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Results for “Epilepsy, Post-Traumatic”

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At least 37 records · Page 2Linked to original sources
PubMed1978

Posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.

A patient with uncontrolled posttraumatic epilepsy and acute intermittent prophyria was subjected to successive therapeutic trials with phenytoin, carbamazepine, and clonazepam, while eating an adequate diet. Both phenytoin and carbamazepine treatments caused significant increases in porphobilinogen excretion and appeared to induce acute porphyric attacks. In contrast, treatment with clonazepam under rigid dietary control for 10 days caused no increase in porphilbinogen excretion. During the subsequent 7 months of treatment with clonazepam, neither seizures nor porphyric attacks recurred. These findings suggest that clonazepam may be a safe and effective treatment for chronic or severe generalized seizure disorders in patients with acute intermittent porphyria.

Acute Disease↗
PubMed1979

Prophylactic phenytoin in severe head injuries.

We are reporting a retrospective study of 62 patients whose head injury was sufficiently severe to cause a high probability of posttraumatic epilepsy. Of 50 patients treated with phenytoin, 10% developed epilepsy of late onset. Twelve patients not treated with phenytoin but who had head injuries of equal magnitude had a 50% incidence of epilepsy. These data from a highly selected group of patients with severe head injuries confirm the bias that treatment with phenytoin decreases the incidence of posttraumatic epilepsy.

Adult↗
PubMed1979

[The expanding skull fracture (author's transl)].

An expanding skull fracture with exceptional extension into the frontal sinus, the orbit and the ethmoidal cells is discussed. A 12 year old boy fell down the stairs at the age of 8 years and fractured his left frontal bone with extension to the base of the skull. He was seen because of a swelling of the scalp, an intermittent orbital oedema and convulsions. At neurosurgery a large gaping fracture of the frontal bone was found and this was interposed with fibrous tissue and relatively denatured cerebral tissue. The management both neurosurgical and rhinological is discussed.

Child↗
PubMed1979

[EEG follow-up studies following posttraumatic apallic syndrome in children].

Seventeen children, who had sustained craniocerebral traumata with posttraumatic apallic syndromes, were examined electroencephalographically for an average period of six years. Until incipient clinical remission of the apallic syndrome, the electroencephalographic results correlated essentially with the clinical picture; later on, there was observed only a relatively loose correlation between the electroencephalogram and the neurological or psychic condition. Despite serious and irreversible brain damage, complete normalization of the electroencephalogram could be observed in individual cases.

Adolescent↗
PubMed1979

The significance of combined risk factors for the incidence of posttraumatic early fits and epilepsy.

After a brief outline of autonomic incidence of posttraumatic early fits as compared to "real" posttraumatic epilepsy, such traumatologic and neurologic factors are compared that lead much more frequently to early fits. Furthermore, the conditions of early fits and their relation to the occurrence of chronic posttraumatic epilepsy are investigated. Statistically and prognostically reliable data are only found when combined groups of high risk factors of different valence rather than individual data are considered. Such a statistically proved combination is the connection of intracranial hematomas, posttraumatic amnesia of more than 3 hours, neurologic dysfunctions and a persisting organic psychosyndrome.

Adult↗
PubMedDate not supplied

Long-term prognosis of early epilepsy in juvenile head-injured patients (preliminary results).

The authors present the results of a long-term follow up of 52 juvenile head-injured patients who showed early epileptic seizures. The purpose of this study is to stress the role of long-term prognosis in the early seizures and to determine in which cases a treatment preventing late seizures is eligible. They consider long-term prognosis as to be favourable. Late epilepsy occurred in 15.3% of the cases and responded favourably to anticonvulsive therapy. They suggest prophylaptic treatment in those patients who had loss of consciousness immediately after trauma, recurring seizures, coma and/or surgery.

Adolescent↗
PubMedDate not supplied

Early post traumatic seizures in adults. Study of 84 cases.

In a series of 2.980 brain-injured patients, 84 (2.8%) showed epileptic seizures. Epilepsy occurred with a higher incidence rate in operated patients (11.6%) than in non operated ones (1.2%). Seizures appeared within the first week since trauma in 91% of the cases. They have been single in 48%, recurring in 34%, with figures of status epilepticus in 16% partial in 61%, and GM in 33%. Prognosis quoad vitam of early epilepsy seems to be favourable, however, in severely brain-injured patients, seizures occur more frequently and may determine a worsening of the clinical picture even if they are not responsible for the death.

Adolescent↗