SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Recent studies are reviewed that suggest that preschool and young grade-school children often have incomplete or distorted impressions of social portrayals on television. It is suggested that cognitive-processing factors in understanding television dramas may put these younger viewers at special risk for deleterious effects of television viewing.
Some children with cerebral palsy attend the ten-form general polytechnical school. To this end, several prerequisites have to be fulfilled and other essential arrangements to be developed in cooperation with specially trained teachers. The learning conditions have to be fitted to the improving abilities of children during the educational process. Factors of influence and cooperation modes are discussed.
The study tries to demonstrate, that the combination of the actualgenetic method (Sander, Froehlich), and the VEP, allows a systematic and differentiated analysis of the psychophysiological process of visual thinking. A student group was compared with mental retardates in VEP and EOG, watching actualgenetically manipulated picture series. Phasic EEG-changes are significantly related to the identification process. Most sensitive are amplitude changes about 120 to 270 msec. The mental retardates had significant VEP changes 180--270 msec, the students 128--192 msec after picture presentation. The process factor analysis (Pawlik) elaborated an illumination factor and two factors being labelled general reaction set. VEP averaging over the persons revealed different attention and/or discrimination behavior for the student group and the mental retardates, identifying the picture objects.
The literature on the syndromes associated with the styloid process is reviewed. The anatomy and embryology of the styloid apparatus are then discussed in relation to the development of these conditions; attention is drawn to the significance of elongation of the process. Eighty styloids measured at post-mortem examination enabled a mean length to be determined as well as a range of normals. The possible aetiological factors are then listed. Four cases of elongated styloid process are described, three treated by excision via an external approach and the fourth presenting as an asymptomatic lump in the neck, not requiring treatment. The authors' preference for the external approach is explained.
Experiments were conducted on rat jejunum pouches turned inside-out. On addition of blood plasma containing the natriuretic factor there was a reverse relationship between the natriuretic factor concentration and the processes of absorption in the jejunum. No such effect was noted under the effect of aldosterone and vasopressin.
21 young female and 15 young male patients with cerebrovascular insults were examined for risk factors. 14 of the 15 male patients showed clear cut risk factors: obesity, diabetes, hyperlipidemia, arterial hypertension, smoking, thromboses, vitium cordis. 20 of the 21 female patients took oral contraceptives. 60% of the female patients with angiographically confirmed stenoses and occlusion did not show any other risk factor. These results support the hypothesis that oral contraceptives are in themselves a risk factor.
Explore the source record for details and available documents.
Intrinsic lamprey factor XIII cross-links the gamma chain of lamprey fibrin (50,000 daltons) to the gamma-dimer (100,000 daltons). The alpha-chain (110,000 daltons) is cross-linked very slowly to alpha-dimer (210,000 daltons) and alpha-trimer (330,000 daltons). In contrast, human factor XIII, when added in combination with intrinsic lamprey factor XIII, cross-links the alpha-chain of lamprey fibrin to a high molecular weight polymer, and any remaining gamma-chain is also cross-linked to a polymer. However, the gamma-chain that has previously cross-linked to the gamma-dimer by the intrinsic lamprey factor XIII remains as a gamma-dimer. Factor XIII-free lamprey fibrin cross-links all its subunits (alpha, beta, gamma) to high molecular weight polymers when human factor XIII is added. In contrast to human and bovine fibrin where alpha-chain cross-linking in the process of blood coagulation commences when all of the gamma-chain has cross-linked, the lamprey alpha-chain will begin to cross-link when approximately half of the gamma-chain has cross-linked to the gamma-dimer.
Explore the source record for details and available documents.
A factor having activity similar to that described in other systems for the eukaryotic elongation factor eEF-Ts was isolated from the heavy, aggregate form of eEF-TH (formally named EF-1H). This protein has a molecular weight of 52000 under native conditions and of 25500 under denaturing conditions. It has been shown to stimulate eEF-Tu-dependent aminoacyl-tRNA binding to ribosomes and therefore eEF-Tu/eEF-G-dependent polyphenylalanine synthesis by ribosomes and was found to stimulate GDP-GTP exchange in eEF-Tu . GDP complexes. In the course of this work, it was also demonstrated that the removal of deacylated tRNA from the ribosome is a GTP-dependent process. This report, therefore, adds further support to the concept that a third elongation factor, eEF-Ts, may be common to all systems in the eukaryotic domain.
Animal experiments were carried out to study the effects of a feeding regimen and diet composition on the intensity of post-decompression bubble formation as well as to establish a correlation between this process and previous decompression, increased and decreased muscle work, and physico-chemical and morphological blood parameters. There was a correlation between the rate of bubble formation during decompression and the above factors.
Explore the source record for details and available documents.
A system of translation of matrix-bound poly(U) by purified Escherichia coli ribosomes was used to obtain pre-translocation state ribosomes in columns and then to induce translocation under controlled conditions by passing the elongation factor G (EF-G) with the non-cleavable GTP analog (guanylyl-methylene diphosphonate). It has been shown that translocation in the ribosome, checked by the release of deacylated tRNA, as well as by the puromycin reaction, is induced by the attachment of EF-G (with the non-cleavable GTP analog) to the ribosome and not by its detachment. In accordance with this, the ionic conditions under which the affinity of EF-G with the GTP analog to the ribosome is increased (NH4Cl instead of KCl, a lowered ionic strength) have been also found to be more effective for translocation. On the other hand, it has been shown that the detachment (removal) of EF-G is a strict pre-requisite for the appearance of competence to bind the next aminoacyl-tRNA, and thus for a continuation of the elongation cycle. A conclusion is made that the mechanical shifts of products and substrates, such as peptidyl-tRNA and deacylated tRNA, within the ribosome in the process of translocation are promoted only by the affinity of EF-G to the ribosome and does not depend on the cleavage of GTP. On the basis of the results obtained, the following sequence of events is deduced for the process of EF-G-promoted translocation: 1) interaction of EF-G.GTP with the pre-translocative ribosome, 2) translocation displacements of products and substrates, including the release of deacylated tRNA (probably conjugated with the shift of mRNA), 3) GTP hydrolysis, 4) release of EF-G and GTP from the post-translocated ribosome.
The temperature differences obtaining in the subcutaneous tissues directly below the zone exposed to ultrasonic irradiation, the liver an the myocardium of white rats were measured during and after ultrasonic treatment. The only rise in temperature was observed in the tissues located below the field of ultrasonic irradiation after the second minute. The temperature drop in each of the three types of tissue examined is a characteristic feature. This paradoxical effect produced by ultrasonic intensities of 0.2, 0.6, 1.0, and 1.6 watt/cm-2, which has not as yet been described in the literature, may be explained by the control mechanisms keeping the internal body temperature relatively constant and, in particular, by those mechanisms of temperature regulation which are controlled by the biogenic amines.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
LRF and one of its highly potent analogs, [D-Trp6-Pro9-NEt]LRF (A), were tested for their effects on pregnancy. Daily doses of A prevented implantation and/or caused resorption of implanted blastocysts in mated female rats. This effect was dose related and was most evident when given in regimens including days 5-7 or days 9-10 or pregnancy. LRF also has antigonadal effects, but at much higher doses than A. The use of corn oil vs. 0.1% gelatin-saline improved the effectiveness of low doses of A. Termination of pregnancy in A- or LRF-treated rats is most probably due to the markedly diminished progesterone secretion, which could result from the secretion of biologically inactive gonadotropins, reduced pituitary responsiveness to endogenous LRF, or down-regulation of gonadal receptors for LH.