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At least 37 records · Page 2Linked to original sources
PubMed1991

[Ultrastructural changes in the adenohypophysis-thyroid system in chronic poisoning by the herbicide linuron].

Ultrastructural adenohypophysis-thyroid system investigation of Wistar male rats under conditions of chronic poisoning by Linuron herbicide and administration of thymohemin immunomodulator was performed. The release of thyrocyte fragments into the vascular lumen, electron-dense deposits in the area of vascular basal membrane, dilatation of endoplasmic reticulum cisternae as well as inhibition of Golgi complex in thyrocytes are observed in the thyroid exposed to Linuron; in the adenohypophysis under the same conditions swelling and splitting of microvessel basal membrane as well as the increase of biosynthetic and secretory thyrotrophic function can be seen. Thymohemin reduces the degree of degenerative processes in the thyroid gland.

Adjuvants, Immunologic↗
PubMed1990

[The immunomorphological characteristics of prolonged exposure to the herbicide linuron].

The authors investigated the effect of long-term use of the herbicide linuron on the histo- and ultrastructure of the thymus and factors of immunological defense. It was found that the use of linuron in animals resulted in development of secondary immunodeficiency states manifested in pathology of the thymic structure, first of all lesions of the epithelial cells-feeders and disorders of immunological indices.

Animals↗
PubMed1984

3,3',4,4'-Tetrachloroazobenzene and 3,3',4,4'-tetrachloroazoxybenzene in technical grade herbicides: propanil, diuron, linuron, and neburon.

The levels of 3,3',4,4'-tetrachloroazobenzene (TCAB) and 3,3',4,4'-tetrachloroazoxybenzene (TCAOB) were determined by gas chromatography-electron capture detection in 20 samples of 3,4-dichloroaniline-derived herbicides. The concentrations of TCAB in technical grade propanil, diuron, linuron, and neburon from a variety of manufacturers ranged from 0.10 to 28.40 mg/kg. No relevant difference was found between the two different herbicide classes analyzed.

Azo Compounds↗
PubMedDate not supplied

[Linuron breakdown by fungi of the genus Aspergillus].

Aspergillus flavus isolated from soil as well as museum cultures from the genus Aspergillus transform linuron to 3,4-dichloroaniline by the reaction of demethylation with following hydrolysis of the amide bond; 3,4-dichloroaniline is then acetylated yielding 3,4-dichloroacetanilide. These products regulate the enzymes involved in demethylation and hydrolytic elimination of the side chain. Carbon sources added to a buffer mixture inhibit decomposition of the side chain.

Acetylation↗
PubMedDate not supplied

[An immunological and morphological study of focal staphylococcal infection against a background of long-term exposure to the herbicide linuron].

Small doses of long-term injection of herbicide linuron causes the appearance of secondary immunodeficiency. It is manifested in histological and ultrastructural determination of thymus, severe suppression of immunological indices. Epithelial nurse-cells damage takes place in thymus, the contacts between epithelial cells are destroyed, the reforming of microvessels (their endothelium) occurs which causes the deterioration of vessels penetration and the growth of connective tissue. Against this background a more rapid development of experimental staphylococcus abscesses is observed in animals, the reparation phase being absent.

Abscess↗
PubMedDate not supplied

Tetrachloroazobenzene in 3,4-dichloroaniline and its herbicidal derivatives: propanil, diuron, linuron, and neburon.

The presence of 3,3', 4,4'-tetrachloroazobenzene (TCAB) was determined by high performance liquid chromatography in 3, 4-dichloroaniline and herbicides made therefrom. The concentrations of TCAB in 3, 4-dichloroanilines and in different herbicides from a variety of manufacturers ranged from 9 to 1400 micrograms/g (ppm). The chloracnegenic potential of these products, as determined by rabbit ear test, suggests that it is in the same range of 2, 3, 7, 8-tetrachlorodibenzodioxin, a known potent chloracnegenic agent.

Acne Vulgaris↗
PubMedDate not supplied

Effect of some ecological factors of degradation of propanil, linuron, and their transformation product 3,4-dichloroaniline in soil.

The degradation of xenobiotics was investigated in model experiments in soddy-podzolic soil as a function of their concentration, pH moisture content, temperature, and aeration of the soil, and presence of organic and mineral compounds. The main and secondary factors determining the persistence of xenobiotics in soil were established and approximation formulas for calculating their persistance criteria (ty) were proposed.

Anilides↗