PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Magic”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources
PubMed1986

Short-term memory capacity: magic number or magic spell?

Previous experiments have found that memory span is greater for items that can be pronounced more quickly. For a variety of materials the span equals the number of items that can be pronounced in about 1.5 s, presumably the duration of the verbal trace. This suggests a model for immediate recall: The probability of correctly recalling a list equals the probability that the time to recite the list is less than the variable duration of the trace. Recall probability for lists of various lengths was determined for six materials. Later, subjects read the lists aloud. The standard normal deviates corresponding to probability of correct recall were linear in pronunciation time. Evidently, over subjects, a normal distribution is a reasonable approximation of the distribution of the trace duration. The mean and variance of the trace duration were estimated. The mean (1.88 s) agrees well with previous estimates, and the model accounts for 95% of the variance in immediate recall.

Humans↗
PubMed2004

Labeled antigens and antibodies: the evolution of magic markers and magic bullets.

The ability to label antigens and antibodies with simple chemicals and even with whole proteins fostered new approaches to basic studies of the immune system as well as new methods of immunodiagnosis and immunotherapy. This was especially true following the introduction of monoclonal antibodies, which enhanced the specificity of many of these applications. The uses to which these labeled immunoreagents were put were legion, and those who employed them might come from any field of biology or medicine. Many of these technical elaborations were critical to progress in immunology and in many other biomedical sciences. They illustrate also the often complex interplay between technology and theory.

Animals↗
PubMed1992

Intravenous immunoglobulin therapy: magic or black magic.

Intravenous immunoglobulin (IVIG) therapy has been used not only as replacement treatment for immunodeficiency, but also as treatment of autoimmune diseases, specifically Kawasaki disease, systemic juvenile arthritis and juvenile dermatomyositis. In Kawasaki disease, IVIG reduces the incidence of coronary artery abnormalities, as well as rapidly improving clinical and laboratory variables such as fever and rash, platelet count, white blood cell count and serum albumin. Furthermore, a single high dose of 2 g/kg is as effective as 400 mg/kg x 4 days. In systemic juvenile arthritis, followup of at least one year demonstrated that monthly treatment with IVIG resulted in improvement of systemic disease in 10/11 patients, allowed for cessation of prednisone treatment in 7/8 patients and significant improvement of arthritis in 8 patients. In juvenile dermatomyositis, we report 2 uncontrolled trials of IVIG treatment that resulted in significant clinical improvement and steroid-sparing. In contrast, IVIG treatment of systemic lupus erythematosus (SLE) resulted in improvement in 3 patients, but exacerbation or new onset of renal disease in 3 patients. Overall, our report demonstrates that IVIG has been effective both in a controlled trial in Kawasaki disease and in uncontrolled trials in systemic juvenile arthritis and juvenile dermatomyositis. We suggest that IVIG should be used cautiously in SLE.

Arthritis, Juvenile↗
PubMed1994

Seeing is believing: children's explanations of commonplace, magical, and extraordinary transformations.

Children's magical explanations and beliefs were investigated in 2 studies. In Study 1, we first asked 4- and 5-year-old children to judge the possibility of certain object transformations and to suggest mechanisms that might accomplish them. We then presented several commonplace transformations (e.g., cutting a string) and impossible events (magic tricks). Prior to viewing these transformations, children suggested predominantly physical mechanisms for the events and judged the magical ones to be impossible. After seeing the impossible events, many 4-year-olds explained them as "magic," whereas 5-year-olds explained them as "tricks." In Study 2, we replaced the magic tricks with "extraordinary" events brought about by physical or chemical reactions (e.g., heat causing paint on a toy car to change color). Prior to viewing the "extraordinary" transformations, children judged them to be impossible. After viewing these events, 4-year-olds gave more magical and fewer physical explanations than did 5-year-olds. Follow-up interviews revealed that most 4-year-olds viewed magic as possible under the control of an agent (magician) with special powers, whereas most 5-year-olds viewed magic as tricks that anyone can learn. In a third study, we surveyed parents to assess their perceptions and conceptions of children's beliefs in magic and fantasy figures. Parents perceived their children as beliefs in magic and fantasy figures. Parents perceived their children as believing in a number of magic and fantasy figures and reported encouraging such beliefs to some degree. Taken together, these findings suggest that many 4-year-olds view magic as a plausible mechanism, yet reserve magical explanations for certain real world events which violate their causal expectations.

Child Development↗
PubMed2005

Magic trick: a behavioural strategy for the management of strong-willed children.

OBJECTIVE: The purpose of this study was to compare the effectiveness of using a magic trick to persuade strong-willed children who refuse to sit in the dental chair at the first visit with more conventional methods like tell-show-do (TSD). METHODS: Seventy children aged 3-6 years of age who were identified as manifesting strong-willed behaviour were selected for this study. The children were randomly assigned to be managed either by a magic trick distraction or by TSD. There were 35 subjects in each group. The following variables were recorded for each child: time from the beginning of the session to sitting on the dental chair (in minutes); ability to perform a dental examination (yes or no); and Frankl's behavioural category. RESULTS: Children who were shown a magic trick (Magic+) sat significantly faster on the dental chair than children who were not shown the magic trick (Magic-) (141.2+/-71.5 and 221.7+/-110.7 s, respectively). In addition, radiographs could be taken in significantly more Magic+ children (91% and 54%, respectively). When time till sitting on dental chair, radiographs taken and Frankl's behavioural categories were examined by gender, age, first time at the dentist and by parent assessment, the following pattern emerged: (1) Children in the Magic+ group sat on the dental chair significantly faster than children in the Magic- group. (2) Radiographs could be taken for more Magic+ children. (3) The Magic+ children demonstrated more cooperative behaviour (Frankl's categories 3 and 4). CONCLUSION: This study demonstrates that a magic trick is able to facilitate two types of cooperative behaviour: (1) it expedites the movement of the child into the dental chair; and (2) it enables the dentist to take radiographs more easily.

Attention↗
PubMed2004

Magical ideation -- defense mechanism or neuropathology? A study with multiple sclerosis patients.

BACKGROUND: The major psychological stress factor in multiple sclerosis (MS) is loss of control of life. In MS patients with impaired cognition, magical ideation might be a characteristic way of thinking. Proof for this may be the high frequency of alternative treatments used by individuals with MS. The study investigates whether the level of magical ideation in MS patients is higher compared to healthy control subjects and, in case of positive confirmation, with which somatic and psychological features it is associated. Moreover, it is aimed to discuss the modalities of magical ideation in general. SAMPLING AND METHODS: A German version of the Magical Ideation Scale was validated with a group of 69 healthy subjects. Ninety-four MS patients were additionally assessed with the Dissociative Experience Scale, the Symptom-Check-List-90-Revised and 5 neuropsychological tests. RESULTS: The Magical Ideation Scale did not reveal a significant difference between MS patients and healthy controls (p = 0.968). Among the MS patients, magical ideation shows a correlation neither with age nor with disability, but a positive correlation (p = 0.007; r = 0.329) with the grade of neuropsychological deficiency. Among the psychological parameters, the highest positive correlation with magical ideation was found in dissociation (p = 0.000; r = 0.520). DISCUSSION: Magical ideation, sharing common features with dissociation, can be viewed as an early defense mechanism when perceiving a loss of control of life, particularly in early stages of MS. In late stages, when developing neuropsychological deficits, it may occur as a substitute for cognitive coping. The data may encourage clinicians to identify magical ideation. In young and previously diagnosed patients, it is important to acknowledge helplessness and support a rather rational way of coping. Training cognitive skills could be crucial to prevent older patients from losing touch with reality. More generally, the occurrence of a significant amount of magical ideation is discussed both as a psychological and a neurophysiologic regression of thinking.

Adaptation, Psychological↗
PubMed2003

The application of psychoanalytic principles to the study of "magic".

In this paper Freud's work on animism and magic is elaborated. Those two subjects are presented mainly in his work "Totem and Taboo" (1913). The true motives, which lead primitive man to practice magic are, according to Freud, human whishes and his immense belief in their power. Importance attached to wishes and to the will has been extended from them to all those psychical acts, which are subjected to will. A general overvaluation has thus come about of all mental processes. Things become less important than ideas of things. Relations, which hold between the ideas of things, are equally hold between the things. The principle of governing magic or the technique of animistic way of thinking is one of the 'omnipotence of thoughts'. The overvaluation of psychic acts could be brought into relation with narcissism and megalomania, a belief in the thaumaturgic force of words and a technique for dealing with the external world--'magic'--which appears to be a logical application of these grandiose premises. Recent psychoanalytic authors dealing with the problem of magic emphasize that magic survived culturally to the present days and even in adults who are otherwise intellectually and scientifically 'modern'. Their explanations for that derive from Ferenczi's and especially Róheim's work that pointed out that magic facilitates adaptive and realistically effective endeavors. Balter pointed out that magic employs ego functioning, and conversely ego functioning includes magic.

Cultural Characteristics↗
PubMed2005

Magic number silicon dioxide-based clusters: laser ablation-mass spectrometric and density functional theory studies.

The magic number silica clusters [(SiO(2))(n)O(2)H(3)](-) with n = 4 and 8 have been observed in the XeCl excimer laser (308 nm) ablation of various porous siliceous materials. The structural origin of the magic number clusters has been studied by the density functional theoretical calculation at the B3LYP/6-31G** level, with a genetic algorithm as a supplementary tool for global structure searching. The DFT results of the first magic number cluster are parallel to the corresponding Hartree-Fock results previously reported with only small differences in the structural parameters. Theoretical calculation predicts that the first magic number cluster (SiO(2))(4)O(2)H(4) and its anion [(SiO(2))(4)O(2)H(3)](-) will most probably take pseudotetrahedral cage-like structures. To study the structural properties of the second magic number cluster, geometries of the bare cluster (SiO(2))(8), the neutral complex cluster (SiO(2))(8)O(2)H(4), and the anionic cluster [(SiO(2))(8)O(2)H(3)](-) are fully optimized at the B3LYP/6-31G** level, and the corresponding vibrational frequencies are calculated. The DFT calculations predict that the ground state of the bare silica octamer (SiO(2))(8) has a linear chain structure, whereas the second magic number complex cluster (SiO(2))(8)O(2)H(4) and its anion [(SiO(2))(8)O(2)H(3)](-) are most probably a mixture of cubic cage-like structural isomers with an O atom inside the cage and several quasi-bicage isomers with high intercage interactions. The stabilization of these structures can also be attributed to the active participation of the group of atoms 2O and 4H (3H for the anion) in chemical bonding during cluster formation. Our theoretical calculation gives preliminary structural interpretation of the presence of the first and second magic number clusters and the absence of higher magic numbers.

Journal Article↗
PubMedDate not supplied

[The magical worthiness of the medicines].

INTRODUCTION: The aim of this study is to demonstrate the existence of a magical valuing of the medicaments. METHODS: 32 patients were included into the study. A questionnaire in order to evaluate the magical valuing of the medicaments was used. RESULTS: Colour caused 77% magical answers with regard to the power and 65.75 connected with the tolerance. Size was responsible of 56.3% magical answers with regard to the power and 31.3% related to the tolerance. Shape justified 62.5% magical answers relate to the power and 50% connected with the tolerance. 31.1% answers reflected a magical relationship between dose and power. 75% elected the < > labelled packing claiming magical motives. CONCLUSIONS: The results obtained suggest that our patients valued medicaments in a magical way.

Adult↗
PubMed2000

The influence of flip angle on the magic angle effect.

OBJECTIVE: To assess the impact of flip angle with gradient sequences on the "magic angle effect". We characterized the magic angle effect in various gradient echo sequences and compared the signal-to-noise ratios present on these sequences with the signal-to-noise ratios of spin echo sequences. DESIGN: Ten normal healthy volunteers were positioned such that the flexor hallucis longus tendon remained at approximately at 55 degrees to the main magnetic field (the magic angle). The tendon was imaged by a conventional spin echo T1- and T2-weighted techniques and by a series of gradient techniques. Gradient sequences were altered by both TE and flip angle. Signal-to-noise measurements were obtained at segments of the flexor hallucis longus tendon demonstrating the magic angle effect to quantify the artifact. Signal-to-noise measurements were compared and statistical analysis performed. Similar measurements were taken of the anterior tibialis tendon as an internal control. RESULTS AND CONCLUSIONS: We demonstrated the magic angle effect on all the gradient sequences. The intensity of the artifact was affected by both the TE and flip angle. Low TE values and a high flip angle demonstrated the greatest magic angle effect. At TE values less than 30 ms, a high flip angle will markedly increase the magic angle effect.

Adult↗
PubMed1992

[Visagnost--a screening test for in vitro diagnosis of allergy compared with Magic Lite and Cap-FEIA. II. Allergen-specific determination of IgE].

Diagnosis of allergic diseases is based on medical history, clinical and specific tests. Although the role of specific IgE-determination used for allergy diagnosis is cleared, the technique might be expensive for routine screening. The development of a new dip-stick screening device (Visagnost Inhalationsallergien, in U.S. Quidel allergy screen) gives us the possibility of fast and easy screening without laboratory equipment. For the evaluation of the diagnostic value of Visagnost we compared the device with two modern standard laboratory techniques, Magic Lite SQ (Ciba-Corning) and CAP-FEIA (Pharmacia). We tested the most relevant allergens in Germany, in detail birch, grass, rye, ragweed, alternaria, cat, dog and the housedust mites D. pteronyssinus and D. farinae. We found a mean "RAST"-class of 1.55 (SD 1.25) for Magic Lite SQ, a mean of 1.24 (SD 1.62) for Visagnost and a mean of 1.93 (SD 1.70) for CAP-FEIA. Plotting the results for each of the examined methods, Magic Lite SQ seems to be more sensitive in lower specific IgE-levels, while CAP-FEIA gives more results of high IgE-levels, Visagnost ranging in between in general. Dividing the "RAST"-class results in the negative group of class 0 and 1 and in the positive group of class 2 and more, Visagnost revealed a sensitivity of 57% compared to CAP-FEIA and 63% to Magic Lite SQ, respectively. Specificity was 95.8% for CAP-FEIA and 90.7% for Magic Lite, while the positive predictive value for Magic Lite SQ was 87.9% and 95.7% for CAP-FEIA. Magic Lite gave a negative predictive value of 69.5% while 58.7% for CAP-FEIA.(ABSTRACT TRUNCATED AT 250 WORDS)

Allergens↗
PubMed2006

Preparation and use of 131I magic gel as a dosimeter for targeted radionuclide therapy.

Clinical interest in targeted radiotherapy is increasing, but accurate dosimetry studies are difficult to achieve. The aim of this study was to investigate the preparation and use of a "normoxic" polymer gel (with a tissue-equivalent density), known as MAGIC gel, and magnetic resonance imaging (MRI) for nonsealed source dosimetry. MAGIC gel samples were mixed with deionized water (MAGIC95) or a solution of 131I (131I-MAGIC95). By measuring the radioinduced variations of R2 values (relaxivity) of irradiated gels, we analyzed the response of MAGIC95 and MAGIC samples to external photon beam or 131I irradiation (131I-MAGIC95). MRI showed that a homogeneous dose distribution from 131I can be achieved if the MAGIC gel, at a temperature of approximately 35 degrees C, is mixed in 131I solution and the resulting mixture shaken gently for 30 minutes. It is important that the vials are completely filled, as residual air reduces polymerization and causes spontaneous polymerization stripes. Responses of MAGIC95 or MAGIC gels to external photon beam irradiation are similar. The variations of R2 values for 131I-MAGIC95 gel depend on the absorbed dose and not on the duration of the irradiation being reproducible from one batch of gel to another. MAGIC gel responses to 131I or external beam irradiation (EBI) are different. Our preliminary results suggest that radiolabeled "normoxic" polymer can be easily and safely produced. Radiolabeled MAGIC gel may, therefore, be suitable for the creation of phantoms dedicated to nonsealed source dosimetry.

Ascorbic Acid↗