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At least 37 records · Page 2Linked to original sources
PubMed1992

Microvascular anastomosis of a rectus abdominis free flap into a prosthetic vascular bypass graft.

Distal bypass grafts are frequently employed to revascularize lower extremities and to replace major peripheral vessels following excision of large soft-tissue or bone tumors. Autogenous vein grafts are generally used for such bypasses, when available. Large wounds associated with peripheral vascular disease or excision of massive tumors frequently require concomitant free-tissue transfers. Anastomosis of a free-tissue transfer pedicle to a vein bypass graft has been reported. The first successful case of an anastomosis of a flap pedicle to a Gore-tex bypass graft is presented.

Abdominal Muscles↗
PubMed1983

Femoral pain of solitary neurofibromatous origin: a report of three cases.

Three patients, each with a solitary neurofibroma in the thigh, are described. The presenting complaint in each case was pain. A neurofibroma of a branch of the femoral nerve was found in two cases and an intraosseous neurofibroma of the femoral shaft was present in the third. An excellent recovery was observed in each of these three patients following surgical excision of the tumour. Attention is drawn to the unduly long interval between the onset of painful symptoms and the achievement of a clinical diagnosis leading to a surgical cure in each instance.

Adult↗
PubMed1986

Characteristics of a cell line established from a patient with multiple osteosarcoma, appearing 13 years after treatment for bilateral retinoblastoma.

An osteosarcoma cell line, OHS, was established from a patient with multiple skeletal manifestations of osteosarcoma, developing after bilateral retinoblastoma. The tumor cells expressed sarcoma-associated antigens and showed rapid growth in monolayers and as multicellular spheroids. They formed distinct colonies in soft agar, and subcutaneous tumors in nude mice. Morphological studies indicated that OHS cells had retained important characteristics of the cells of origin. No deletion of the retinoblastoma genes on chromosome 13q14 could be demonstrated with the banding techniques used. However, cytogenetic studies revealed double minute chromosomes, as evidence of gene amplification, as well as translocations involving chromosomes 1,6,11 and 13. The OHS line can be used to study the genetic basis of tumor initiation and growth, and to elucidate factors predisposing for second primary cancers in retinoblastoma patients.

Adolescent↗
PubMed1979

Lymph node metastases from osteoblastic osteogenic sarcoma visible on plain films.

The radiologic features of lymph node metastases from osteogenic sarcoma visible on plain films in two patients are described. In one patient the lymph node ossification was visible on presentation and in the other patient it was demonstrated six months after the initial diagnosis. The radiologic pattern in both cases was similar. Deposition of metastatic osteoid tissue in lymph nodes, to such a degree that it can be recognized on plain films, appears to be a distinctly uncommon complication of this malignant neoplasm. It is considered probable that this complication occurs with the osteoblastic type of osteogenic sarcoma. It is suggested that lymphography might be of value in the detection of such metastases at an earlier stage, thus influencing the plan of treatment.

Adolescent↗
PubMed1984

The submicroscopic structure of a chondroblastic osteogenic sarcoma.

Two patients are reported with a chondroid form of osteosarcoma, whose structure was also analyzed submicroscopically. The clinical and radiologic picture and the rapid lethal progress of the disease indicated an osteosarcoma, while both histologic and electron-microscopic investigation suggested the prevalence of malignant chondroid. Progress in the treatment of osteosarcoma makes it essential for diagnostic, therapeutic and prognostic reasons to reintroduce subclassification of these tumors in an attempt to correlate their morphological picture with their biologic properties. According to our experience to date, it seems that the cartilaginous component in no way ameliorates the rapid malignant penetration of the osteosarcoma. It is essential to distinguish these tumors from the usually much less malignant chondrosarcomas and to place the chondroblastic osteogenic sarcoma among in spite of the clear predominance of the malignant chondroid, and thus also introduce highly radical and combined therapy.

Adolescent↗
PubMed1995

Extracranial metastases of meningioma.

We report two unusual cases of intracranial meningioma with extracranial metastases to bone. The diagnosis was made by fine needle aspiration biopsy in both cases and confirmed by open biopsy in one. The lungs were spared in both. A review of the literature is included.

Adult↗