Tumour production in plants by plant extracts.
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A pharmacological analysis of an aqueous extract of the leaves of Gluta renghas has been carried out. It has been shown that the extract contained a heat-stable, anticholinesterase agent. A heartstimulating substance was also shown to be present in the extract. Intravenous injection of the extract into the anaesthetized cat produced changes of arterial blood pressure, venous pressure and respiration which were reduced or abolished by vagotomy. The leaves contained approximately 0.1 mug./g. of 5-hydroxytryptamine-like activity.
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