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Canine glomerulonephritis: prevalence in dogs submitted at random for euthanasia.

The kidneys from 71 stray dogs submitted for euthanasia were examined by fluorescence microscopy (IF) for evidence of immunecomplex glomerulonephritis (GN) and by histology for evidence of renal pathology. Dogs were divided into three groups according to estimated age: less than one year old (A), adult (B) and aged (C). IgG deposits were found in 0/31 dogs in group A, 6/20 in group B and 10/20 in group C. Diffuse proliferative GN was evident in 0/31, 5/19 and 7/15 dogs in group A, B and C respectively. One dog in group B and two in group C had histological signs of membranous nephropathy. No definite correlation between results of IF and clinical findings were noted and in the aged group the correlation between results of IF and histopathology was poor. These results serve to show that GN may be more common in dogs than previously recognized and that pathological changes may be always accompanied by clinical nephritis.

Animals

Suicide by intravenous injection of a veterinary euthanasia agent: report of a case and toxicologic studies.

Previously reported cases of suicide by intravenous barbiturates, as well as two other unusual cases [5,6], are compared in Table 2. All decedents were either medical or paramedical personnel and familiar with the drugs and the routes of administration used for their suicides. Lethal is used in veterinary euthanasia at an intravenous dose of 1 ml per 5 kg (10 lbs) body weight. Unconsciousness usually occurs during injection and death supervenes within a matter of seconds. The decedent in the present case weighed 90 kg (200 lbs) and had injected at least 40 ml of the drug, approximately twice the recommended lethal dose. There appears to be little doubt of the victim's suicidal intent, since he had used Lethal in his daily occupational duties. Additionally, the physical configuration of the supports devised to hold the syringe was quite stable, and injection stopped only when the decedent's hand came to rest upon the towels. To our knowledge, the present case represents the only one of its kind in the literature.

1-Propanol

Euthanasia.

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Ethics, Medical