PubMed1996
The authors have reviewed the literature particularly of the last decade, about surgical indications and timing in chronic ulcerative proctocolitis, also regarding the difficulties and the hazards the surgeon has to face depending on which type of chronic disease is considered. The various solutions for intestinal transit restoration have been reviewed, especially after the indications for terminal and continent ileostomy and for ileo-rectal anastomosis have been put aside, and total proctocolectomy with mucosectomy was advocated, with a special concern for assets and drawbacks of every type of ileal pouch. It is herein discussed the difference between the attitudes towards chronic active and recurrent ulcerative proctocolitis. The active form can't be cured with steroids and shows a greater risk of malignant transformation after 10-15 years of illness, insofar most cases (82%) in the long run need operation with this form that just often permits a one-stage surgery with mucosectomy, though. The commoner recurrent form is quite sensitive to steroids until these prove to be ineffective and surgery becomes mandatory (28% of cases). A two or three-stage surgery is advocated in this form with conservation of the rectum (mucosal fistula) as long as the acute phase is present, permitting only after its remission a restorative procedure with mucosectomy, which would be likely to be jeopardizing during the acute phase. The many designs of ileal reservoir do not differ indeed between each other as much in compliance as in maximum tolerable volume. The quadruple loop reservoir affords a volume approaching highly the original rectal volume, with better compliance and lesser frequency of bowel evacuations compared to other pouch designs. Some authors maintain that the functional outcome is independent of the reservoir shape. The anal continence basically depends upon the integrity of the internal sphincter, on the conservation of the anal inhibitory reflex and on the resting pressure. Muscular cuff is also mentioned with reference to anal function. Circular staplers have been employed for pouch-anal anastomosis 1-2 cm above the dentate line without mucosectomy. The stapled pouch-anal anastomosis entails a damage to the internal sphincter by some authors on the contrary a better sphincter function by others, compared to hand-sewn anastomosis with mucosectomy. Trials are needed to compare the risk of rectocolitis recurrence or malignancy after hand-sewn pouch-anal anastomosis with mucosectomy and after stapled anastomosis without mucosectomy. Postoperative complications are also herein discussed, with a special regard to pouchitis and its various aetiologic factors in early and late postoperative course.