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Results for “Puerperal Infection”

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At least 37 records · Page 2Linked to original sources
PubMed1976

Puerperal infection in the antibiotic era.

Developments in etiology and treatment of puerperal infection in the last 20 years are reviewed. Emphasis is placed upon predisposing factors, microbiology and antibiotics, unusual sources of severe infection, special complications, and prophylactic antibiotics.

Anti-Bacterial Agents↗
PubMed1993

[Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk].

The aims of this study were, to determine the pharmacokinetic parameters of clarithromycin and to study the passage of the drug into breast milk. Twelve patients (age 24 to 38; weight 44 to 83 kg), suffering from puerperal infections, were treated orally with 250 mg clarithromycin b.i.d. for 6 days. Samples of blood and breast milk were taken at timed intervals. The specimens were assayed for clarithromycin and its active metabolite 14-hydroxy-clarithromycin by HPLC and electrochemical detection. Serum concentrations of clarithromycin in the investigated patients were higher than those reported in healthy volunteers. The mean peak concentrations of clarithromycin and 14-hydroxy-clarithromycin in breast milk were about 25%, and 75% respectively of the corresponding serum concentrations. All patients recovered within 2 to 4 days and no drug-associated side effects (eg. gastrointestinal) were noted. Clarithromycin appears to be an appropriate antibiotic for the treatment of puerperal infections and (because of its considerable concentrations in breast milk) for puerperal mastitis as well.

Administration, Oral↗
PubMed1978

Puerperal infection due to group A beta hemolytic streptococcus.

A cluster of 5 patients with puerperal infection due to group A beta hemolytic streptococcus (GABHS) is described. The most striking clinical signs included the early onset of uterine tenderness followed by an abrupt temperature elevation to greater than or equal to 102 F. At the time of uterine tenderness (Day 2, postpartum), 4 of 5 patients had gram-stained lochial smears showing a predominance of gram-positive cocci. The cluster of cases occurred with no source of the infection identified after 365 culture attempts. Therapy was rapidly successful with intravenous penicillin.

Cross Infection↗
PubMed1981

Group B beta-hemolytic streptococci and puerperal infections.

Group B beta-hemolytic streptococci as a major cause of puerperal infection in 40 patients is described. Unique features of this bacterial infection are the development of an average peak oral temperature within 12 hours of delivery, tachycardia, distended abdomen, and endomyometritis or endomyoparametritis. Bacteremia occurred in 35% of these patients.

Adolescent↗
PubMed1980

Clinical risk factors for puerperal infection.

Recent studies have identified clinical features that are major risk factors for puerperal infection. Patients of low socioeconomic status undergoing cesarean section who have had prolonged labor and rupture of membranes (ROM) incur a 40 to 85% risk of endometritis. Infection occurs generally in less than 10% of women undergoing vaginal delivery, even when complicated by prolonged ROM, and often in considerably fewer cases. Other features such as internal monitoring, obesity, anemia, and general anesthesia have not been consistent determinants in recent studies.

Cesarean Section↗
PubMed2006

Infective puerperal endocarditis caused by Escherichia coli.

Presentation is made of a rare case of infective puerperal endocarditis involving the native mitral valve in a young puerpera after cesarean section, without a history of pre-existing heart disease, inflammation focus or intravenous drug abuse.

Adolescent↗
PubMed1992

Life-threatening puerperal infection due to group A streptococci.

We describe two patients with life-threatening puerperal infection due to group A beta-hemolytic streptococcus. Each patient had bacteremia, shock, and multi-organ involvement. Both cases were compatible with a recently described streptococcal toxic shock-like illness. Both women failed to improve despite vigorous medical and antibiotic therapies, and each required hysterectomy. Obstetricians should be alert to the importance of early diagnosis and treatment of this potentially lethal infection.

Adult↗