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At least 37 records · Page 2Linked to original sources
PubMed1976

Studies to improve fixation of human nerves. IV. Effect of time elapsed between death and glutaraldehyde fixation on density of microtubules and neurofilaments.

Glutaraldehyde fixation of rat peroneal nerves after the animal was killed (simulated autopsy) was associated with a statistically significant decrease of density (number per unit area) of microtubules (MT) in comparison with controls (simulated biopsy). The density of MT decreased progressively with prolongation of time elapsed prior to glutaraldehyde fixation (1, 6, and 12 hours). Such a time effect was not demonstrated for density of neurofilaments.

Animals↗
PubMed1976

[High tibial osteotomy--fixation by means of external fixation--indication, technique, complications (author's transl)].

High tibial osteotomy has proved its value in the treatment of gonarthrosis with or without axis deformity. The thrust of weight-bearing and other stresses is lessened on the degenerated tibial condyle and transferred to the more normal condyle. The stable fixation by means of external fixation allows early movement of the knee joint.-R-ferences to operative technique, indication, complications and after-treatment.

Arthrodesis↗
PubMed1979

[Fixation of the osteotomised greater trochanter by total hip prosthesis in 181 cases. Advantages of the fixation with intramedullary Kirschner wire and the figure-of-eight wire loop (author's transl)].

It is mostly possible to implant a total hip prosthesis without an osteotomy of the greater trochanter. It is however necessary to do it in some cases such as an ankylosed hip, a reimplantation and a severe form of the coxarthrosis. 181 patients have been followed up. The fixation by intramedullary Kirschner wire and figure-of-eight wire loop has been of success. It is a simple method. No fracture of the greater trochanter has been observed.

Aged↗
PubMed1978

Fixation of pelvic fractures and dislocations. An experimental study on the loading of pelvic fractures and sacro-iliac dislocations after external compression fixation.

A trapezoid external compression fixation frame, assembled with the Hoffman instruments, was used for stabilizing experimental injuries to the pelvic skeleton of ten cadaver specimens. The resistance to loading in a position corresponding to upright standing was tested in 17 experiments and related to the calculated load in vivo. The results indicated that ipsilateral injuries, either presenting as dislocations of the sacro-iliac joint and symphysis or as unilateral fractures of the sacrum or ilium in combination with fractures of the pubic rami could be stabilized by the external compression frame well enough to permit weight-bearing in the upright standing position. Bilateral injuries to the pelvic skeleton, vertical or oblique, could not, however, be stabilized enough to resist more than a fraction of the normal load in the upright standing position.

Aged↗
PubMed1978

The effect of limited fragmentation of porcine 19 S IgM on agglutination and complement fixation. Evidence that at least two intact subunits are required for complement fixation by IgM antibody.antigen complexes.

Limited fragmentation of pig IgM anti-Salmonella with pepsin gave a 12 S product which agglutinated Salmonella almost as efficiently as the original IgM but the complement fixing ability of the complexes was substantially lowered. The 12 S product was shown to consist of molecular entities having intact Fc regions with an average of 3 or 4 intact Fab arms still attached. Our results appeared to show that removal of Fab arms by pepsin was a random process and on this basis a mathematical model was set up. From this model it was possible to calculate the frequencies of molecular entities which would give rise to the observed average of 3 or 4 Fab arms. The most likely explanation of our results is that complexes need to be formed by molecules having at least two intact subunits before efficient complement fixation takes place.

Animals↗
PubMed1979

The complement fixation test and African trypanosomiasis. II. The complement fixation test as an aid for assessing therapy.

Complement-fixing antibody titres decline after successful treatment of trypanosoma infected cattle during a fixed period. For investigating the practicability of the resulting double test procedure in the field, cattle under controlled drug regimes were tested at treatment and again 3 weeks later. Alternatively, the results from groups of treated and untreated animals from the same area were compared. Both serological and parasitological test results indicated an insuffieicnt effectiveness of therapy in the area under investibation.

Animals↗