, enteritis and/or typhlocolitis were observed in 29 horses of which 8 horses had superficial lesions, 7 horses hyperplastic lesions and 12 horses diphteroid/necrotizing lesions. Fourteen per cent of the horses had renal infarctions. The findings are discussed in relation to recent observations on the epidemiology of Strongylus vulgaris infection and comparisons are drawn to findings in a material of horses with non-parasitic enteritis.

Animals

Colic in the horse. A clinical and clinical chemical study of 42 cases.

42 horses were examined. The physical signs with relation to circulatory insufficiency and the abdominal disease were registered following a two-phased examination procedure. Great prognostic value was found in the degree of circulatory insufficiency judged by pulse rate and character, filling of the jugular vein, skin temperature, colour of mucous membranes, capillary refill time, sweating, depression, skin turgor and degree of enophthalmus. In making a causal diagnosis the abdomen was examined for shape, tenderness, peristaltic sounds, gastric dilation by siphoning, abnormal rectal findings and macroscopic changes in peritoneal fluid. Greatest diagnostic difficulties were encountered in cases of intestinal atonia, acute enteritis and torsion of the colon. In selected (severe) cases laboratory tests were obtained. Blood samples were examined for packed cell volume, hemoglobin, red and white blood cell counts, differential white blood cell count, blood gases and acid-base status, lactate, serum total protein and albumin, plasma sodium, potassium, chloride, calcium, magnesium, inorganic phosphorus, glucose, creatinine, BUN, total bilirubin, ASAT, CK, BASP and GGT. Peritoneal fluid was examined for red blood and white cell counts, total protein, specific gravity, pH and lactate, and enzymes as in blood. Laboratory results generally confirmed the clinical signs of shock, and packed cell volume and blood lactate were regarded to be of greatest prognostic interest. Although the performed laboratory information, macroscopic evaluation was thought to reveal sufficient information in most cases. It was concluded that supervening shock is of decisive importance in severe forms of colic, and that a careful and repeated evaluation of the circulatory insufficiency often provides one with a tentative prognosis although the final diagnosis is not obtained. In spite of therapy fatal outcome was found in all seriously shocked horses.

Abdomen, Acute

Case report: equine colic associated with sand impaction of the large colon.

In most cases the outcome of impaction of the colon is favourable and with mild purging and lubrication, the mass can be broken down and the horse returned to normal health. It is important to reevaluate impaction cases which neither deteriorate or improve in a 24 hour period and to perform a paracentesis to evaluate the etiology and prognosis. A decision of euthanasia or surgical correction should be made as early as possible. Though initially stable, vital signs will deteriorate rapidly without warning. A critical evaluation of the client's farm management can prevent many impaction colics and the service practitioners provide is not complete unless the necessary changes are made.

Animals

The crying baby--why colic?

All babies cry, but the mother unable to satisfy her infant's distress may experience doubts as to her own mothering ability. Yet 'colic' is often used to explain away many problems of the infant. But to accept such a diagnosis denies mother and infant help at this difficult time.

Colic

[Pramiverine/metamizole - a spasmoanalgesic for routine therapy of symptoms in emergency/a clinical trial in patients with biliary colics (author's transl)].

The authors refer to a previous trial with the combination 4,4-diphenyl-N-isopropyl-cyclohexylamine-hydrochloride (pramiverine Sistalgin) and N-methyl-N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-aminomethanesulfonate (metamizole) (Sistalgin comp.) in patients with renoureteral lithiasis and report results obtained with the same spasmoanalgesic and a comparative preparation in patients with biliary colics. On the basis of parameters selected for the trial, the success of pramiverine/metamizole therapy in subjective and objective complaints induced by biliary stone diseases is considered positive.

Adolescent

Colic as the sole symptom of urinary tract infection in infants.

Urinary tract infection was diagnosed in four infants whose sole symptom was persistent recurrent colic. There were no other clinical abnormalities. Three had abnormal radiologic findings in the urinary tract and one subsequently required nephrectomy. In the two others, radiologic findings were normal after 6 months and 1 year, respectively.

Colic

[Complications of a paranephric novocaine block for renal colic].

Under observation were 12 patients, in whom following paranephral novocain blockade subcapsular and paranephral hematomas, purulent paranephritis, abscesses and carbuncles of the kidneys developed. All patients were subjected to surgery. In such cases to eliminate renal colic it would be more safe to perform other kinds of theapeutic procedures (the injection of spasmolytic, the blockade after M. Ju. Lorin-Epshtein method, etc) which are not at all inferior in their effect to paranephral novocain blockade.

Adult

Seasonal variations in the incidence of ureteric colic.

A retrospective study of 1097 male in-patients with ureteric colic was conducted to try and define the aetiological effect of climate on the disease. The overall monthly incidence for the study period of 10 years was found, on statistical analysis to correlate with ambient temperature thus: (1) directly with the mean temperature of the preceding month, (2) directly with the difference between mean maximum and mean minimum temperatures of the same month, and (3) inversely with the mean maximum temperature of the same month. The correlation was interpreted on the basis that hot ambient temperatures promoted stone generation whereas cold ones promoted stone descent through cold-induced diuresis. This trend, among its other implications, could pinpoint the reason for the increase in nephrolithiasis with industralisation.

Adolescent

[Alcoholism, colic diverticular disease and metabolic disorders (author's transl)].

70 patients with colic diverticular disease and 50 control subjects were compared. Sexes and ages were matched in the two groups. Significant higher frequencies of alcoholism (P < 0,00001), hyperlipidemia (P < 0,0001), impaired oral glucose tolerance test (P < 0,001), hyperuricemia (P < 0,01) and atherosclerosis (P < 0,000001) were noted in the diverticular group. Hypothesis about pathogenesis of diverticular disease are suggested.

Adult

[Colonic perforation with special reference to spontaneous ileo-colic perforation].

Aetiology of colonic perforation is reviewed and discussed. 8 cases of "spontaneous" ileo-colic perforations observed between 1975 and 1977 are presented. Two of these patients had recently undergone appendectomy, and 4 others showed a simultaneous distal carcinoma of the large bowel. Histo-pathological evaluation did not reveal the cause of intestinal perforation. Operative treatment and results are given.

Adolescent