[Recurrence of epiphyseal slipping following Imhäuser's osteotomy in childhood].
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In a retrospective review of 43 femoral fractures, three dogs had separation of the femoral capital epiphysis from the metaphysis in the absence of trauma. Two of these dogs also had evidence of pathology in the contralateral femoral neck including, in one dog, displacement of the capital epiphysis in relation to the metaphysis without actual separation. The case histories, radiographic features and histopathological findings of these cases were reviewed and compared with previous cases of slipped capital femoral epiphysis (SCFE) reported in dogs and also with SCFE in children. Pre-slip, acute, chronic and acute-on-chronic slips were Identified. Based on the cases reviewed, the authors advise internal fixation of stable slipped epiphyses in dogs. This may also be appropriate for unstable separations, although resorption of the femoral neck may preclude stable fixation and necessitate femoral head and neck excision.
The aim of this study was to ascertain the frequency of adverse events occuring during GH therapy in Australia and New Zealand since 1988. Data for children receiving GH has been collected prospectively on a national database, OZGROW, after informed consent has been given. Adverse events were coded by clinicians and have been analysed in relation to the nature of the event and the underlying diagnosis. There were 2922 subjects analysed, representing 9004 years of GH therapy. 151 subjects reported a total of 210 adverse events giving an overall frequency of 2.3% adverse events/patient treated year. Events that were probably related to GH therapy included peripheral oedema, injection site problems and increased frequency of kyphoscoliosis and slipped epiphysis in some groups. Adverse events were more frequent in growth hormone deficient children who had previously been treated for leukaemia, 8.1%, and in children previously treated for craniopharyngioma, 5.6%. A lower frequency was found for those with a diagnosis of idiopathic short stature, 1.6%, and familial short stature, 0.9%. Kyphoscoliosis was more frequently seen in Turner's syndrome, and slipped epiphyses in adolescent individuals with growth hormone deficiency, especially following treatment for leukaemia. There were no de novo tumours reported but the frequencies of recurrence/patient year for leukaemia, solid cranial tumours and craniopharyngioma were 1.1%, 2.2% and 3.8% respectively. A low frequency of adverse events has been reported on the OZGROW database but subsets of patients may be at increased risk of musculoskeletal abnormalities during GH therapy. The frequency of tumour recurrence during therapy is not different from known rates of recurrence in individuals not treated with GH.
Two boys aged 5 and 9 treated because of congenital, hereditary anhidrotic ectodermal osteo-chondrodystrophy have been presented. Slipped epiphyses were found among other coexisting articular disturbances.
From 1978 through 1988, 27 severe slipped epiphyses (Grade III) in 23 adolescent patients were treated with a cuneiform osteotomy of the proximal neck of the femur. Average time of followup was 8 years 5 months. The results were graded by the criteria of Southwick, with emphasis on pain, function, range of motion, and radiographic appearance. Arbitrarily, no hips were rated excellent, because the authors thought that this rating should be reserved for normal hips that have not had any disease process nor surgical procedure. There were 19 good, 4 fair, and 4 poor results. The 4 poor results were in patients with avascular necrosis. The avascular necrosis rate was 15%. Eight hips had some joint space narrowing during the postoperative followup period. All joint space narrowing was resolved by 20 months postoperatively. All patients, including those with avascular necrosis, improved in joint flexion and joint internal rotation. Although the avascular necrosis rate of 15% is significant, the authors believe that the potential for restoring hip anatomy and providing a normally functioning hip in the adolescent patient makes this procedure a viable treatment option.
Indications and results of 324 grafted or nailed slipped epiphyses, 45 Imhäuser operations and 7 Wiberg osteotomies are analyzed. Fixation in situ gave relatively good long-term results in spite of major displacement. Indication for correction should be based less on pre-arthrotic deformity than on clinical considerations. Deformity does not always correspond to development of arthrosis, but is determined in parts by dystrophy of cartilage. Results of Imhäuser's osteotomy are assessed mainly in terms of joint-function, their indications follow his guidelines. Prophylactic nailing and open reduction are discussed.
The authors describe the Dunn's technique that they have followed in 19 cases of severely displaces slipped upper femoral epiphysis. The approach was posterior, subperiosteal for preserving vascularity. The results were good in 15 cases, poor in 4 cases. The indications are detailed.
Pelvis radiographs of 30 children with slipped capital femoral epiphyses (SCFE) were reviewed by four readers to determine the skeletal age. The average chronologic age for girls was 12.1 +/- 1.0 years and that for boys was 14.4 +/- 1.3 years; the average pelvic bone age was 13.2 +/- 0.6 for girls and 15.1 +/- 0.6 years for boys. The chronologic age range was 98 months, and skeletal age range was only 50 months. Pelvis bone age was advanced in the youngest children, normal in most children, and mildly delayed in older children. We conclude that there is a uniform skeletal age or "narrow window" during which epiphyseal slipping occurs, regardless of the child's chronologic age.
We conducted a retrospective study of 97 cases of slipped capital femoral epiphysis occurring in 77 children. Gradual epiphyseal slip frequently occurred, and complications were more frequent with greater degrees of slips. Diagnostic delay should, therefore, be avoided, and a high index of suspicion is necessary when adolescents with leg pain or limp are examined. Minor epiphyseal slip should be carefully fixed in situ, and we suggest that the remainder undergo a gentle manipulation. Only those hips with a persisting deformity need undergo femoral osteotomy.
Proximal femoral varus and derotation osteotomy is a common procedure performed in the management of developmental dysplasia of the hip. This procedure imposes high shear stress on the femoral epiphysis, depending on the degree of varus obtained. We report two cases of proximal femoral epiphyseal slip after varus derotation osteotomy and discuss the management and outcome. Such epiphyseal slip may or may not be symptomatic, and a careful radiologic examination should be carried out in suspected cases. Management should be individualised. Surgical correction of varus may be required.
Complete separation of an epiphysis is a rare complication of neonatal osteomyelitis and septic arthritis. We report two cases of pathologic epiphyseal separation after neonatal osteomyelitis, involving the distal and proximal femoral epiphyses with a follow-up of 2 and 7.5 years, respectively. Birth trauma, scurvy, and nonaccidental injury should be considered in the differential diagnosis of pathologic epiphyseal slip. The pitfalls in diagnosis are many, and plain radiograms of unossified epiphyses are often misleading. A high index of suspicion and the use of imaging modalities are useful in making an early diagnosis of epiphyseal slip. The optimal treatment is controversial, and the long-term prognosis is uncertain. The potential for recovery appears to be excellent, provided an early diagnosis is made and prompt treatment by anatomic reduction of the displaced epiphysis is instituted.
Results of treatment for slipped capital epiphysis with one-time head-neck transfiction and subtrochanteric corrective osteotomy in 21 patients (21 hips) operated at Institute of Orthopaedics and Rehabilitation in Poznań between 1973 and 1991 have been presented. Indication for this type of operation was acute-on-chronic slip and magnitude of epiphyseal slip not less than 1/3 of neck width. The follow-up ranged from 4 to 21 years (mean 11y). Using Hall and Southwick criteria modified by Szypryt results in 7 cases were rated excellent, good in 10, fair in 1 and poor in 3 cases. Radiologically 3 cases were excellent, 6 were good, 7 fair and 5 cases were rated poor. Aseptic necrosis of the femoral head occurred in 1 case, chondrolysis in 2 and superficial infection in 1 case. The method proved to be safe in treatment for slipped capital femoral epiphysis.
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