A dithyramb to the dictionary.
Explore the source record for details and available documents.
SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
MOTIVATION: Automatically identifying protein names from the scientific literature is a pre-requisite for the increasing demand in data-mining this wealth of information. Existing approaches are based on dictionaries, rules and machine-learning. Here, we introduced a novel system that combines a pre-processing dictionary- and rule-based filtering step with several separately trained support vector machines (SVMs) to identify protein names in the MEDLINE abstracts. RESULTS: Our new tagging-system NLProt is capable of extracting protein names with a precision (accuracy) of 75% at a recall (coverage) of 76% after training on a corpus, which was used before by other groups and contains 200 annotated abstracts. For our estimate of sustained performance, we considered partially identified names as false positives. One important issue frequently ignored in the literature is the redundancy in evaluation sets. We suggested some guidelines for removing overly inadequate overlaps between training and testing sets. Applying these new guidelines, our program appeared to significantly out-perform other methods tagging protein names. NLProt was so successful due to the SVM-building blocks that succeeded in utilizing the local context of protein names in the scientific literature. We challenge that our system may constitute the most general and precise method for tagging protein names. AVAILABILITY: http://cubic.bioc.columbia.edu/services/nlprot/
Explore the source record for details and available documents.
Since biomedical texts contain a wide variety of domain specific terms, building a large dictionary to perform term matching is of great relevance. However, due to the existence of null boundary between adjacent terms, this matching is not a trivial problem. Moreover, it is known that generative words cannot be comprehensively included in a dictionary because their possible variations are infinite. In this study, we report our approach to dictionary building and term matching in biomedical texts. Large amount of terms with/without part-of-speech (POS) and/or category information were gathered, and a completion program generated approximately 1.36 million term variants to avoid stemming problems when matching terms. The dictionary was stored in a relational database management system (RDBMS) for quick lookup, and used by a matching program. Since the matching operation is not restricted to a substring surrounded by space characters, we can avoid the problem of null boundaries. This feature is also useful for generative words. Experimental results on GENIA corpus are promising: nearly half of the possible terms were correctly recognized as a meaningful segment, and most of the remaining half could be correctly recognized by some post-processing process, like chunking and further decomposition. It should be remarked that although we have not used term cost, connectivity cost, or syntactic information, reasonable segmentation and dictionary lookup were performed in most cases.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.