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At least 37 records · Page 2Linked to original sources
PubMed1985

Clostridium septicum panophthalmitis with systemic complications.

A fulminant case of endophthalmitis due to Clostridium septicum is described. The patient presented with spontaneous gas gangrene panophthalmitis, with early visual loss and an air bubble in the anterior chamber. Death ensued, and necropsy revealed changes consistent with severe arterosclerotic cardiovascular disease, a relationship not uncommon in patients with clostridium sepsis. This association as well as the histopathology of the globe are discussed.

Aged↗
PubMedDate not supplied

Tuberculous panophthalmitis.

The case of a one-year-old Nigerian with tuberculous panophthalmitis is reported. He presented initially with a localised episceleral mass which was thought to be retinoblastoma due to rapid spread over the fundus induced by subconjunctival depromedrol. Histological examination of the enucleated eye showed that the lesion was due to tuberculosis. The subsequent favorable response of the ocular and radiological chest lesions to antituberculous therapy was quite remarkable. In contrast, there was an adverse response to radiotherapy which had followed enucleation on the strong suspicion of retinoblastoma. Not unnaturally, ocular tuberculosis was not thought of because of the rarity of ocular involvement with this disease. To our knowledge, this is the first case of its type reported from the African Continent.

Abscess↗
PubMed1979

Bacillus cereus panophthalmitis after intravenous heroin.

Two healthy young black men developed panophthalmitis after intravenous heroin injections. Bacillus cereus, considered to be a relatively noncommon pathogen for man, was found to be the causative agent as it was recovered from the anterior chamber and viterous cavity of both cases. The ocular findings were unilateral in each case, and neither patient had any sistemic involvement from the bacteremia. The onset of visual symptoms varied from 24 to 36 hours after the last intravenous injection with the eye becoming rapidly blind. Photographs of the early fundus lesions included preretinal hypopyon-like lesions and peculiar changes in the blood vasculature. Intracameral gentamicin and steroids did not alter the cause, and treatment was enucleation.

Adult↗
PubMed1991

[Panophthalmitis as a nosocomial infection].

The submitted paper deals with an epidemic of severe postoperative panophthalmitis, its development, course, causes and sequelae incl. epidemiological characteristics. The disease developed in four patients 40 hours after operation of cataract. Despite treatment all four patients developed septicaemia and therefore the affected eyeballs were eviscerated. From smears of the conjunctival sac of the affected patients and from the contents of the eviscerated eyeball Proteus mirabilis and Enterobacter cloaceae were cultivated. The authors draw attention to the epidemiological association with the eye lotion BSS which was used from which Proteus mirabilis and E. coli were cultivated and with the Ringer solution from which Enterobacter cloaceae and Klebsiella pneumoniae were cultivated. An epidemiological analysis of the epidemic was made and provisions were defined to rule out its recurrence.

Cataract Extraction↗
PubMed1990

Acute aseptic panophthalmitis caused by a copper foreign body.

Enucleation was performed on a 10-year-old boy after an eye injury from the explosion of a dynamite cartridge. Amaurosis was noted 48 h after the injury upon admission to our clinic. The clinical picture of panophthalmitis comprised bulbus protrusion with limited movement and hypopion; total retinal detachment was demonstrated by ultrasonography. Intensive pain was present. A histochemical investigation was performed, showing purulent exudation in the anterior chamber, choroid, and retina. Copper stained with rubeanic acid was positive. Electrogravimetrically, the foreign body was found to be 94% copper and approximately 40 mm2 in size.

Child↗
PubMed1987

Endogenous Bacillus cereus panophthalmitis.

Over the past seven years we have treated three cases of drug abusers in whom endogenous Bacillus cereus endophthalmitis rapidly progressed to panophthalmitis. Ocular features of infection with this organism include severe pain, chemosis, proptosis, corneal infiltration and ring abscess, subretinal exudation, retinal hemorrhages, and perivasculitis. The process becomes fulminant in an explosive manner and may be accompanied by fever and leukocytosis. Ophthalmologists should be cognizant of the apparent susceptibility of drug abusers to Bacillus cereus infections and should consider this organism in any severe, rapidly evolving intraocular infectious process.

Adult↗
PubMed1988

Aspergillus panophthalmitis complicating treatment of pterygium.

A 58-year-old woman lost her left eye due to Aspergillus panophthalmitis four months after excision of a pterygium. The patient had received postoperative beta radiation and developed a scleral ulcer in the area of treatment from which no organisms could be cultured on two occasions. Because of the difficulty of diagnosing superficial mycotic infections of the eye, and because the treatment of so-called radiation scleritis may worsen fungal infections, ophthalmologists need to be aware of the potential infectious complications associated with the treatment of pterygia.

Aspergillosis↗
PubMed1985

Lasiodiplodia theobromae panophthalmitis.

Lasiodiplodia theobromae is a rare ocular pathogen. We report a case of panophthalmitis caused by this fungus. The patient was a healthy 62-year-old janitor with no history of ocular trauma in whom keratitis developed. Cultures of corneal scrapings identified the fungus. Despite treatment with appropriate antimycotics the keratitis progressed to infectious scleritis and then spontaneous perforation of the globe, which necessitated enucleation. The ultrasonographic, microbiologic and histologic findings are discussed and the results of in-vitro sensitivity testing presented.

Bacteriological Techniques↗
PubMed1985

Proteinaceous film without macrophages covering lens implant in acute panophthalmitis.

A very well-preserved capsule-like proteinaceous film continuously covering a Copeland lens implant in a late stage of alpha streptococcus panophthalmitis exhibits neutrophils and fibrin as well as massive pus on its outer surface. But no macrophages, fibroblast-like cells, or giant cells are found. The proteinaceous film has resisted the proteolytic actions of the massive pus present on and around the implant.

Acute Disease↗
PubMed1984

Lens implant cyto-pathology in postoperative Proteus panophthalmitis.

The reactive membrane on a posterior chamber lens implant removed from an eye with postoperative proteus mirabilis panophthalmitis was found to be based on a continuous proteinaceous capsule exhibiting only very few fibroblast-like cells. Diffusely arranged neutrophils exhibiting evidence of phagocytosis were attached to a delicate fiber network continuous with the processes of fibroblast-like cells. There was also pus and acellular debris loosely covering the outer surface of this capsule.

Aged↗
PubMed1983

Panophthalmitis and otitis interna in fire-bellied toads.

Microbiologic and histologic studies were made of fire-bellied toads with signs of ocular and central nervous system disease. Providencia alcalifaciens, Citrobacter freundii, Aeromonas hydrophila, and other gram-negative bacilli were isolated from the eyes and multiple tissues of ill toads. The histologic evaluations revealed severe panophthalmitis and otitis interna.

Animals↗
PubMed1980

Panophthalmitis due to Bacillus cereus.

A rapidly progressing panophthalmitis due to Bacillus cereus developed in three patients. Infection was associated with intravenous drug abuse in two patients and was traced to contaminated injection paraphernalia in one. In the third patient, infection was associated with a foreign-body injury to the eye. Anterior chamber aspiration revealed the organism on Gram's stain in one case and isolation of the bacteria in all three. Despite intravenous and intraocular antibiotic therapy, the infection progressed rapidly and resulted in enucleation in all cases. Bacillus cereus isolates were sensitive to clindamycin hydrochloride hydrate and aminoglycosides but resistant to penicillins and cephalosporins.

Adult↗
PubMed1995

Panophthalmitis with acute scleral necrosis after brachytherapy of a malignant melanoma of the ciliary body.

A 52-year-old man who presented with a large ciliochoroidal malignant melanoma was treated by application of a 106Ru plaque. At 8 days after removal of the plaque, severe panophthalmitis with rapidly progressive scleral necrosis at the site of the tumor made enucleation inevitable because of impending perforation of the globe. Microscopic examination revealed an intense inflammatory response and almost complete necrosis of the tumor and overlying sclera. Possible mechanisms for the occurrence of this rare complication are discussed.

Acute Disease↗
PubMed1977

Uveal melanoma presenting as post-traumatic choroidal hemorrhage and panophthalmitis.

A 63-year-old Caucasian man presented with loss of vision in one eye. The loss of vision was considered to be due to a post-traumatic intraocular hemorrhage. He developed panophthalmitis 3 months later and necrosis in a malignant melanoma was diagnosed. The diagnosis of melanoma in patients with blind eyes and opaque ocular media is discussed.

Choroid↗
PubMed1977

Hemophilus orbital cellulitis and panophthalmitis simulating mucormycosis.

A 47-year-old uncontrolled diabetic presented with proptosis, pain, immobility of the globe, and a perforated corneal ulcer. The clinical impression of mucormycosis was erroneous. Hemophilus aegyptius was grown from the orbit, the vitreous and oropharynx. This is believed to be the first report of panophthalmitis due to this organism.

Cellulitis↗
PubMed1987

Tuberculous panophthalmitis associated with drug abuse.

Tuberculous endophthalmitis is a rare condition not described to date in association with intravenous drug abuse. Characteristics such as the lack of proven tuberculous disease in other organs and intense progression towards panophthalmitis make this case all the more interesting. The histopathological diagnosis is based on the identification of acid-alcohol resistant bacilli, and typical granuloma lesions with focal caseosis in stained sections.

Adult↗