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PubMed2000

[Endoscopic treatment of iatrogenic esophageal perforation].

BACKGROUND: Esophageal perforations are the most frequent complications of endoscopy of the upper gastrointestinal tract. Life-threatening consequences such as mediastinitis, septic disease, or multiple organ failure are possible. Traditional surgical and conservative methods of treatment should be distinguished. In serious cases, thoracotomy in particular is a high-risk operation. PATIENTS AND RESULTS: This case demonstrates the successful endoscopic treatment of an esophageal perforation with mediastinal empyema by fibrin gluing. CONCLUSIONS: Esophageal perforations up to 20 cm aboral and a maximum diameter of 1.5 cm could be treated by rigid endoscopical fibrin gluing. High-risk patients could be managed effectively avoiding extensive surgery.

Aged↗
PubMed1981

[Lethal complications caused by perforating esophageal injuries (author's transl)].

Symptoms, complications, and pathoanatomic findings of three cases, in which the esophageal perforation originally caused the death, are demonstrated. The first case deals with an pressure-errosion as a result of gavage, the second an incised wound by a razor blade, and the third a through-and-through gunshot wound of the upper part of the esophagus.

Adolescent↗
PubMed2006

[Therapy and course of disease in spontaneous esophageal perforations].

INTRODUCTION: Esophageal perforations occur spontaneously or as a complication of endoscopic procedures. Especially in spontaneous perforation there is ongoing debate regarding the best treatment options. METHODS: 24 patients that were treated at two surgical centers (University Halle, City-hospital Bielefeld) after spontaneous esophageal perforations between 1996 and 2005 were analysed retrospectively. RESULTS: All patients but one underwent surgical treatment with in 2 cases additional stent implantation. Average stay in hospital was 53 days. In-hospital-lethality was 25% (overall lethality 37.5%). Concerning the therapeutic outcome there was no link between patients' age, localization or size of the perforation and the time interval between perforation and treatment. In 22 patients diagnosis was made > 12hrs after the event. CONCLUSIONS: Main problem of the Boerhaave-syndrome is the septic-toxic disease. Prognostic criteria are the patients' health-state and not factors like size of perforation, time of delay or localization of the perforation. Since in case of survival esophageal resection shows good long-term-results, in doubt a radical surgical procedure should be recommended as primary option. Implanting an esophageal stent might become a useful mean of treating patients with spontaneous perforations.

Adult↗
PubMed1977

Pediatric esophageal perforation.

Although esophageal perforation in children is associated with a spectrum of disease different from the one in adults, management is essentially the same for both groups. Over the past 11 years, 12 patients ranging in age from 2 days to 10 years were treated for 13 perforations. Perforation in the adult is associated with a high mortality rate. All children in this series survived. Injury was secondary to instrumentation in 10 cases and three resulted from the chronic erosion of a trapped foreign body. Of the 10 acute perforations, five occurred 12 days to 5 months after lye ingestion. Anastomotic narrowing was a factor in three other cases. Seven of the acute perforations involved the thoracic esophagus and were associated with a high morbidity rate. Management consisted of operative as well as nonoperative approaches. Consideration must be given to several clinical variables including location, cause, predisposing factors, underlying illnesses, associated injury, and promptness of medical attention.

Bronchial Fistula↗
PubMed1980

Esophageal perforation associated with the esophageal obturator airway.

The esophageal obturator airway (EOA) has been approved since 1973 as an adjunct for artificial ventilation. Description of the tube and contraindications to its use are presented. The two primary complications are tracheal intubation and esophageal perforation. A case report of esophageal perforation after EOA use is presented and a brief review of the previously reported cases is correlated with this case report. The true incidence of this complication has never been accurately studied but estimates vary between 0 and 2%. Possible factors contributing to this complication are discussed and recommendations regarding proper inflation are given. Because early diagnosis and treatment is essential, helpful historical, clinical, and radiographic findings that are presented should help to increase the index of suspicion of this complication. Increased familiarity with the EOA by physicians in the emergency department and the ICU is also necessary for early diagnosis and treatment.

Esophageal Perforation↗
PubMed1983

Esophageal perforation following use of esophageal obturator airway (EOA).

Esophageal perforation following use of the esophageal obturator airway (EOA) has been reported in a small number of patients. However, it has generally been discovered only in the presence of obvious clinical signs in patients otherwise resuscitated from cardiac arrest. Since it may well be overlooked in patients who succumb following the combined insult or primary cardiac arrest and secondary esophageal perforation, the true incidence of this adverse consequence of EOA use is unknown. We present a case of esophageal intubation with the EOA, and review in detail previous reported cases. We further suggest possible mechanisms leading to this catastrophic consequence of intubation with the EOA, and comment on its significance with regard to the controversy over EOA versus endotracheal (ET) tube training for paramedic pre-hospital personnel.

Adult↗
PubMed2000

Right-sided pleural effusion in spontaneous esophageal perforation.

Spontaneous esophageal perforation (Boerhaave's syndrome) is a rare clinical entity in which overindulgence in a large meal precedes vomiting and chest pain. Early diagnosis and aggressive management are keys to minimizing the morbidity and mortality. We report an unusual presentation of this already uncommon occurrence in a 33-year-old female. She presented to the Emergency Department with severe chest pain following vomiting with hematemesis after a large meal. The initial chest radiograph showed up nothing in particular. Dyspnea developed two days later, and a right-sided pleural effusion was seen on chest x-ray. Panendoscopy was highly suggestive of Boerhaave's syndrome. She underwent emergency operation. After three months of hospital care, she was discharged in relatively good condition. This case of right-sided pleural effusion extends the reported description of Boerhaave's syndrome.

Adult↗
PubMed1992

[Spontaneous esophageal perforation related to fungal esophagitis].

The authors give account of spontaneous esophageal perforation developed on the basis of fungal oesophagitis. The lesion of the lower third of the esophagus classified as grade 4. on Kodsi classification displayed the same picture as an advanced esophageal cancer. They review signs, symptoms and varieties in macroscopic appearance of esophageal candidiasis. They warn that in case of a spontaneous perforation of "malignant" esophageal tumor with no preceding signs the rare condition of fungal esophagitis must certainly be considered.

Adult↗
PubMed2004

Superimposed spontaneous esophageal perforation in congenital esophageal stenosis.

Congenital esophageal stenosis (CES) is a very rare embryologic anomaly of tracheoesophageal development that requires lifelong management, usually with frequent esophageal dilations and dietary precautions. We present a patient with spontaneous thoracic esopahgeal perforation in a setting of CES. The patient, a 27-year-old male, recovered uneventfully following open primary esophageal closure. A brief but comprehensive discussion of CES follows the case report.

Adult↗
PubMed1976

Esophageal perforation following use of esophageal airway.

The esophageal airway has gained increasing acceptance in airway management during cardiopulmonary resuscitation, and its enthusiastic advocates are urging expansion of its use. A fatal case of esophageal perforation following the use of an esophageal airway is presented. Possible contributing factors are discussed. A modified esophageal airway which seems safer and more versatile, effective, and economic is described.

Esophageal Perforation↗
PubMed1995

[Iatrogenic esophageal perforation in inoperable esophageal carcinoma. Its therapy with a plastic-coated metal stent].

A 60-year-old man was admitted to hospital because of severely impaired swallowing, retrosternal pain and marked weight loss. History and physical examination of the patient, whose general condition was obviously much reduced, pointed to carcinoma of the oesophagus. Contrast-medium swallow demonstrated subtotal stenosis in the oesophagus. Computed tomography and magnetic resonance imaging showed a space-occupying mass originating from the oesophagus, in close relationship to the trachea, main bronchi and descending aorta. Biopsy confirmed the diagnosis of oesophagus carcinoma and exploratory thoracotomy excluded curative surgical treatment. An attempt was made to introduce a feeding tube endoscopically to provide nutritional palliation. But the oesophagus was perforated during this manoeuvre and resulted in an oesophagobronchial fistula with subsequent mediastinitis and mediastinal emphysema. Using a self-expandable plastic-covered metal stent it was possible to cover the perforation and overcome the patient's dysphagia. The mediastinitis healed under intravenous administration of cefotaxim (2 g three times daily), netilmicin (400 mg daily) and metronidazole (500 mg three times daily), for 5 days.

Carcinoma, Squamous Cell↗
PubMed2007

[Management of iatrogenic esophageal perforations].

BACKGROUND: Iatrogenic esophageal perforations are still a life-threatening clinical entity. PATIENTS AND RESULTS: We present the case reports of six patients to demonstrate different treatment options and we focus on new therapeutic strategies which have evolved in the interdisciplinary management of iatrogenic esophageal perforations. Two patients with perforations in the cervical esophagus were operated and in another patient the perforation was closed with fibrin glue. Three patients with perforations in the thoracic esophagus were treated with self-expandable plastic stents. CONCLUSION: The surgical therapy of esophageal perforations still is regarded to be the gold standard and nonadherence should only be considered based on interdisciplinary decisions in individual cases. However, positive results are increasingly being reported for conservative endoscopic treatment, particularly for thoracic perforations.

Adult↗
PubMedDate not supplied

Esophageal stents as a salvage therapy for non-malignant iatrogenic esophageal perforations.

BACKGROUND: Esophageal non-malignant perforations are severe life-threatening conditions. The current treatment is either surgical or conservative. METHODS: We report a case series of 3 consecutive patients (1 female, 2 male; 34-68 years) treated with expandable covered stents for non-malignant iatrogenic esophageal perforations. OBSERVATIONS: In our series, 3 out of 3 patients sealed their perforations and resumed normal oral intake. Complications observed were 2 stent migrations, which occurred at 6 and 11 months after stent insertion, a stenosis due to acid reflux treated by another stent insertion above the first one. On the basis of the data available, it appears that esophageal stents was successful in 82% of the cases. The mortality and complication rates were of 7% and 32% respectively. The main complications observed were peptic stenosis above the stent and fistulas. CONCLUSION: These results are promising but need to be confirmed in large-scale prospective studies. Mediastinal drainage remains mandatory when sepsis is present.

Adult↗
PubMed1988

[Spontaneous esophageal perforation. Radiological diagnosis].

Esophageal perforations are rare and usually occur after instrumentation. We relate here a case unsuspected spontaneous esophageal perforation. Computed chest tomography firstly showed signs of mediastinal abscess. Secondary barium meal confirmed the diagnosis.

Esophageal Perforation↗
PubMed1992

Spontaneous esophageal perforation in herpes simplex esophagitis.

A 32-yr-old, previously healthy man with severe chest pain of sudden onset was found to have purulent pericarditis and pleural effusions. Several days later, an esophagogram revealed a perforation of the thoracic esophagus. Endoscopy showed a picture highly suggestive of a late stage of an extensive herpes simplex virus (HSV) esophagitis. Biopsies revealed evidence of massive HSV infection, confirmed by immune microscopy and virus culture. At surgery, a mediastinal abscess was found, and an esophageal perforation was identified. These findings suggest that the etiology of the perforation was an unusually severe herpetic infection. To our knowledge, HSV esophagitis has not previously been implicated as the cause of spontaneous esophageal perforation.

Adult↗
PubMed1988

Esophageal perforation following external blunt trauma.

Esophageal perforation from external blunt trauma is an exceedingly rare injury. Since 1900, including our five cases, we found 96 reported cases. The most common cause was violent vehicular trauma. The cervical and upper thoracic esophagus was the site of perforation in 82%. In 78% of the cases, there were findings consistent with esophageal injury, but there was a delay in diagnosis in two thirds of these. The diagnostic difficulty was due to lack of a specific symptom complex for esophageal perforation. Often esophageal perforation was not suspected and the symptoms were attributed to the more common injuries, or the diagnostic workup was incomplete. There were 24 (38%) infectious complications directly related to the esophageal perforation. In 21 of these, there was a delay in diagnosis. There were five (9.4%) deaths due to sepsis from the esophageal perforation.

Accidents, Traffic↗
PubMed1993

Esophageal perforation: CT findings.

OBJECTIVE: Esophageal perforation is a life-threatening condition that can be quickly diagnosed on the basis of findings on contrast esophagograms when the typical signs and symptoms of vomiting, chest pain, and subcutaneous emphysema occur. If the clinical features are atypical, CT may be performed early in the clinical course. Thus, recognition of the CT findings of esophageal perforation is important. MATERIALS AND METHODS: We reviewed the CT scans of 12 patients with esophageal perforation. The site of perforation was the cervical esophagus in three and the thoracic esophagus in nine. The causes of the perforations were neoplastic (four patients), idiopathic (three patients), iatrogenic (three patients), and traumatic (two patients). RESULTS: CT abnormalities included esophageal thickening in nine patients, periesophageal fluid in 11 patients, extraluminal air in 11, and pleural effusion in nine. The site of the perforation was visible on the CT scan in two patients. In four patients (33%), CT findings were the first indication of esophageal perforation. CONCLUSION: For patients who have atypical signs and symptoms, CT scans optimally define the extraluminal manifestations of esophageal perforation. Extraesophageal air is the most useful finding. The CT findings may be the first indication of the diagnosis.

Adolescent↗