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Evidence for a generalized Laguerre transform of temporal events by the visual system.

It is generally assumed that the early visual processing is constituted by a set of filters operating in parallel. In this respect the visual system performs a transform, generating a code of the characteristics of the input signal. Recently, it has been suggested that the coding of the spatial characteristics by the visual system can be described by a Hermite transform (Martens, 1990a, b). It was also suggested that a three-dimensional Hermite transform can be used to code spatiotemporal events. In contrast to this latter suggestion, we argue that the coding of temporal events takes the form of a generalized Laguerre transform. We review psychophysical evidence supporting this hypothesis.

Algorithms

A computational model of four regions of the cerebellum based on feedback-error learning.

We propose a computationally coherent model of cerebellar motor learning based on the feedback-error-learning scheme. We assume that climbing fiber responses represent motor-command errors generated by some of the premotor networks such as the feedback controllers at the spinal-, brain stem- and cerebral levels. Thus, in our model, climbing fiber responses are considered to convey motor errors in the motor-command coordinates rather than in the sensory coordinates. Based on the long-term depression in Purkinje cells each corticonuclear microcomplex in different regions of the cerebellum learns to execute predictive and coordinative control of different types of movements. Ultimately, it acquires an inverse model of a specific controlled object and complements crude control by the premotor networks. This general model is developed in detail as a specific neural circuit model for the lateral hemisphere. A new experiment is suggested to elucidate the coordinate frame in which climbing fiber responses are represented.

Animals

Adaptive feedback control models of the vestibulocerebellum and spinocerebellum.

We extend the cerebellar learning model proposed by Kawato and Gomi (1992) to the case where a specific region of the cerebellum executes adaptive feedback control as well as feedforward control. The model is still based on the feedback-error-learning scheme. The proposed adaptive feedback control model is developed in detail as a specific neural circuit model for three different regions of the cerebellum and the learning of the corresponding representative movements: (i) the flocculus and adaptive modification of the vestibulo-ocular reflex and optokinetic eye-movement responses, (ii) the vermis and adaptive posture control, and (iii) the intermediate zones of the hemisphere and adaptive control of locomotion. As a representative example, simultaneous adaptation of the vestibulo-ocular reflex and the optokinetic eye-movement response was successfully simulated while the Purkinje cells receive copies of motor commands through recurrent neural connections as well as vestibular and retinal-slip parallel-fiber inputs.

Animals

The relationship between short-term memory capacity and EEG power spectral density.

Multiplying memory span by mental speed, we obtain the information entropy of short-term memory capacity, which is rate-limiting for cognitive functions and corresponds with EEG power spectral density. The number of EEG harmonics (n = 1, 2,..., 9) is identical with memory span, and the eigenvalues of the EEG impulse response are represented by the zero-crossings up to the convolved fundamental, the P300. In analogy to quantum mechanics the brain seems to be an ideal detector simply measuring the energy of wave forms. No matter what the stimulus is and how the brain behaves, the metric of signal and memory can always be understood as a superposition of n pi states of different energy and their eigenvalues.

Brain

A self-organising neural network model of image velocity encoding.

A self-organising neural network has been developed which maps the image velocities of rigid objects, moving in the fronto-parallel plane, topologically over a neural layer. The input is information in the Fourier domain about the spatial components of the image. The computation performed by the network may be viewed as a neural instantiation of the Intersection of Constraints solution to the aperture problem. The model has biological plausibility in that the connectivity develops simply as a result of exposure to inputs derived from rigid translation of textures and its overall organisation is consistent with psychophysical evidence.

Animals

The parameter identification problem for the somatic shunt model.

The somatic shunt model, a generalized version of the Rall equivalent cylinder model, is used commonly to describe the passive electrotonic properties of neurons. Procedures for determining the parameters of the somatic shunt model that best describe a given neuron typically rely on the response of the cell to a small step of hyperpolarizing current injected by an intrasomatic recording electrode. In this study it is shown that the problem of estimating model parameters for the somatic shunt model using physiological data is ill-posed, in that very small errors in measured data can lead to large and unpredictable errors in parameter estimates. If the somatic shunt is assumed to be a real property of the intact neuron, the effects of these errors are not severe when predicting EPSP waveshapes resulting from synaptic input at a given location. However, if the somatic shunt is assumed to be a consequence of a leakage pathway around the recording electrode, and a correction for the shunt is applied, then the instability of the inverse problem can introduce large errors in estimates of EPSP waveshape as a function of synaptic location in the intact cell. Morphological constraints can be used to improve the accuracy of the inversion procedure in terms of both parameter estimates and predicted EPSP responses.

Mathematics

Sequential configuration model for firing patterns in local neural networks.

This paper presents a sequential configuration model to represent the coordinated firing patterns of memory traces in groups of neurons in local networks. Computer simulations are used to study the dynamic properties of memory traces selectively retrieved from networks in which multiple memory traces have been embedded according to the sequential configuration model. Distinct memory traces which utilize the same neurons, but differ only in temporal sequencing are selectively retrievable. Firing patterns of constituent neurons of retrieved memory traces exhibit the main properties of neurons observed in multi microelectrode recordings. The paper shows how to adjust relative synaptic weightings so as to control the disruptive influences of cross-talk in multipy-embedded networks. The theoretical distinction between (primarily anatomical) beds and (primarily physiological) realizations underlines the fundamentally stochastic nature of network firing patterns, and allows the definition of 4 degrees of clarity of retrieved memory traces.

Animals

Cross-talk theory of memory capacity in neural networks.

The present paper presents a theory for the mechanics of cross-talk among constituent neurons in networks in which multiple memory traces have been embedded, and develops criteria for memory capacity based on the disruptive influences of this cross-talk. The theory is based on interconnection patterns defined by the sequential configuration model of dynamic firing patterns. The theory accurately predicts the memory capacities observed in computer simulated nets, and predicts that cortical-like modules should be able to store up to about 300-900 selectively retrievable memory traces before disruption by cross-talk is likely. It also predicts that the cortex may has designed itself for modules of 30,000 neurons to at least in part to optimize memory capacity.

Animals

Symbolic grouping versus simple cell models.

The apparent line-like structure in dot patterns derives substantially from the orientation defined by pairings of adjacent dots. Two alternative models have been proposed for making these pairings, one in which the individual dots are treated as discrete grouping tokens, and the second in which the pairing orientation derives from spatial summation by simple cell receptive fields. Contradictory evidence has been found both directly in support of, and directly against, both models. Much of the debate about these two models has hinged on the degree of linearity of summation expected in the simple cell model. Recent neurophysiological evidence changes the balance of the debate, invalidating certain earlier arguments based on linearity and providing a model way of showing that simple cells do indeed play a major, but not necessarily exclusive, role in dot groupings.

Analysis of Variance

Dead zone for express saccades.

The saccadic eye movements of three humans and one non-human primate (a male rhesus monkey) have been measured for target eccentricities between 0.3 and 15 deg. With a gap task (fixation point offset precedes target onset by 200 ms) and a target at 4 deg, all subjects produced reasonable amounts of express saccades as indicated by a clear peak in the distribution of their saccadic reaction times (SRT): about 100 ms in human subjects and 70 ms in the monkey. This peak disappeared with decreasing target eccentricity below 2 deg, but saccades of longer (regular) reaction times were still present. Thus it was found that there exists a dead zone for express saccades. In addition, small saccades have a much stronger tendency to overshoot the target and their velocity falls above the main sequence as defined by the least square fit of an exponential v = vo(1-exp(-a/ao)) to the maximal velocity (v) versus amplitude (a) relationship (vo and ao are constants fitted). It is concluded that for small saccades the express way is blocked functionally or does not exist anatomically.

Animals

A unified model for the combined temporal and spatial Broca-Sulzer effect.

A briefly pulsed light is brighter than a pulse of longer duration. For a brief flash of fixed duration and small area, enlarging a target results initially in an increase in brightness. Beyond some critical area, the target dims with further increases in size. These two phenomena are the temporal and the spatial Broca-Sulzer effect respectively. Each effect can be modeled using a generalization of the Hartline-Ratliff equation. The resulting analysis produces a mathematically unified treatment of both effects.

Humans

A model for processing of movement in the visual system.

Processing of spatio-temporal information in the human visual system has been investigated thoroughly during the past decade, but is still far from being properly understood. Moreover, the theory of separation of information by means of sustained and transient channels already at the retinal level is not satisfactory, as experimental results indicate that these two types of channels span a continuum of temporal characteristics. It is however obvious, that the process of pattern recognition and velocity perception calls for their separation at some level of the hierarchy. In this communication, we extend our model of three-dimensional spatio-temporal frequency expansion in the visual system (Gafni and Zeevi, 1977) to show how velocity-information extraction channels, sensitive to direction and velocity exclusively, can be formed by simple summation of signals from well-defined sets of channels representing points in the frequency space. Correspondence of these channels to characteristics of the cortical neurons is discussed.

Depth Perception

Studies on human finger tapping neural networks by phase transition curves.

The human finger tapping was studied psychologically by the phase transition curves. We assumed that some oscillatory neural network controls the tapping. One of our future works on the human finger tapping is to devise a method to change the magnitude of perturbation continuously in phase resetting experiments of a constant tapping interval with a same kind of task. If this is achieved, we can obtain a phase transition surface (i.e. the new phase as a function of the old phase and the magnitude of perturbation). From the shape of a phase transition surface, the intrinsic properties of the oscillatory network which controls the tapping can be studied (Kawato et al., 1978).

Conditioning, Psychological

Sensitivity variations in the visual system, contrast resolution and eye movements.

Attention is drawn to the fact that under normal visual conditions the sensitivity of the receptor units of the visual system are subject to spatial and temporal variations, and that consequently in performing pattern recognition the visual cortex has to discriminate between external luminance structure and internal sensitivity structure. It is suggested that eye movements are the method by which this discrimination is performed. In a simplified model analysis it is shown that eye movements are a suitable mechanism for this discrimination. Implications of this model for detection threshold and stabilized retinal images are discussed. A new interpretation of the adaptation to sine wave grids is given.

Eye Movements

Analysis of recall and recognition in a certain class of adaptive networks.

A general model of adaptive networks which perform recall is analyzed in view of qualitative psychological findings. The assumptions underlying the basic model are few and general in the sense that no specifications of structure or mechanisms of adaptation are imposed. The analysis of the model is towards the addition of various features drawn from the global input-output relations expected from the networks. The memorizing process of recognition is found to be intrinsic to the model, and four of the most prominent relations between the performance of recall and recognition are shown to either exist in model or to be realizable by means of few additional plausible features.

Association Learning

Initial processing of visual information within the retina and the LGN.

The initial stage of information processing by the visual system reduces the information contained in the continuous image on the retina into a discrete set of responses which are carried from the lateral geniculate nucleus (LGN) to the visual cortex. -- 1. The optimal sampling of the light intensity distribution in the visual environment is achieved only if each channel in the visual pathways carries undistorted information corresponding to an image element. The visual system approaches as closely as possible the scheme of optimal spatial sampling, retaining the full information on the low spatial frequency content of the object light intensity. The ideal receptive field of a sustained LGN cell is then of the form J1(Kr)/Kr. -- 2. The experimentally determined receptive fields of sustained LGN cells (and to some extent retinal ganglion cells as well) in cat closely resemble the functional form J1(Kr)/Kr. The centre-surround organization of the receptive fields is therefore understood as a scheme which leads to a maximal information flow through the visual pathways. -- 3. The optimal sampling scheme cannot be realized by the retina alone, because of restrictions on the size of neural networks. It is therefore constructed in two stages, ending at the LGN level. A recombination of ganglion cell signals into optimal receptive fields is a major role of the LGN.

Animals

[Three basic kinds of behaviour, a scheme of their neurobiological correlates (author's transl)].

The psychic sphere is to be regarded as the source of meaningful behaviour, which is carried out in the service of the cell community that makes up our body. Three fundamental types of behaviour can be distinguished: the purely practical, the theoretical-practical, and the purely theoretical. These three types of behaviour have three different reasons: the first a determining reason, the second a motivating reason, and the third a supporting reason. The threefold nature of the reasons is related to the threefold needs of the cell community (in this context man is considered as an example of an animal). Possible neurobiological bases of human behaviour are depicted in a schematic figure showing the relation of cerebral centres and sensorimotor functions of the human face including eye movements. The psychic centre may be located in the thalamus, the areas of the central sulcus are regarded as an objectivation zone. This indicates that the motor zones of the cortex, including the frontal adversive fields, are intention zones, and the sensory zones reproduction, expectation, and recollection zones. A system so composed would render possible what we see in every animal being: decision-making, foresight, and learning.

Behavior