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[Light- and electronmicroscopic findings in nine auto-alloplastic vascular grafts (Sparks-Mandril) (author's transl)].

Auto-alloplastic arterial prostheses with a dacron mesh of 1 or 2 layers according to Sparks were investigated by light and electron microscopy after variable times of incorporation and perfusion. At the end of the organization-period the characteristic structure of the wall is composed of three layers. The interior layer is adapted to the form of the mandril, which holds the place of the lumen, the medial layer is formed according to the inforcing dacron-mesh. With increasing duration of incorporation the granulation tissue shows somewhat less inflammatory cells and capillaries and more collagen fibres. There were some characteristic disturbances of healing only partly due to infection, which resulted in focal or total necrosis of the granulation tissue: Not all of these findings were of clinical importance. Already after a perfusion time of 10 months an atherosclerosis of variable degree was found. This atherosclerosis started from mural thrombi and showed in the electron microscope proliferations of modified smooth muscle cells. Advantages and disadvantages of the autoalloplastic arterial prostheses are discussed.

Arterial Occlusive Diseases

Modern trends of surgical treatment in male infertility: alloplastic spermatocele in cases of excretory azoospermia.

It is demonstrated in 30 rats that implantation of a cup-shaped silicone prothesis upon the head and the tail of the epididymis can serve as an alloplastic spermatocele. The implantation of six similar protheses upon the epididymis in bulls confirms the results obtained in rats. Spermatozoa aspirated from this prothesis up to 4 months after operation showed good morphology and motility which improved: (1) the earlier they were obtained after surgery, and (2) the nearer the tail of the epididymis, the prothesis was implanted.

Animals

Healing of periodontal flaps following use of MBR 4197 (flucrylate) in rhesus monkeys. A clinical and histological evaluation.

Experimental periodontal surgery was performed on six adult Rhesus monkeys, using the modified Widman flap technique. Each monkey provided four or six segments for flap surgery, and three different experimental time intervals were used. Flaps were immobilized after surgery by conventional sutures or by application of MBR 4197 cyanoacrylate spray. Each animal provided its own contralateral comparison, and the mode of flap immobilization was reversed in the corresponding segments in the other animal of each experimental group. One monkey died approximately 12 hours after surgery, and the other animals were sacrificed at 14, 35 and 180 days. Histological sections were prepared from all operated areas, and examined for the pattern of healing. A special staining technique was used to determine the presence of MBR 4197 within the tissues.

Alveolar Process

[Experiences with the Sparks-prosthesis in the periphery (author's transl)].

According to our own experiences it is not advisable to implant the Sparks-Mandril in an extremity which gangrene. The ideal case for implantation is the patient with short walking distance and an unsuitable vena saphena magna. The prothesis is useful for the femoro-crural bypass procedure. The thrombogenicity of the Mandril can be neglected by heparinization of the patient or after careful perfusion of the prothesis.

Bacterial Infections

[Histological study of the voluntary traumatic inclusion of a foreign body in the gingival mucosa].

First histological features of traditional tattooing of gingival mucosae using smoke-black are reported. They show the complete tolerance of connective tissue. The microscopic examination occurs several weeks or months after the tattoo was done. Thus, one can notice that carbon particles localize particularly around blood vessels (small arteries), and that never arises inflammatory reaction of any type.

Carbon

[Problem of biological tolerance of vessel prostheses from dacron and synthetic fibre material].

In human beings there have been no observations of heterogenous sarcoma after application of macromolecular artificial implants although such materials have been applied for the last 25 years. Only benign granulomas and inflammatory processes have been described. This paper describes the appearance of double-refraction artificial particles in macrophages and in granulomas encapsulated in the neighborhood of Dacron arterial prosthesis and synthetic suture materials. These processes are possibly an expression of a biological discharge of the implants.

Blood Vessel Prosthesis

[Soft hydrophilic lenses and permanent wear in optical cases. Physio-pathological considerations and conclusions].

The author has noted that the frequency of epithelial lesions appearing during the course of trials with soft hydrophilic lenses containing 40% water diminished almost completely with soft hydrophilic lenses containing 70% water. He attributes these epithelial lesions to anoxia occurring with soft hydrophilic lenses with 40% water. He compares the permeability to oxygen of different types of lenses according to their thickness. He concludes that at present the materials utilised and the thickness of the lenses do not allow permanent wear.

Contact Lenses, Hydrophilic

[Determination of the residual monomer diffusion from implanted kallokryl-K bodies and their mandibular tissue reactions].

The paper, after discussing the problems associated with the implantation of cold-polymerizing polymethyl methacrylates, describes the methods and results of determining the diffusion of residual monomers from implanted Kallokryl K bodies. Also described and discussed are histological studies of the implant supporting tissue and possible consequences of the decreasing, but constant diffusion of residual monomers, respectively.

Acrylates

[Connective tissue of capsules surrounding lavsan under conditions of long-term implantation].

An experimental study of the capsules formed around the net lavsan prostheses at periods of from 7 days to 5.5 years demonstrated that in the process of prolonged implantation morphology and metabolism of the capsule connective tissue underwent changes which could be associated with the release from the implants of low molecular products producing a damaging effect on the tissues surrounding the implant.

Animals