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[Analysis of energy intake, macronutrients and micronutrients in a child population].

With the objective to know precisely the qualitative and quantitative food intake of the infant population of a Health Care Area, the weekly intake of Energy, Proteins, Total and Saturated Fat, Food Fiber, Cholesterol, Calcium, Phosphorus, Magnesium. Iron, Zinc and Vitamin A is studied in 187 pupils, representative of the whole (835 children) population of two schools of Fuenlabrada and Leganés (Madrid), following the Weekly Register technique. Total consumption is quantified, and stratified according to sex and age groups. In order to perform a proper evaluation of these parameters, their adequacy to the Intake Recommendations for age and sex is analyzed, finding an excessive intake of calories, proteins and lipids in all age groups: being saturated Fat a third of the total daily Fat; Carbohydrates intake less than 50% of total energy, which would be desirable to maintain the nutritional ratio. Calcium intake, insufficient in some age group, together with the strong correlation proteins-phosphorus as well as total and saturated Fat with Cholesterol of the diet, allow to conclude that the excessive protein intake is predominantly due to meat products. It is also noted the lower intake of Zinc, Calcium, Magnesium, as to the recommended in certain age groups, therefore said individuals are at risk to suffer deficit of these micronutrients.

Adolescent

Safe protein-calorie ratios in diets. The relative importance of protein and energy intake as causal factors in malnutrition.

There has been up to now a lack of agreement as to the way in which protein and energy requirements could be combined to give estimates of adequate dietary protein-energy ratios. In particular, the relevance of the simple ratio, average protein--average energy requirement as a basis for assessing diets, has been questioned on the grounds that it fails to take account of individual variability in needs for energy, and of the extent to which these may be independent of variability in protein requirements. The main problem is to evaluate the range over which individuals can adapt either energy intake to suit expenditure, or expenditure to suit intake, without detriment to health or growth. One solution adopted by Beaton and Swiss in a recent paper is to accept the range of observed variability of energy intakes in normal populations as a measure of this. An alterative is to make use of experimental evidence for the minimum energy intake for maintenance of body energy content. These two approaches are compared, and are shown to give quantitatively similar results. The method based on minimum maintenance requirements offers the further advantage that it allows an assessment of dietary situations in relation to the likelihood of occurrence of different forms of protein--energy malnutrition; those situations in which protein deficiency is a secondary consequence of low energy intake are differentiated from those in which the primary cause is an inadequate level of protein in the diet. The adequate "safe" level of protein-energy ratio in the diets of 2- to 3-year old children is close to 5% and since most varieties of cereal grains appear to provide utilizable protein levels of close to this amount, this lends further support to the view that primary protein deficiency is unlikely to be the main factor causing protein-energy malnutrition in communities for which cereals are the cheapest source of energy.

Breast Feeding

Effects of live weight and energy intake on nitrogen balance and total N requirement of lambs.

1. Results of 298 nitrogen balance studies from experiments with male cross-bred lambs, ranging in weight from 3 to 38 kg, which had been either fasted, or fed entirely on liqid diets of varying protein content at various energy intakes up to ad lib. intake, were used to quantitatively describe the effects of the amount and quality of absorbed protein, energy intake and live weight on N balance and total N requirement of lambs. 2. When N intake was less than the amount required, N balance was independent of energy intake, but linearly related to absorbed N and metabolic body-weight (live weight-O-75). In the fitted relationship, the coefficient of absorbed N was shown to be an estimate of the biological value of absorbed protein and the coefficient of metabolic body-weight was an estimate of the loss of endogenous N in both urine and faeces. For the milk-based diets used in the experiment biological value was 0-72 and the total endogenous N loss in urine and faeces was 148 mg N/kg per d. 3. When N intake was in excess of the amount required, N balance in lambs of a constant live weight increased linearly with metabolizable energy (ME) intake, at a rate that decreased with increasing live weight. Similarly at constant ME intake, N balance was a curvilinear decreasing function of metabolic body-weight, it was constant for lambs of all weights when ME intake was about 0-23 MJ/kg-0-75 per d, but it decreased linearly with increasing metabolic body-weight for ME intakes above this level. 4. N balance of fasted lambs was several times less than predicted by either of the relationships established for fed animals, and was found to be linearly related to metabolic body-weight. 5. The effects of energy intake and live weight on the total N requirement of lambs were determined. When total N requirement was expressed per unit of energy intake, it was found to be constant at 0-9 g N/MJ ME for all lambs irrespective of live weight when ME intake was 0-23 MJ/kg-0-75 per d. However, as ME intake/unit metabolic body-weight was raised above this level, N requirement/unit ME intake increased for lambs weighing less than c. 23 kg, but decreased for heavier animals.

Animal Nutritional Physiological Phenomena

The quantitative effects of maternal dietary energy intake on pregnancy and lactation in rural Gambian women.

The quantitative relationships between dietary energy intake and weight gain in pregnancy, birthweight and lactation performance during the first three months of infancy have been studied in such a way as to take account of major differences in the patterns of heavy manual labour at different times of the year in a subsistence farming community. Maternal weight gain and the accumulation of subcutaneous fat were significantly lower when the last trimester of pregnancy fell during the time of heaviest farm work and lowest energy intakes. The birth-weight of babies was also significantly correlated with differences in energy intake throughout the year. During early lactation breast milk yields were significantly related to concomitant alterations in the subcutaneous fat stores. Evidence has been produced which suggests that in undernourished nursing women there could be a competition for dietary energy between the repleting maternal subcutaneous fat organs and the mammary glands at the expense of milk production.

Adolescent

The effects of varying protein and energy intakes on the growth and body composition of pigs. 2. The effects of varying both energy and protein intake.

The objective of the experiment was to define the form of the relationship between varying levels of protein and energy intake and the performance of young pigs. Forty-four young-pigs were assigned at 12 kg live weight for 6 weeks either to an initial slaughter group (n 8) or to one of the nine feeding treatments (n 4); three allowances of a high-protein food with 355 g crude protein (nitrogen x 6.25; CP)/kg (P1, P2, P3) at three levels of feeding (L, M and H). Each feeding level was met by supplementing the allowance of feed P with the appropriate amount of starch and each treatment had two males and two females. The rate of protein deposition was not affected by feeding level at the two lowest allowances of basal feed P (P1 and P2), but it increased with increasing the feeding level for the pigs on treatment P3. Males deposited more protein than females, but this effect was more pronounced with treatment P3. The rate of lipid deposition increased with each increase in the level of feeding and decreased with increasing the allowance of feed P. The calculated efficiency of protein utilization (ep) was expressed as a function of the energy:protein ratio in the feed (MJ metabolizable energy/kg digestible CP). The best model to describe the relationship was a linear-plateau model, with the maximum value for ep of 0.814 at 73 MJ/kg. This relationship provided the basis of a model that could predict the response of a growing pig to its diet as rates of protein and lipid retention.

Animals

Energy intake, disability, disease and skinfold thickness in a long-stay hospital.

Body build was assessed by measuring supinator and triceps skinfold thickness of 66 elderly patients in a long-stay hospital. Nursing staff made seven day records of the food intakes for the subjects. These were used to estimate calorie intakes. There was no relationship between energy intake and skinfold thickness. Reduced skinfold thicknesses were more common in subjects with rheumatoid arthritis or a previous fractured neck of femur than in those with cerebro-vascular disease or any other disorder. The findings suggest that the body build of long-stay patients is usually determined by their energy intake prior to admission. The feeding patterns of patients, once they are admitted, have little effect on body build.

Aged

Influence of caloric density on energy intake by dairy cows.

Twenty-four Holstein cows were fed mixed diets of alfalfa hay and concentrate in a series of periods to determine the relationship between caloric density (mcal digestible energy/liter) of the diet and energy intake. Five diets with caloric densities of .58, .63, .68, .84, and 1.17 (as-fed form) were used. Steers were fed the diets in digestion trials to determine maintenance digestibility. Intake of digestible energy was adjusted for intake. Means of digestible energy intakes (kcal/day per kg. 75) were: 291.7, 324.0, 370.0, 371.4, and 369.1 for diets with caloric densities of .58, .63, .68, .68, .84, and 1.17. Physical fill was limiting for the two most dilute diets. The diet with caloric density of .68 represented the point above which physiological regulation was employed by the animals. The relationship between digestible energy intake (kcal/day per kg-75) body weight (Y) and caloric density (mcal/liter dry matter, as fed form) (X) was Y = 759.2X-148.4, simple correlation .99, for diets with caloric densities of .58, .63, and .68. Potential uses of this relationship in maximizing forage utilization and formulating diets to meet specific energy requirements are cited.

Animal Feed

Relationships between blood pressure and measures of dietary energy intake, physical fitness, and physical activity in Australian children aged 11-12 years.

STUDY OBJECTIVE: The aim was to examine associations between blood pressure and dietary energy intake, physical activity, and physical fitness in Australian children. DESIGN: The study was a survey of year 7 children attending schools in metropolitan Perth. SETTING: Survey schools were located in suburbs representative of the range of socioeconomic strata in metropolitan Perth. PARTICIPANTS: Data were obtained on 1311 out of 2045 eligible children (64%). The sample included 681 boys and 630 girls. Mean age was 12.0 (SD 0.4) years. MEASUREMENTS AND MAIN RESULTS: Triplicate blood pressure measurements were obtained using a Dinamap oscillometric recorder. Dietary energy intakes were computed from two week day 24 h records. Physical activity was assessed using questionnaires. Physical fitness was measured using a shuttle run test. Additional measurements included weight, height, and skinfold thickness at four sites. A previous observation of an inverse relationship between diastolic blood pressure and dietary energy intake in boys was confirmed. There was evidence of an inverse relationship in girls but not in boys between blood pressure and physical activity. There was little evidence of relationships between blood pressure and physical fitness. CONCLUSIONS: Compared with weight and body mass index, dietary energy intake and the chosen measures of physical activity and physical fitness are poor predictors of blood pressure in the population studied.

Blood Pressure

Across-the-day monitoring of mood and energy intake before, during, and after a very-low-calorie diet.

Mood, hunger, and energy intake were monitored in eight obese women before, during, and after 2 wk on a very-low-calorie diet (VLCD). Energy intake was significantly lower by approximately 30% in the week after the VLCD compared with the prediet week, both from food diaries and at a controlled ad libitum test meal. There was a gradual reduction in hunger, irritability, and urge to eat after 1 wk on the VLCD, which persisted through the postdiet week. Hunger and discontent were greatest in the evening during the first few days of the VLCD but diminished as the duration of the VLCD increased.

Affect

Human protein requirements: the effect of variations in energy intake within the maintenance range.

Protein requirement studies in man generally avoid deficient dietary energy intakes because they decrease the efficiency of nitrogen utilization, but the opposite effect of excess dietary energy is usually overlooked. Four young men were fed the 1973 FAO/WHO safe level of egg protein (0.57 g/kg) at several levels of dietary energy. The data indicate that a significant proportion of the population may require excess energy intakes to maintain nitrogen balance at this level of dietary protein. Variations in dietary energy ranging from submaintenance to 15 to 20% above estimated maintenance needs altered net egg protein utilization in three subjects by 2 to 4.5 units/kcal per kg body wt.

Adult

[Insulin-like growth factor I (somatomedin C) in premature infants on total parenteral nutrition. Relations with nutritional status and protein-energy intakes].

Insulin-like growth factor I (IGF I) is like prealbumin and transferrin a marker of nutritional status. Its level increases with gestational age. The levels of IGF I (96 times), transferrin (86 times) and prealbumin (69 times) were measured in blood samples from 26 premature infants aged 8 to 78 days (gestational age: 28 to 34 weeks, birth weight: 840 to 1,800 g). At the time of sampling, all the infants were on total parenteral nutrition (360 +/- 42 kJ/kg/day and 2.5 +/- 0.3 g of proteins/kg/day). The results were analysed with reference to anthropometric parameters (weight, height, head circumference, skinfolds and arm circumference). There was no correlation between plasma IGF I and anthropometric measurements. There were significant correlations between IGF I and transferrin (p less than 0.01), prealbumin (p less than 0.05), protein intake (p less than 0.01) an energy intake (p less than 0.05). Plasma IGF I increased at the end of the first week of parenteral nutrition in all the 5 infants having initial low values. The plasma IGF I was not correlated with the duration of parenteral nutrition in the 26 infants after the second week of nutrition. IGF I measurement is useful for evaluating the protein nutritional status of premature infants on total parenteral nutrition.

Energy Intake

Feeding problems in children with congenital heart disease: the impact on energy intake and growth outcome.

Cross-sectional data on growth outcome, upper-arm measurements and energy intake have been analysed according to the presence or absence of early feeding problems and poor appetite in 40 children (0.9-13 years) with congenital heart disease (CHD). At the time of study, refusal to eat or poor appetite was reported as a significant problem in 19 children and subnormal height and/or weight were recorded in 11 children. The children ate considerably less calories than recommended for healthy children. The cross-sectional analyses showed that children with poor appetite had significantly (P less than 0.05 and P less than 0.01) lower outcome values of growth and upper-arm measurements than their disabled counterparts with no feeding problems and good appetite. Children with feeding problems also tended to eat less than children without feeding problems. For most parents (65%) feeding of infants and children with CHD involves difficulties, time and anxiety. This study has shown that the parents' experience about feeding problems may be a good predictor for low growth outcome and low voluntary food intake of the child. Whenever feeding problems are reported, nutritional intervention should be offered in order to increase the caloric intake of the child and to develop a sound feeding relationship in the family.

Adolescent

Validation of estimates of energy intake by weighed dietary record and diet history in children and adolescents.

Energy intakes assessed by 7-d weighted dietary records (EI-WDRs) and diet histories (EI-DHs) were compared with concurrent estimates of total energy expenditure (TEE) by the doubly labeled water method in 78 subjects aged 3-18 y. EI-WDRs were not obtained from the 3- and 5-y-old subjects. EI-WDRs in the 7- and 9-y-old children were 108 +/- 25% (n = 12) and 97 +/- 15% (n = 12), respectively, of corresponding TEE values showing good agreement. However in the 12-, 15-, and 18-y-old subjects EI-WDR averaged 89 +/- 12% (n = 12), 78 +/- 18% (n = 12), and 73 +/- 25% (n = 10), respectively, of corresponding TEE values. The difference was greater than or equal to 20% in 13 adolescents. Mean EI-DHs were 114 +/- 19% (3 y), 111 +/- 19% (5 y), 111 +/- 23% (7 y), 106 +/- 9% (9 y), 114 +/- 17% (12 y), 101 +/- 21% (15 y), and 98 +/- 21% (18 y) of TEE estimates. Differences were significant in the 3-, 9-, and 12-y-old subjects. Results suggest that 7-d EI-WDRs tend to underestimate food intake of adolescents. Although EI-DHs were biased towards overestimation in most age groups and individual measurements lacked precision, EI-DHs were more representative of habitual intake than were EI-WDRs.

Adolescent

Variation in energy intake of aldolescent schoolgirls.

Twenty-four 16 to 17 year-old grammar school girls completed daily dietary histories (for eight weeks), and recorded details of mood, appetite and menstrual cycle. Marked daily variation in energy intakes was noted: on average an individual's highest daily intake was nearly four times her lowest intake, one subject having a nearly tenfold difference. Fluctuations were not related to mood, suggesting that this has less influence on dietary patterns than is generally supposed. While sitting examinations, energy intake was reduced by an average of 11.85%. It was not significantly changed during a field trip or by menstruation. This study suggests that dietary patterns previously considered to be abnormal or unusual are exhibited by and firmly entrenched in normal school girls.

Adolescent

The influence of dietary protein concentration and energy intake on mitogen response and tumor growth in melanoma-bearing mice.

The effects of energy deprivation and low or high dietary protein levels upon lymphocyte transformation of spleen cells from syngeneic tumor-bearing and control mice were studied in a murine model of malignant melanoma. Both T- and B-lymphocyte transformation were significantly stimulated by the presence of a growing melanoma. T-cell responses however, were dependent only upon dietary protein concentrations, not the level of energy intake; whereas, the converse was true for B cells. Moreover, mice fed stock diet had the lowest response to mitogens of all diets tested. Except for mice receiving a 15% casein diet, tumor weights were generally not affected by level of intake or the amount of dietary protein. Others have demonstrated that melanoma cells have a greater need for tyrosine or phenylalanine than other tumor cells; thus we hypothesized that lymphocyte transformation may be depressed by relatively low phenylalanine or tyrosine levels in the diet when protein intakes are limited by either a low dietary concentration a restricted intake of a diet containing adequate protein, or both.

Animals

[Performance dependent lysine requirement of fattening pigs. 3. Effect of amino acid and energy intake on fat, protein and lysine deposition of swine].

The gain in structural matter had a linear course with a corresponding feeding intensity and depending on the period of fattening. However, the animals given high-energy diets deposited 130 g protein per day during the first fattening period, this deposition being compensated in the course of further growth by a considerably lower deposition in the sense of aequifinality. Up to a live weight of 70 kg, animals subjected first to restricted feeding and then to fully balanced feeding revealed the highest protein deposition during the last period of fattening, this fact emphasizing the leanmeat character of the animal material used. The daily fat deposition was found clearly determined by energy intake and independent of amino acid supply. Lysine conversion was influenced by the intake of lysine and energy. Under feeding to norm it reached some 40 and 30% during the first and second periods of fattening, respectively.

Adipose Tissue

Model for predicting egg output and metabolisable energy intake of laying pullets.

1. The data compiled by Marsden and Morris (1987) to examine the relationships between environmental temperature and the long-term, adapted responses of laying pullets were divided at random into two subsets of 99 and 113 observations. The first subset was used to estimate regression coefficients for an econometric model, and the second subset to validate the model. 2. Equations to predict inputs (costs) and outputs (returns) were estimated with a three-stage least-squares regression model. Three stage least-squares estimation is a technique which corrects for the simultaneity of variables within the model and correlation across equations of the model. This results in more efficient estimates of the regression coefficients. 3. The final output and output equations were: MEI = 253.86-190.31EM+5.766EM2-0.546EM3 + 0.7034T-0.004388T3 + 695.08BW-120.23BW2 + 397.37ME-13.132ME2-1.06MEXT; R2 = 0.86; EO = 119 + 0.025MEI -0.0000045MEI2-1.462T-0.0791T2-135.3BW + 38.31BW2-1.483T X BW + 0.0288T2 X BW + 0.673 delta BW; R2 = 0.59 where MEI = daily metabolisable energy intake (kJ/bird d), T = environmental temperature (degree C), EO = egg output (g/bird d), BW = body weight, and ME = metabolisable energy concentration (kJ/g). The values for R2 indicate very good fits considering that the data were recorded over a 26-year period in 14 different laboratories. 4. This statistical model can serve as the basis for an econometric model of egg production to determine the environmental temperature that maximises profits from laying pullets of different body weights.

Animals