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Spontaneous tumors and common diseases in two colonies of Syrian hamsters. II. Respiratory tract and digestive system.

Spontaneous respiratory tract neoplasms in Syrian hamsters occurred in almost equal frequencies in two colonies: 3% in the Eppley Colony (EC) and 3.6% in the Hannover Colony (HC). Neoplasms were in the nasal cavity, trachea, and lungs, and most were benign; however, 2 adenocarcinomas of the nasal cavity (EC) and 1 adenocarcinoma of the larynx (HC) were found. The incidence of digestive tract tumors showed a more marked difference than that of the respiratory tract: 7% in the EC and 23% in the HC. Digestive tract tumors accounted for 15 and 41% of all tumors in the EC and HC, respectively. All EC digestive tract neoplasms were benign and occurred mostly in males; 19 (83%) were forestomach papillomas and the remaining 4 )17%) were liver hemangioendotheliomas (2) and pancreatic duct adenomas (2). In the HC, almost 50% of the digestive tract neoplasms were malignant and most frequent in females. These tumours include 19(42%) intestinal adenocarcinomas, 18(40%) liver neoplasms (hemangioendotheliomas, cholangiomas, cholangiocarcinomas), 5 (13%) forestomach papillomas, and 2 (4%) gallbladder polyps. The morphology of these neoplasms was reported.

Adenocarcinoma↗

[Statistics and prehospital diagnosis of malignant neoplasms of upper respiratory tract in Russia].

In 1990 in Russia there were 12,264 newly diagnosed cases of upper respiratory tract cancer and 7562 relevant lethal cases. The authors provide data on such cancer incidence rate by site, groups of population, sex, age, type of tumor. Standardized incidence and mortality rates for various regions of Russia are indicative of the trend to the rates increase and relevant economic losses. The emphasis is on late diagnosis of ENT cancer, as 70-85% of the patients start anticancer treatment in advanced stages of the disease. This shows unsatisfactory situation in prehospital diagnosis of such tumors, numerous cases of misdiagnosis. The authors express their concern about poor oncological qualification of the practicing ENT specialists and urge improvements in current system of otorhinolaryngological training, performance of updated prophylactic and diagnostic measures.

Adolescent↗