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At least 37 records · Page 2Linked to original sources
PubMed2006

The digestive system and nutritional considerations for individuals with Rett syndrome.

Rett syndrome (RS) is a neurodevelopmental syndrome of genetic origin that mainly affects females. Individuals diagnosed with RS exhibit a variety of functional difficulties that impair their quality of life. One of the affected systems is the digestive system, where 74% of persons with RS have abnormal functioning. The affected digestive system causes this population to present an array of problems, such as gastroesophageal reflux (GER), constipation, and malnutrition, leading to failure to thrive (FTT), which resolves in reduced functional ability. Due to the severe effects of the dysfunctional digestive system of individuals with RS, this article will describe the problems common to this population, as well as propose some clinical suggestions for intervention.

Comorbidity↗
PubMed1978

Pathology of centenarians. II. Urogenital and digestive systems.

The urogenital and digestive systems in 23 centenarians (7 males and 16 females) were examined pathologically. In the urogenital system, macroscopic scar formation, chronic pyelonephritis and arterio- and arteriolosclerosis of the kidney usually were pronounced. Six instances of prostatic glandular hyperplasia were demonstrated, and three of these were associated with well-differentiated adenocarcinoma. The testis, ovary and uterus usually showed a strong tendency toward atrophic changes. In the digestive system, senile atrophy of the liver and formation of colonic diverticula were noted. In this series of aged subjects, malignant lesions of the gastrointestinal tract were rare. It is also noteworthy that the unsuspected lesion of massive gastrointestinal hemorrhage associated with the various observed disorders might have been the cause of death in some of these centenarians.

Aged↗
PubMed2002

[Clinical analysis of 55 ovarian metastatic tumors from digestive system].

BACKGROUND & OBJECTIVES: Ovarian metastasis of digestive system tumors is a special way of tumor metastasis, which the diagnosis and treatment are difficult. The objective of this paper is to seek the clinical characteristics of ovarian metastatic tumors from digestive system, to aid correct diagnosis and treatment, so that to improve their curative effect. METHODS: The authors collected the information of 55 patients with ovarian metastatic tumors from digestive system, and analyzed 12 items of the patients including their age, menorrhea and child-bearing, details of original tumors and metastatic tumors, pathologic types, ascites, clinical symptoms, tumor markers, time of metastasis, diagnosis, treatment, curative effect, etc. RESULTS: Misdiagnosis rate of the team was 30.9%. Survival rate of 1 year, 3 years, and 5 years were 22.4%, 4.1%, and 2.0% in 49 patients, followed up respectively. CONCLUSION: Ovarian metastatic tumors from digestive system are easy to be misdiagnosed, and have poor prognosis. Careful long-term follow-up and active operation and chemotherapy may be effective to improve their curative effect.

Adult↗
PubMed2000

Biological clocks and the digestive system.

Circadian rhythms play a major role in regulating the digestive systems of many organisms. Cell proliferation, migration, differentiation, and even structure vary as a function of time of day in many different digestive organs (i.e., stomach, gut, liver, and pancreas) and cell types, resulting in regionally specific temporal variations in protein and gene expression. Feeding and light set the hands of the digestive clock(s). However, the clockwork has a genetic basis. During the last 10 years, new developments have emerged in our understanding of how cells keep time. Surprisingly, clock genes in mammals are expressed not only in specialized time keepers in the brain, but also in peripheral organs, suggesting that the ability to keep time may also belong to cells within the digestive system. This article reviews several classic examples of circadian variation in the digestive system, with an emphasis on rhythms in cell proliferation, function, and structure. It also briefly summarizes several new ideas about how cells in the brain and possibly the digestive system keep time.

Animals↗