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Results for “Maxillary Sinus Neoplasms”

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PubMed1998

Effect of systemic pretreatment with betamethasone on the bacterial flora, inflammatory response, and polyp formation in experimentally infected rabbit maxillary sinus mucosa.

To investigate possible effects of corticosteroids on polyp formation and local bacterial colonization, pneumococcal sinusitis was experimentally induced in rabbits pretreated with betamethasone or saline. After 7 days, macroscopic polyps were counted post-mortem and on histologic slides after serial sectioning. Histologic sections were also examined with light microscopy. Macroscopic polyps were significantly fewer in animals given betamethasone, while there was no difference regarding the number of microscopic polyps. Ingrowth of pathogenic microorganisms was found in five of eight rabbits given placebo but in none of the animals treated with corticosteroids (P < 0.05). The reduced number of pathogenic strains in these animals may be explained by a better-preserved local host defense. The lower number of macroscopic polyps in the same animals could be because of a delayed mucosal repair and subsequent polyp formation.

Animals↗
PubMed2001

Top 10 reasons for endoscopic maxillary sinus surgery failure.

OBJECTIVE/HYPOTHESIS: Endoscopic sinus surgery has enjoyed impressive success curing chronic disease in sinuses and has virtually replaced the Caldwell-Luc procedure for correction of problems with the maxillary sinus. Unfortunately, a significant number of patients have persistent maxillary symptoms after one or more endoscopic sinus operations. Existing reviews of this issue have identified only a few general causes for surgical failure. METHODS: The records of 85 patients presenting to the author over a 5-year period with persistent maxillary sinus symptoms were reviewed. RESULTS: In reviewing the causes of persistent disease requiring revision surgery, the author identified 10 categories of reasons for failure to improve. Many patients have multiple causes that could be individually or sequentially identified. Some problems associated with surgical failure were likely present at the time of initial presentation, whereas others were undoubtedly caused by the first surgical procedure. Ten reasons for maxillary sinus surgical failure identified were clustered into the following categories: 1) obstructed natural ostia, 2) disease in the anterior ethmoid or frontal sinus, 3) resistant organisms, 4) intrasinus foreign body, 5) incurable mucosal disease, 6) noncompliant patient, 7) wrong primary diagnosis, 8) maxillary osteitis, 9) mucus maltransport, and 10) fundamental immunodeficiency. CONCLUSIONS: A careful assessment of each patient with persistent maxillary sinus disease is central to understanding each specific patient and should include a careful history, a detailed endoscopic examination, repeat computed tomography imaging, culture of secretions, and possible revision surgery.

Endoscopy↗
PubMed2005

Opaque maxillary antrum: a pictorial review.

The demonstration of an opaque antrum on a plain radiograph or cross-sectional imaging leads to consideration of an extensive differential diagnosis. Relevant clinical details narrow the differential and include the patient's age, signs and symptoms, a history of recent trauma, prior surgery or dental treatment. Computed tomography remains the most useful technique in coming to a specific diagnosis. Magnetic resonance imaging adds specificity in a few selected situations and is required in conjunction with CT in the staging of malignant tumours.

Diagnosis, Differential↗
PubMed1993

Formation of mucosal polyps in the nasal and maxillary sinus cavities by infection.

Unilateral maxillary sinusitis was experimentally induced in New Zealand White rabbits with Streptococcus pneumoniae serotype 3, Bacteroides fragilis NCTC 9343, and Staphylococcus aureus V8. In another group of rabbits, sinusitis was induced by blocking of the sinus ostium only. Bacteriologic and light microscopic analysis was performed after 5 days to 1 month. Granulation-like polyps developed after deep mucosal inflammatory trauma initiating fibroblast proliferation, angiogenesis, and epithelial migration to cover the polyp. In regions of a more superficial trauma-characterized by epithelial desquamation and fibroblast growth-proliferation and differentiation of basal cells resulted in the formation of microcavities dissecting off edematous polyps. Polyps could be found in all sinusitis groups, irrespective of inducing agent. The cellular events of polyp formation appear to be the result of a continuous inflammatory reaction and are not directly related to the presence of a certain microorganism. Instead, the potential of any microorganism to induce a deep mucosal trauma or epithelial desquamation seems essential for its ability to initiate polyp formation.

Animals↗
PubMed2004

[Clinical study of routes of onset of inflammatory diseases in the maxillary sinuses].

Pathways of the maxillary sinus diseases is an interesting issue investigated by many authors during the past decades. The goal of this research was to study the pathways of infection spreading into the maxillary sinuses and to compare them in relation to their frequency, underlying causes and general epidemiologic characteristics of the involved population. A total number of 150 adult patients of both gender suffering different diseases of maxillary sinuses were included into the study. Pathways rising maxillary sinuses diseases were diagnosed on the basis of standard clinical procedures including CT scean and MRI of the region. We found inflammatory processes to dominate the tumorous ones (107:43 patients). Rhinogenic type of sinusitis was the most frequent disease (72 patients) while odontogenic sinusitis (35 patients) was significantly less frequent. No case of traumatic or hematogenic maxillary sinusitis was found. Rhinogenic maxillary sinusitis is characterised by spontaneous onset while odontogenic one is mostly of arteficial origin after surgical procedures in the oral cavity (88% of patients). In contrast to rhinogenic type, odontogenic maxillary sinusitis is far more frequent in younger patients.

Female↗
PubMedDate not supplied

Molecular profile of the antrochoanal polyp: up-regulation of basic fibroblast growth factor and transforming growth factor beta in maxillary sinus mucosa.

BACKGROUND: Various pathogenetic mechanisms have been proposed to explain the development of antrochoanal polyps (ACPs); however, the cause is still largely unknown. The aim of this study was to characterize the expression and the potential role of a battery of molecular markers in the development of ACPs. A prospective controlled study of a case series was performed. METHODS: Tissue samples of maxillary sinus mucosa were obtained from 14 patients with ACPs, 17 patients with chronic nonpolypoid maxillary sinusitis, and 4 patients with normal maxillary sinus mucosa; RNAs were extracted from the sinus mucosa, and semiquantitative reverse transcription-polymerase chain reaction was performed for basic fibroblast growth factor, transforming growth factor P, and mucin genes (MUC), MUC5AC, MUC5B, and MUC8, to investigate their expression. RESULTS: The expression of basic fibroblast growth factor and transforming growth factor beta was significantly higher in ACPs than in chronic rhinosinusitis and healthy mucosa. Meanwhile, the levels of expression of MUC genes were higher in ACPs and chronic rhinosinusitis compared with healthy mucosa. CONCLUSION: These findings suggest that ACPs may represent an inflammatory reaction caused by overproduction of tissue-derived growth factors in an inductive environment.

Adult↗
PubMed1997

Radiological findings in the maxillary sinuses of symptomless young men.

The maxillary sinuses were examined radiologically by occipitomental projection (Waters' view) in 404 conscripts without any symptoms of sinusitis. Abnormalities were found in 188 (23.3%) of all 808 sinuses, the most common being mucosal thickening of > 6 mm (12.3% of the sinuses), cysts or polyps (7.2%), and completely opacified sinus (3.3%). Normal x-ray findings were more common in the conscripts examined during the summer months and mucosal thickening was more frequently encountered in winter than in summer. Nasal bacteria were studied in 100 cases. Findings of normal bacterial flora and of pathogenic bacteria were equally frequent among subjects with normal sinus x-ray (score 0 and 1) and subjects with severe abnormalities (scores 3-6), but mucosal cysts (score 2) was more often combined with pathogens in the nose. Mucosal thickening was more often observed in non-allergic than in allergic persons; thus allergy did not seem to increase radiological abnormalities. Of young men engaged in outdoor activities, about one fifth seem to have significant chronic mucous membrane abnormalities in the maxillary antra without clinical symptoms. In 1-2% of cases secretion is detected in the maxillary sinus indicating a subclinical sinusitis.

Adult↗
PubMed1997

[CT diagnosis of maxillary sinus diseases].

To evaluate the diagnostic value of CT scan in maxillary sinus diseases, CT findings in 100 cases of maxillary sinus diseases, which included 64 inflammatory diseases; 14 benign tumors; 17 malignant tumors and 5 fractures The result showed that the accordance rate between CT scan and operative diagnosis was 95.0%; between CT scan and pathology was 92.6%(88/95). It is concluded that CT scan showed a better visualization of maxillary sinus than X-ray tomogram.

Adolescent↗
PubMedDate not supplied

[Pansinusitis secondary to inflammatory myofibroblastic tumor].

Inflammatory myofibroblastic tumors are aetiologically enigmatic and biologically unpredictable lesions. The lungs are the organs of apparent predilection. These tumors have also been documented in a number of extrapulmonary sites including head and neck. Paranasal location is rare. We report a case of a maxillary location in a 10 years and 10 months old girl initiated as an acute pansinusitis.

Child↗
PubMed2001

[Experimental study of endosurgical approaches to maxillary sinuses].

Studies on 30 cadavers were carried out in order to develop endoscopic approaches to diagnosis and treatment of inflammatory and tumorous diseases of the maxillary sinuses. Morphometric data helped objectively validate surgical accesses and experimentally confirmed the efficiency of three accesses: from the maxillary tuber, through the anterior wall, and through the inferior nasal passage. Endosurgical approaches allow radical operations with minimum injury and ensure functional and esthetic effects.

Humans↗
PubMed2001

[Modern endosurgical technologies in the diagnosis and treatment of maxillary inflammations and tumors (part 2)].

A total of 102 patients with inflammatory diseases and tumors of the maxillary sinuses were examined and treated using endosurgical technologies. X-Ray computer-aided tomography and magnetic imaging helped determine the access to the maxillary sinus, and the endosurgical instrument was inserted through the anterior wall of the sinus, medial wall, and maxillary tuberosity. Endosurgery was the most effective in polypous sinusitis, mucocele, inverted papilloma, and for biopsy. Endosurgical technologies allow a full-scale surgical intervention with the least invasion.

Adult↗
PubMed1999

[Experimental and clinic study of the maxillary sinus plasty following Caldwell-Luc].

OBJECTIVE: To investigate the clinical effect of surgical procedures on patients with chronic maxillary sinus disease. METHOD: On the basis of experimental study with animal, this prospective study included 63 patients with chronic maxillary sinus disease who had a maxillary sinus plasty following Caldwell-Luc. The operation procedures included anterior wall ring-drilling, and middle meatal antrostomy as well as sinus wall plasty. RESULT: Experimental results showed that the repair and regeneration of maxillary sinus mucosa was intact in dogs after 5 weeks of radical operation. Clinical study indicated that the condition of anterior wall with a resutured bone-lid was normalized radiographically during the follow up time of 1-3 months. The patency rate of the middle meateal antrostomy 18-42 months post-operatively (average 28 months) is 96%. CONCLUSION: We conclude from the study that the maxillary sinus plasty recovers anatomic construction, maintains physiological drainage way and provides a good environment for repair and regeneration of the sinus mucosa.

Adolescent↗
PubMed1992

Unusual presentation of verrucous carcinoma of maxillary antrum.

Verrucous carcinoma is a rare type of squamous cell carcinoma that is most often seen in the oral cavity and larynx. This paper describes a case report of a rare tumor with an unusual presentation. This patient presented with recurrent pyoceles and was diagnosed by chance. Carcinoma of maxilla is rarely diagnosed until the bony walls are eroded. This condition should be kept in mind in patients presenting with recurrent pyocele and a biopsy carried out from the maxilla.

Carcinoma, Papillary↗
PubMedDate not supplied

[Angiolipoma of the maxillary sinus as a cause of recurring sinusitis-like symptoms].

A review of the literature shows that intraoral lipomas are more common than they are generally believed to be. The clinical course of a case with unusual localization, size and clinical manifestation of an angiolipoma of the maxillary sinus is described. Differential diagnosis with other types of intraoral lipomas is made.

Adult↗
PubMedDate not supplied

[Use of echography in pathology of the maxillary sinuses].

Sonography has recently gained attention as a non-invasive technique improving the diagnostic accuracy of conventional radiology as regards the pathologic conditions of the maxillary sinus. Eighty-two patients with various pathologies of the maxillary sinus--i.e. acute/chronic sinusitis, mucocele, mucopyocele, polyp, and carcinoma--were submitted to US after preliminary conventional radiographs and before CT and surgical treatment (both performed in selected cases only). US proved useful in detecting liquid exudate, mucosal hypertrophy, and lesions of the anterior wall, while it was not as accurate in detecting lesions of the posterior wall (unless fluid was present) and in establishing the nature of a solid lesion. The last two conditions are those where CT is mainly indicated.

Diagnosis, Differential↗
PubMed1995

[Use of A-mode ultrasound in the diagnosis of maxillary sinus diseases].

This paper reported our recent attempt to utilize the nasal ultrasonography (ECHO-TE-11) in the diagnosis of maxillary sinus diseases. We performed nasal ultrasonography on 160 individuals (69 with normal maxillary sinus; 91 with chronic maxillary sinus diseases). In the normal maxillary sinus group, the proportion of diagnostic accuracy was 89.9% (62/69) and in the maxillary sinusitis group, the proportion was 91.9% (80/87). 4 cases, including postoperative maxillary cyst, benign tumor and malignant tumor of the maxillary sinus, could be accurately diagnosed by this technique. The precautions were also discussed.

Adolescent↗