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Results for “PASTEURELLA PESTIS”

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PubMed1971

Infectivity and virulence of nonpesticinogenic Pasteurella pestis.

Nonpesticinogenic Pasteurella pestis, which is also negative for coagulase and fibrinolytic activities and therefore referred to as (PI-C-F)(-), was investigated to determine whether greatly reduced and erratic lethal responses observed in mice and guinea pigs might be due to inability of the inoculum to establish infection and multiply in survivors. Immunity of survivors was regarded as an indication of previous infection, and, in the case of guinea pigs infected intradermally, appearance of a local lesion and bubo were also noted. Evidence of infection was obtained in most mice and guinea pigs surviving injection of (PI-C-F)(-) strains G-32 and Dodson, suggesting that the virulence determinant (PI-C-F) is related to lethality rather than to infectivity.

Animals↗
PubMed1966

Effect of diluent and relative humidity on apparent viability of airborne Pasteurella pestis.

Airborne Pasteurella pestis (A-1122) at low humidities [20 to 50% relative humidity (RH)] exhibited exponential decay when either 1% peptone or Heart Infusion Broth (HIB) was used as the diluent in the viable assay system. At higher RH values (65 and 87%), however, the 1% peptone diluent adversely affected the viability assay. In contrast, HIB as diluent was remarkably effective in demonstrating a higher number of viable cells in aerosols held at high RH values. Similarly, with HIB as diluent, aerosols were shown to contain viable cells during 90 min of observation; with 1% peptone, viability was not detectable after 20 min in the airborne state.

Aerosols↗