SEARCH · PubMed Health

Results for “PSEUDARTHROSIS”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2Linked to original sources

PubMed2005

Posterior transcanal lumbar interbody fusion for septic vertebral fracture pseudarthrosis and sitting imbalance.

STUDY DESIGN: Case report. OBJECTIVE: To describe a new method to treat septic pseudarthrosis of the lumbar spine via a transcanal approach. SUMMARY OF BACKGROUND DATA: Septic pseudarthrosis of the spine after multiple unsuccessful anterior and posterior surgeries for vertebral fracture represents a challenge for spine surgeons. METHODS: Septic pseudarthrosis associated with dorsal fistula developed in a 40-year-old paraplegic man after unsuccessful combined anterior and posterior instrumentation for L3-burst fracture and sagittal sitting imbalance caused by collapsing spine. RESULTS: The instrumentation was removed together with meticulous pseudarthrosis debridement, fistula excision, and intravenous antibiotics plus continuous irrigation. Three months later, the pseudarthrosis area was approached via a posterior transcanal route because of the preceding multiple anterior transperitoneal and retroperitoneal surgeries. Posterior interbody instrumentation and fusion were performed with titanium mesh cages filled with autologous iliac bone graft. Pedicle screw-rod instrumentation was additionally applied to reinforce the interbody fusion and restore lumbar lordosis. Following this operation, the patient was ambulated with a custom made plastic jacket in his wheelchair. The postoperative course was uneventful, and the patient regained his sitting ability progressively. Four months later, the blood count analysis was within normal limits. Radiologically, there was a complete fusion at the level of instrumentation, while the preoperative lost lumbar lordosis was sufficiently restored. The patient was reemployed 6 months after surgery in his previous work in a sitting position, and, during the last observation 4 years later, he had normal labor analysis and lumbar lordosis. CONCLUSION: This extremely rare case focuses on the use of the transcanal approach to treat adequately lumbar septic pseudarthrosis and restore lumbar lordosis in definitively paraplegic patients in whom no anterior approach can be used.

Adult↗

PubMed2005

NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis.

Neurofibromatosis type 1 (NF1) is an inherited disease with an incidence of about 1:3000 worldwide. Approximately half of all patients with NF1 present osseous manifestations, which can vary from mild to severely debilitating changes such as congenital pseudarthrosis. In the present study, fracture healing of mouse tibia was followed and specimens were collected 5, 9, 14, and 22 days postoperatively. Experimental pseudarthrosis of rat was followed up to 15 weeks postoperatively. In situ hybridization and immunohistochemistry were used to demonstrate expression of NF1 tumor suppressor and phosphorylated p44/42 mitogen-activated protein kinase (MAPK), an indicator of the Ras-MAPK pathway. The results showed that ossified callus was formed in mouse fracture 22 days after the operation. The final outcome of rat pseudarthrosis was detected 9 weeks after the operation, presenting abundant cartilaginous callus at the pseudarthrosis. NF1 gene expression was noted in the maturing and in the hypertrophic cartilages during normal mouse fracture healing, and in rat pseudarthrosis. Phosphorylated p44/42 MAPK was detected in a subpopulation of the hypertrophic chondrocytes in both models. Furthermore, positive labeling for NF1 mRNA and protein was detected in endothelium in both the pseudarthrosis and in the fracture. In conclusion, NF1 gene expression and function are needed for normal fracture healing, possibly restraining excessive Ras-MAPK pathway activation.

Animals↗

PubMed1989

Fractures of the dens and risk of pseudarthrosis.

This study deals with 49 fractures of the dens treated at the Orthopedic Department of Athens University during the past 17 years. These fractures represent 14.2% of all cervical fractures treated during the same period at our department. Forty-one cases have been reviewed and analyzed, the average follow-up time being 10 years (1-16). Pseudarthrosis was found to be present in seven cases (17%), and its relationship to different factors was examined. The type of fracture and particularly the direction of the fracture line were found to be major factors leading to pseudarthrosis. Many other factors, such as displacement, traction, the stability obtained, the presence of associated injuries, and the time elapsed till treatment was started, as well as the age of the patients, seem to play--alone or in combination--important roles in the development of pseudarthrosis. These factors have been classified according to their importance and graded. With a total of 10 points or more a dens fracture is characterized as a fracture "at risk of pseudarthrosis", i.e., a fracture with a higher possibility of developing a pseudarthrosis. This knowledge may contribute to proper and earlier management of such an injury.

Adolescent↗

PubMed1999

[The biological reaction in atrophic and hypertrophic pseudarthrosis of diaphysis of long bone. Causes and forms of appearance].

The grading of long-tubular-bone pseudarthrosis depends on the biological reaction or lack of reaction in pseudarthrosis or non-unions. Hypertrophic and oligotrophic pseudarthrosis belongs to biologically reacting non-unions, whereas non-reacting non-unions are necrotic pseudarthrosis and defective non-unions with partial decline or complete destruction of cortical substance. Pseudarthrosis is a serious disturbance or disorder within the regulation cycle in fracture healing, which consists of osteoregeneration, osteovascularization and stabilization. The causes and underlying reasons for disturbance of this regulation cycle are primarily massive destruction of the biological and functional very important unity of periost, cortical substance and medullary space. This can occur from trauma, but it happens more often from surgical procedures that do not take the biological principles of bone-healing into account. Surgical strategies and interventions that respect the importance of periosteal tissue, cortical tissue and medullary space do fill the biological principles of fracture-healing and fracture union.

Animals↗

PubMed2002

[High energy extracorporeal shockwave therapy (ESWT) in pseudarthrosis].

The gold standard for treatment of pseudarthrosis is operation with osteosynthesis and grafting. More than 10 years ago, extracorporeal shock wave therapy (ESWT) was additionally introduced as a noninvasive and low-risk treatment for pseudarthrosis. The aim of our prospective study was to analyze the treatment effect in a homogeneous group of patients and to develop prognostic factors. Forty-three consecutive patients were included in this study. All patients had been operated on for trauma or undergone selective osteotomy and had developed pseudarthrosis that persisted for 9 months. All patients received high-energy ESWT (0.6 mJ/mm2) with 3000 impulses (Siemens Osteostar) in one session under regional anesthesia. To differentiate active from inactive pseudarthrosis, a bone scintigraphy was compulsory. Clinical and radiological follow-ups were done at 4-week intervals starting 8 weeks after ESWT for 9 months. Cortical bridging was found in 31 of 43 (72.1%) pseudarthroses at 4.0 +/- 0.6 months after ESWT. Of 31 (80.6%) successfully treated patients, 25 had a positive scintigraphy compared to 4 of 12 (33.3%) treatment failures. Of 35 (82.9%) patients with a positive bone scintigraphy, 29 had bony healing compared to 2 of 8 (25%) patients with a negative bone scintigraphy. Six of these eight patients smoked more than 20 cigarettes a day. ESWT is still a clinically experimental treatment method. The absence of complications justifies its use for pseudarthrosis treatment. Further controlled studies are mandatory.

Adolescent↗

PubMed2004

Congenital (infantile) pseudarthrosis of the fibula associated with osteofibrous dysplasia.

We describe a recently noted association of congenital (infantile) pseudarthrosis of the lower leg with osteofibrous dysplasia. The patient was a 2-year-old boy who presented with a deformed left ankle joint and three cutaneous cafe-au-lait spots. Radiography demonstrated pseudarthrosis of the left distal fibula and a round lucent lesion adjacent to the proximal part of the pseudarthrosis. Histologically, the surgically removed fibula with pseudarthrosis showed a fibromatosis-like fibrovascular proliferation and nonspecific reparative changes. The focal lucent area demonstrated a fibro-osseous lesion, which was histologically identical to osteofibrous dysplasia. This case provides further evidence that osteofibrous dysplasia may be associated with congenital (infantile) pseudarthrosis of the lower leg.

Child, Preschool↗

PubMed2004

Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective long-term study comparing fusion and pseudarthrosis.

STUDY DESIGN: A prospective, randomized study on patients who underwent posterior lumbar decompression with bilateral posterolateral arthrodesis. OBJECTIVE: To determine the long-term influence of pseudarthrosis on the clinical outcome of patients with degenerative spondylolisthesis and spinal stenosis. SUMMARY OF BACKGROUND DATA: Spinal decompression and posterolateral arthrodesis have been shown to be beneficial in the surgical treatment of symptomatic spinal stenosis with concurrent spondylolisthesis. METHODS: Forty-seven patients with single-level symptomatic spinal stenosis and spondylolisthesis were prospectively studied. Patients were treated with posterior decompression and bilateral posterolateral arthrodesis with autogenous bone graft. Radiographic evaluation was used to determine if fusion or pseudarthrosis was present. The solid fusion and pseudarthrosis groups were analyzed clinically, roentgenographically, and with a validated self-administered spinal stenosis questionnaire. RESULTS: Forty-seven patients were available for review at a range of follow-up from 5 to 14 years. Average follow-up was 7 years 8 months. Clinical outcome was excellent to good in 86% of patients with a solid arthrodesis and in 56% of patients with a pseudarthrosis (P = 0.01). Significant differences in residual back and lower limb pain was discovered between the two groups using a scale ranging from 0 (no pain) to 5 (severe pain). Preoperative back and lower limb pain scores were statistically similar between the two groups. The solid fusion group performed significantly better in the symptom severity and physical function categories on the self-administered questionnaire. The two groups had similar results in the patient satisfaction category of this questionnaire. CONCLUSIONS: In patients undergoing single-level decompression and posterolateral arthrodesis for spinal stenosis and concurrent spondylolisthesis, a solid fusion improves long-term clinical results. Benefits of a successful arthrodesis over pseudarthrosis were demonstrated with respect to back and lower limb symptomatology compared with prior shorter-term studies, which indicated no significant difference in clinical outcome between the two groups.

Aged↗

PubMedDate not supplied

Forearm pseudarthrosis--neurofibromatosis: case report.

A 3 1/2-year-old white girl with neurofibromatosis sustained left radius and ulna fractures. The radius was sclerotic with no medullary canal at the fracture site, and the ulna was hypoplastic distal to the fracture. The fractures failed to unite when immobilized in a long arm plaster cast for 5 months and pseudarthrosis developed. Three subsequent operative attempts to obtain union of the pseudarthrosis by means of internal fixation and bone grafting over the next 30 months were also unsuccessful, and the pseudarthrosis persisted. The forearm was supported in a custom molded leather brace until the child was 13 1/2 years old and had reached skeletal maturity. Osseous union was then operatively obtained using dual onlay tibial cortical and cancellous bone grafts. There has been no recurrence of the pseudarthrosis 3 years and 2 months after bone grafting. The author recommends postponing surgical attempts to achieve union of the forearm bone pseudarthrosis associated with neurofibromatosis until the patient reaches skeletal maturity.

Bone Neoplasms↗

PubMed2003

[Arterial complications of thoracic outlet syndrome and pseudarthrosis of the clavicle: three patients].

During a 3-year period, three patients developed arterial complications related to congenital or post-traumatic old pseudarthrosis of the clavicle. Arterial complications of pseudarthrosis of the clavicle presenting as a thoracic outlet syndrome are very rare. Symptoms are variable and occur late. Without treatment, the prognosis is poor with spontaneous development of gangrene. Arterial morphology investigations should be undertaken in patients with pseudarthrosis of the clavicle or isolated arterial symptoms involving the upper limb whose radial pulse disappears during postural tests. Duplex Doppler of the subclavian artery is an excellent screening exam but selective arteriography is the gold standard. It shows proximal arterial lesions (embolytic stenosis of the subclavian artery with post-stenotic dilatation), as well as distal embolic complications. Both static and postural tests must be performed to unmask subclavian restriction by the clavicle, proving its causal effect in the arterial complications. There are four clinical varieties: chronic thrombosis of the subclavian artery, distal arterial micro emboli, acute thrombosis of proximal arteries of the upper limb, and subclavian aneurysm. These lesions are thought to be due to chronic constriction and repeated arterial microtrauma. Congenital or post-traumatic pseudarthrosis, hypertrophic callus, arterial restriction by a screw in a clavicular plate, usually explain the arterial lesions. Bone tumors and Paget's disease are potential but exceptional clavicular etiologies. Surgical treatment is always necessary. Clavicular resection is usually needed in case of pseudarthrosis; there is no functional handicap. Plate fixation and autologous grafting, or open reduction and internal fixation are other valid surgical treatments; The embolytic lesions must be treated to prevent recurrence of distal embolization: graft resection and thromboendarteriectomy have been described. Neurological and venous decompression may be associated at the same time. Complementary treatment can be associated: distal bypass, cervicothoracic sympathectomy, in situ thrombolysis or thrombectomy. Endovascular treatment is not indicated. Optimal treatment of clavicular fractures is required to prevent the development of thoracic outlet syndrome.

Aged↗

PubMed1985

Pseudarthrosis after spinal fusion for scoliosis. A comparison of autogeneic and allogeneic bone grafts.

This study was undertaken to compare the incidence of pseudarthrosis in fusions supplemented with autogeneic and frozen allogeneic grafts. The records of 208 patients with adolescent idiopathic scoliosis who were treated by posterior fusion and Harrington instrumentation were studied. The fusion was supplemented by an autogeneic iliac bone graft in 114 patients and by an allogeneic bank bone graft in 94 patients. The fusion mass was explored in all patients with suspected pseudarthrosis; therefore, all pseudarthroses reported in this series were proved by surgical exploration. Pseudarthrosis developed in five patients (4.4%) receiving an autogeneic graft and in five patients (5.3%) receiving an allogeneic graft. The incidence of pseudarthrosis was not significantly different at the 95% level of certainty. Average blood loss and operative time were determined for all patients. The decreases in average blood loss and operative time in those patients receiving allogeneic grafts were significant (p less than .01). Thus, based on the incidence of pseudarthrosis, allogeneic frozen bank-stored bone is an attractive alternative to autogeneic iliac bone for fusion supplementation in the treatment of scoliosis. Total operative time and blood loss can be decreased, and possible complications associated with a donor site can be avoided.

Adolescent↗

PubMed1994

Congenital pseudarthrosis of the tibia in adults treated by a free vascularized iliac crest graft.

Congenital pseudarthrosis of the tibia is a rare condition. It usually presents during early childhood, at which time the surgeon is faced with numerous challenges including difficulties in achieving union and preventing refractures and recurrences. Patients frequently end up with a severe deformity or an amputation. When an adult patient presents with previously untreated congenital pseudarthrosis of the tibia, the surgeon is faced with the additional problems of a long-standing soft tissue contracture and disuse atrophy of the limb. Two patients with congenital pseudarthrosis of the tibia were treated by free vascularized iliac crest graft. Soft tissue deformity was corrected using an external fixation device. The patients were not freely ambulatory before surgery. Union across the pseudarthrosis was achieved in both patients with a double-staged operation, within a short period of time. A functional stable painless limb with good knee and ankle motion has allowed both patients to resume bipedal gait and achieve a successful rehabilitation.

Adult↗

PubMed1984

Light- and electron-microscopic studies in congenital pseudarthrosis.

This study presents the results of light- and electron-microscopic and enzyme histochemical investigations in ten cases of congenital pseudarthrosis of the lower limb. At the time of surgery, six of the ten patients had not been operated on previously. The characteristic histological feature of the "sclerotic type" of congenital pseudarthrosis was a marked fibromatous reaction consisting of cellular connective tissue. The constituent cells were arranged in bundles and had elongated nuclei. The number of nuclei per visual field was considerably higher in pathological specimens than in specimens from the uninvolved leg. In places, the histological appearance resembled somewhat that of palmar fibromatosis (Dupuytren's disease). Destruction and absorption of bone were always found. Electron-microscopic analysis showed that a large number of the cells represented myofibroblasts. These findings were supported by the positive reaction of the cells for the enzyme diaminopeptidase IV, a marker enzyme for myofibroblasts [30]. As yet it is not possible to decide whether the constriction of the pseudarthritic bone is caused by a thickened myofibroblast-containing periosteum [40] or by the aggressive osteolytic component of the fibromatosis [12, 19, 41]. Furthermore, the relationship of congenital pseudarthrosis to fibrous dysplasia of bone is still unknown. Obviously, there are histological similarities between the two diseases, including the presence of osteolytic fibrous tissue in the medullary cavity and C-shaped bone trabeculae. However, the pattern of bone involvement and prognosis are different. Irrespective of the type of congenital pseudarthrosis, focal angiomatous hyperplasia was noted in some cases. This proliferation of blood vessels is most likely a reactive change.(ABSTRACT TRUNCATED AT 250 WORDS)

Bone and Bones↗

PubMed2002

[Anterograde intramedullary tibio-talo calcaneus arthrodesis (aIMTCA) with spongiosaplasty in pseudarthrosis].

Pseudarthrosis occur in 65% of all ankle joint arthrodesis. From the therapeutical point of view we make a distinction between vital (hypertrophic) and avital (hypotrophic) respectively stable and instable pseudarthrosis. The hypotrophic forms demand an additional cancellous or bone grafting. Especially instable pseudarthrosis have to be treated with a biological osteosynthesis. In the hindfoot the so called compression arthrodesis made one's way. But there is still a discussion about the best method, intern or extern fixation. We report about a case of hypotrophic pseudarthrosis with a mal-position occurring after an ankle joint arthrodesis with a Charnley-Fixateur. A fusion of the ankle joint could be carried out with a proximal respectively anterograde intramedullary nail and allogene cancellous graft.

Ankle Joint↗

PubMed1996

[Treatment principles in aseptic pseudarthrosis].

Aseptic pseudarthrosis may occur after all kinds of traumatology treatment. Following conservative treatment, incomplete immobilisation or an unattached bone fragment can be causal. After plate osteosynthesis the biomechanical principles are not efficient or the circulatory damage delays healing. There are two broad types of pseudarthrosis: vascular and nonvascular. The extent of vascularisation can be demonstrated by bone scintigraphy as well as X-ray. The treatment of vascular nonunions is very common. Mechanical stability is required, therefore a new osteosynthesis is desirable. Osteoporosis caused by inactivity and dislocation increases the rate of complications. Much more difficult problems are encountered in treatment of unreactive and avital pseudarthrosis, particularly in cases with a defect of bone substance. These defects can be treated with a segment transfer and a fibula-to-tibia operation. Extracorporal lithotripsy has been established as a new method in treatment of active and vascular nonunions. Former osteosynthesis is not a contraindication. Stability and immobilisation are necessary. Treatment in the low-frequency magnetic field shows no effect. Correct biomechanical and biological osteosynthesis with proper attention paid to location, quality of bone and asepsis can avoid the development of a pseudarthrosis.

Adolescent↗

PubMedDate not supplied

Prospective clinical outcomes of revision fusion surgery in patients with pseudarthrosis after posterior lumbar interbody fusions using stand-alone metallic cages.

BACKGROUND CONTEXT: Posterior lumbar interbody fusion (PLIF) is a popular method of arthrodesis for surgical treatment of instabilities and degenerative conditions of the spine. With the introduction of threaded titanium cage devices, surgeons began performing PLIF procedures using these cages as stand-alone devices. Complications have been reported, however, including pseudarthrosis with persistent pain. Outcomes after revision surgical treatment for these patients with failed PLIF are not known. PURPOSE: To prospectively evaluate clinical outcomes of revision fusion surgery in patients who previously underwent posterior lumbar interbody fusion with stand-alone metallic cages resulting in pseudarthrosis. STUDY DESIGN/SETTING: Prospective case series. METHODS: Nineteen patients referred to the senior author were evaluated and diagnosed with pseudoarthrosis having previously undergone a PLIF procedure with stand-alone metallic cages. History, physical exam, and imaging studies were performed preoperatively and postoperatively. All underwent revision posterolateral fusion with iliac crest graft and pedicle screw instrumentation. Patient demographics, SF-36, and Oswestry Disability Index (ODI) data were collected prior to surgery and two years postoperatively. RESULTS: Patients undergoing revision fusion surgery were found to have had extensive facetectomies and pseudarthrosis intraoperatively. Outcomes data was collected on eighteen of nineteen patients (95%). Mean clinical follow up was 3.2 years (range 2.5-3.5 years). Seventeen patients (94%) achieved a solid fusion. Improvement was noted in seven of eight SF-36 sub-categories, but was significant only in two (Physical Function and Role Emotional). There was no significant difference in ODI scores. CONCLUSIONS: Pseudarthrosis should be considered in the differential diagnosis if severe symptoms persist in patients who undergo PLIF with stand-alone metallic cages. Successful revision fusion did not always correlate with improved clinical outcomes in these challenging patients undergoing further surgery. Performing PLIF using stand-alone metallic cages, especially after total resection of the facet joints, is not advocated unless supplemental instrumentation is utilized.

Adult↗

PubMed2004

[Management of painful pseudarthrosis of the carpal scaphoid bone with closed wedge osteotomy of the distal radius: a prospective study with long-term follow-up].

PURPOSE OF THE STUDY: We propose a different management scheme for painful post-traumatic osteoarthritis of the wrist resulting from pseudarthrosis of the carpal scaphoid bone. We report a prospective series with a maximum follow-up of 16 years. MATERIAL AND METHODS: From 1973 to 1990, we performed 100 first-intention wedge osteotomies of the distal radius in patients with painful pseudarthrosis of the carpal scaphoid bone. Inclusion criteria were painful wrists with established pseudarthrosis. The operation consisted in the removal of a small lateral wedge (base f 0.5 cm) without affecting the length of the radius nor the function of the distal radio-ulnar joint. Twenty patients were lost to follow-up and follow-up was less than two years for two. The present series corresponds to 77 patients (all male manual laborers) followed for at least two years. Mean follow-up was 4 years (range 216 years). To evaluate outcome, we developed a devoted scoring system, the Scaphoid Pseudarthosis Hand Score, (SPHS, max 60 points) with items for pain, range of motion, grasping strength, work capacity, wrist function and post-traumatic arthritis. RESULTS: At last follow-up, the SPHS was 45.66 points versus 19.98 before surgery. The pain score was 8.51 versus 3.19: 67 patients (86%) were pain free or experienced mild pain for heavy work. Bone fusion or fibrous union was observed in 49 patients (64%) who were free of post-traumatic osteoarthritis; some improvement of which was observed in 11 other patients (14%) with less sclerotic bone. All patients but two resumed their occupational activities. DISCUSSION: Wedge osteotomy relieves pain and improves hand function by reducing the pressure applied to the radial and scaphoid joint surfaces. It acts positively in the event of post-traumatic arthritis, altering the dynamics of the wrist and producing the beneficial effects of styloidectomy. Although it was not the target, sound union of the pseudarthrosis observed in 25 patients at last follow-up was attributed to the applied treatment.

Adult↗

PubMed2001

Reoperation rates for acute graft extrusion and pseudarthrosis after one-level anterior corpectomy and fusion with and without plate instrumentation: etiology and corrective management.

BACKGROUND: Reoperation rates after one-level anterior cervical corpectomy with fusion (ACF) performed without and with plates need further evaluation. METHODS: Reoperation rates for graft extrusion and symptomatic pseudarthrosis were analyzed following 48 nonplated (1989-1996) and 35 plated (1997-2000) one-level ACF. Preoperatively, patients typically exhibited mild/moderate myelopathy attributed to spondylostenosis and ossification of the posterior longitudinal ligament (OPLL). Thirty-five ACF were performed with plates: 3 Orion, 12 Atlantis, and 20 ABC Aesculap plates. Fusion was documented on both dynamic X-rays and 2- or 3-dimensional CT studies 3 and 6 months postoperatively, or until fusion occurred. Follow-up averaged 82 months for the nonplated patients, and 21 months for the plated patients. RESULTS: Out of 48 nonplated patients, 3 developed immediate graft extrusions within 24 hours of surgery requiring graft replacement. Another 2 exhibited symptomatic pseudarthrosis 6 months postoperatively, and required secondary posterior wiring with fusion (PWF). In comparison, 1 of the 35 patients with plated one-level ACF developed plate displacement 6 weeks postoperatively, while 3 exhibited symptomatic pseudarthrosis 6 months after surgery, and required secondary posterior wiring and fusion (PWF). CONCLUSIONS: Comparison of one-level ACF performed with and without plates showed that plating did not appear to reduce pseudarthrosis or graft extrusion rates.

Adult↗

PubMed1995

Familial congenital pseudarthrosis of the ulna.

A mother and daughter, both presented with congenital pseudarthrosis of the ulna due to neurofibromatosis. The daughter is one of identical twins, the second twin not having a pseudarthrosis. The mother's uncle also had pseudarthrosis of the tibia. This suggests a complex variable genetic inheritance pattern for pseudarthrosis in neurofibromatosis. Despite having had no treatment, the mother had minimal symptoms, minimal deformity, and no radial head dislocation.

Child, Preschool↗