PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Motion Sickness”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources
PubMed1978

Increased urinary excretion of triiodothyronine (T3) and thyroxine (T4) and decreased serum thyreotropic hormone (TSH) induced by motion sickness.

We exposed 35 male subjects to a rotary chair and motion sickness was provoked by Coriolis effect. This stress caused an increased excretion of urinary T3 and T4 and a decrease of TSH levels in serum. The increment in urinary excretion of thyroid hormones may serve as a very useful measure for the quantitation of physical stress. Although no statistically significant change of T3, T4, and TBG levels in serum could be observed by the employed techniques, the hypothesis is favoured that motion sickness probably causes an immeasurably small increase of the free thyroid hormone fraction in serum, thereby increasing urinary excretion of T3 and T4 and, in turn, decreasing TSH secretion. Physical or psychological stress situations involve most of the endocrine systems. Contadictory results have been reported in the literature concerning the relationship between thyroid function and stress.

Epinephrine↗
PubMed1977

Some psychological correlates of motion sickness susceptibility.

Four groups of 37 subjects each (highly susceptible men, highly susceptible women, nonsusceptible men, and nonsusceptible women) were obtained from a population of 2,432 college students ranging in age from 18 to 39 years. Susceptibility to motion sickness was determined by scores on a motion sickness questionnaire (MSQ); only individuals with extreme scores were considered for inclusion in the experimental groups. The following tests were administered: Floor Ataxia Test Battery, State-Trait Anxiety Inventory, Menstrual Distress Questionnaire, Cornell Medical Index, Cornell Work Form, Eysenck Personality Inventory, Rotter Internal-External Locus of Control Scale, and the 16 Personality Factors test. Each subject was tested on at least three, but not more than six, of the eight tests. Significant sex differences were obtained on the ataxia battery and the Cornell Medical Index. Susceptible subjects did not differ significantly from nonsusceptibles on the ataxia battery but did differ significantly on all personality tests except the Menstrual Distress Questionnaire (administered only to women) and the Rotter Scale. The generally consistent and significant patterns of results from the psychological tests probably reflect the selection factors used in defining the subject groups; certain personality characteristics are associated with a high degree of susceptibility to motion sickness.

Adolescent↗
PubMed1978

Motion sickness susceptibility: a retrospective comparison of laboratory tests.

A test battery designed primarily to assess vestibular function has been used for several years to evaluate individuals referred to our laboratory. Because some of the test conditions have proved to be nauseogenic to some individuals, methods of assessing disturbance during these procedures have been used to pursue a second goal, viz., the estimation of motion sickness susceptibility. This report, which focuses on the latter goal, is a retrospective comparison of results on three tests obtained from two groups of subjects, one of which was a group of Navy and Marine aviation personnel who had suffered multiple attacks of airsickness. Results from three laboratory tests of motion sickness susceptibility indicated that there are substantial differences between the airsick group and the unselected comparison group on observer ratings and individual self-ratings of motion sickness symptoms. The provocative stimuli in each laboratory test, as well as suggestions concerning how multiple tests may prove effective in predicting motion sickness, are discussed.

Aerospace Medicine↗
PubMedDate not supplied

[Model of motion sickness in dogs for assessing the effectiveness of pharmacological substances].

The paper describes a model of motion sickness for dogs. The method is based on the simultaneous use of vertical and rotatory movement of the device with a continuously varying angular velocity of rotation to generate Coriolis acceleration. The exposure increases significantly the number of sick animals to be used in the selection of antimotion drugs. Diphenidol, marezine, tigane, bromotigane and metachloropromide were tested. Diphenidol and to a lesser extent marezine and metachloropromide proved effective. Tigane and bromotigane were ineffective against motion sickness.

Animals↗
PubMed1977

Comparison of susceptibility to motion sickness during rotation at 30 rpm in the earth-horizontal, 10 degrees head-up, and 10 degrees head-down positions.

Normal persons rotated about an Earth-horizontal axis vary in their susceptibility to motion sickness. The purpose of this experiment was to measure, intraindividual differences in susceptibility in 12 subjects when rotated 10 degrees head up and 10 degrees head down as well as in the horizontal position. Subjects assumed the test-position 60 min prior to rotation, thus providing an opportunity for translocation of body fluids. Physiological and psychophysical measurements were conducted throughout the experiment. There were no intraindividual differences in susceptibility to motion sickness in the three positions tested, although there were significant differences in vital capacity, demonstrating the expected fluid shifts. It was concluded that, in the sample of subjects tested, short-term effects of fluid shifts greater than those that would be manifested in zero gravity had no definite effect on motion sickness susceptibility.

Adult↗
PubMed1979

[Motion sickness (author's transl)].

A short introduction to motion sickness is followed by a historical survey of the various theories, with special reference to those concerning the inner ear. The symptomatology and the consequences of the disease are discussed. Prevention and therapy are considered.

Adaptation, Physiological↗
PubMed1975

Postural behavior and motion sickness.

(1) An interesting style of acting was demonstrated on a stage of a Kyogen, a classic comedy of Japan, titled "Funawatashimuko", i.e., "A boatman and a bridgegroom in a boat". Antagonistic postures which move toward the opposite direction were displayed by a boatman who is pulling an oar and a passenger who is being moved by the rolling of a boat. (2) Why doesn't one suffer from motion sickness when he drives a car but may suffer from it when he is a passenger? This question was answered, from the standpoint of human postures, by observing the antagonistic postures exhibited by a bus-driver and a passenger, and also by the findings in postrotatory eye nystagmus (an indication of artificial motion sickness) which was varied according to the three different positions of the head. (3) Learning postural adjustment against motion sickness, developing through repetitively traveling in vehicles, was also objectively shown in a posture of an experienced lady bus-conductor whose body inclined in the same direction as that of the driver. Its similarity to the establishment of a kinetic labyrinthine reflex in chickens was explained.

Animals↗
PubMedDate not supplied

Postural behaviour and motion sickness.

One of the acting techniques used in Kyogen, a classical Japanese stage comedy, prompted two questions: why is it that one may suffer from motion sickness as a car passenger, but, as a driver, escape its effects? And how can one learn postural adjustment against motion sickness by repeatedly travelling in vehicles?

Adaptation, Physiological↗
PubMed1979

Estimated body rotation as a predictor of motion sickness susceptibility.

We rotated 36 blindfolded subjects in yaw between 30 degrees and 135 degrees and asked them to estimate the angular displacement they had experienced. An index of a subject's "receptivity" was obtained by calculating the slope of the line relating perceived to actual displacement; his susceptibility to motion sickness was determined by a questionnaire. The product moment correlation between these two measures was not significant, a result which conflicts with the receptivity hypothesis. It is suggested that "adaptability" rather than "receptivity" may be the more impotant determinant of susceptibility to motion sickness.

Adult↗
PubMed1977

Susceptibility to motion sickness and ego closeness, ego distance as measured by the autokinetic response tendency.

This paper reports results from one phase in an ongoing study of the relationship between vestibular function and various aspects of personality, cognitive style and symptom formation in mental illness. In the experiment reported here a measure of autokinesis was shown to relate to motion sickness experience as judged by actual stimulation in a rotating chair. Low and intermediate sensitive subjects showed less autokinesis than the most motion sick individuals (two-way analysis of variance F = 5.735, P = 0.006). Males in this sample showed a significantly greater autokinetic tendency than females (two-way analysis of variance F = 6.995, P = 0.011).

Adult↗
PubMed1977

Motion sickness: an evolutionary hypothesis.

Since the occurrence of vomiting as a response to motion is both widespread and apparently disadvantageous, it presents a problem for evolutionary theory. An hypothesis is proposed suggesting that motion sickness is triggered by difficulties which arise in the programming of movements of the eyes or head when the relations between the spatial frameworks defined by the visual, vestibular, or proprioceptive inputs are repeatedly and unpredictably perturbed. Such perturbations may be produced by certain types of motion, or by disturbances in sensory input or motor control produced by ingested toxins. The last would be the important cause in nature, the main function of the emesis being to rid the individual of ingested neurotoxins. Its occurrence in response to motion would be an accidental by product of this system.

Age Factors↗
PubMed1979

Effect of transdermally administered scopolamine in preventing motion sickness.

The efficacy of transdermally administered scopolamine was compared with the efficacy of oral dimenhydrinate and placebo therapy in the prevention of motion-induced mausea in a vertical oscillator; medications were administered on a double-blind cross-over basis, with the order of treatments counterbalanced. Thirty-five subjects known to be susceptible to the stimulus were utilized. A placebo effect reduced the motion sickness incidence (MSI) from 100% to 59%. Administration of dimenhydrinate reduced the MSI to 32%, and use of the transdermal therapeutic system scopolamine (TTS-scopolamine) further reduced the MSI TO 16%. TTS-scopolamine afforded 73% protection against motion-induced nausea, compared to 46% protection with dimenhydrinate. The TTS-scopolamine is designed to remain in the body for 72 hours, providing advantages over intramuscular or oral administration of scopolamine, which include reduced daily dosage, and an effective alternate to the gastrointestinal tract for administrating medication at times of gastrointestinal distress.

Administration, Topical↗
PubMed1979

Motion sickness: an index of sensory conflict relating to behavior.

Diverse measures of behavior are examined in a student and large patient sample for the purpose of supporting the concept that conflict in sensory mechanisms may contribute to diminished or impaired function. Evidence supports the contention that two patterns of orientation may exist at the extremes of motion sickness susceptibility and that individuals showing transitional patterns of organization may be vulnerable to different kinds of central nervous system disorganization. The authors believe that a consideration of sensory function as it relates to patterns of behavior may contribute to an expansion in the medical model of mental illness.

Adolescent↗
PubMed1979

Motion sickness in cats: a symptom rating scale used in laboratory and flight tests.

The cat is proposed as a model for the study of motion and space sickness. Development of a scale for rating the motion sickness severity in the cat is described. The scale is used to evaluate an antimotion sickness drug, d-amphetamine plus scopolamine, and to determine whether it is possible to predict sickness susceptibility during parabolic flight, including zero-G maneuvers, from scores obtained during ground based trials.

Aerospace Medicine↗
PubMed1976

Prevention of experimental motion sickness by scopolamine absorbed through the skin.

A double-blind placebo-controlled study compared the efficacy of the antimotion sickness drug scopolamine when administered by oral or transdermal routes. A secondary purpose was to extend our bioassay involving fixed-dose combinations of the homergic drugs promethazine and ephedrine. After receiving 12 apparently identical drug-placebo treatments, eight normal male students were exposed to a slow rotation room to stressful accelerations generated by their execution of 40 head movements out of the plane of the room's rotation of 1 rpm and at 1-rpm increments until either symptoms were experienced (just short of frank motion sickness) or the 27-rpm ceiling on the test was reached. Efficacy of a drug was defined in terms of the placeborange and categorized as beneficial, inconsequential, or detrimental. The rank order of drugs with beneficial effects was: 1) promethazine 25 mg plus ephedrine 12.5 mg (86%); 2) scopolamine by mouth (75%); 3) scopolamine transdermally (63%); and 4) promethazine 12.5 mg plus ephedrine 25 mg (29%). The only detrimental effect was with scopolamine given orally. It is concluded that the advantages of the transdermal scopolamine, which include minimal side effects and prolonged effectiveness, deserve full exploitation.

Administration, Topical↗