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Altered behavioral responses to intense foot shock in socially-isolated rats.

Male Wistar rats were isolated immediately after weaning for 12 weeks and exposed to electric foot shock of various intensities. The shock-elicited jumping behavior was measured every ten minutes for one hr. The frequency of jumping in isolated rats was lower than that in grouped and the difference between two groups was the greatest with the most intense shock. In these experimental situations, there was no significant difference in monoamine turnover rate between the two groups while noradrenaline turnover markedly increased in both groups. Chlorpromazine suppressed the jumping in a dose-dependent manner in both groups with stronger suppression in isolated rats. Methamphetamine facilitated the jumping in grouped rats dose-dependently while the drug rather depressed it in the isolated. From these results and the behavioral similarity between the isolated and 6-hydroxydopamine treated rats under foot shock situation, it was suggested that the receptor supersensitivity of central catecholaminergic neurons was involved in the behavioral change in isolated rats.

Aggression

The effects of a modeling film on social isolation in preschool children: a methodological investigation.

Children in Headstart program (N=113) were assessed on two occasions using a naturalistic observation system and peer sociometric measures. Thirty-two children were selected by O'Connor's (1969, 1972) convergent criteria of teacher rankings and being below 15% peer interaction frequency. Half of the children saw an experimental modeling film designed to teach children how to initiate entry into peer groups and half of the children saw a control film. The present investigation included methodological elements left uncontrolled in previous investigations. Results indicated no significant multivariate F ratios for treatment main effects, sociometric main effects, or treatment by sociometric interactions. This failure to replicate previous results with the O'Connor film raises serious methodological criticisms of previous work with socially withdrawn children.

Behavior Therapy

Influence of sociality following isolation on feeding rhythms of monkeys entrained to artificial light schedules.

Socialization following a period of isolation disrupted the feeding rhythms of monkeys entrained to artificial light schedules. When isolation was reinstituted, the performances of the subjects, which had shifted during socialization, reverted to profiles similar to but not the same as they were in the initial isolation period. The strength of the social factor may have derived, in part, from the effects of the isolation which preceded the socialization phase.

Animals

Teaching social skills to isolated children.

The effects of a social skill training program on socially isolated children are reported. The training program was derived from the results of a previous study of the specific social skills that discriminated popular from unpopular children. Training effects in the present investigation were assessed on sociometric position, and on the quality, frequency, and distribution of social interaction to peers. Time-series analyses were performed on the frequency and distribution of peer interaction. Two isolated children received social skill training with an adult coach, and two isolated children spent an equivalent amount of time with an adult. Results indicated that socially isolated children in the treatment group changed significantly in sociometric position on a follow-up assessment 9 weeks after the end of the intervention, did not change in the total frequency of peer social interaction, but did redistribute their interaction to peers. The two isolated children who did not receive the treatment program did not change significantly on the total frequency of peer interaction, and tended to withdraw from peers rather than redistribute their interaction. The insensitivity of total peer interaction frequency as a measure of outcome was discussed.

Behavior Therapy

The problem of medical officer recruitment in agricultural industry.

All developing countries have difficulty in persuading doctors to opt for service in rural areas. This problem is shared by the agricultural industries. Two factors play a major role in this: isolation and the lack of a career structure. Isolation is an unavoidable accompaniment to rural practice. It can be considered as isolation from amenities, social isolation and professional isolation. The doctor in the rural area is often deprived of all urban amenities e.g. suitable shopping facilities, entertainment, cultural amenities and suitable leisure pursuits. Most of all, perhaps, he has major difficulties in educating his children. The maintenance of friendships and family connections is made difficult. There is a lack of suitable social intercourse for himself and his wife, a lack which very often leads to his wife's unhappiness and his own resignation. Professional isolation is serious and reflects adversely after a time on his professional ability. It may be that he only sees a colleague at long intervals and there is no stimulus towards keeping up to date professionally, and no opportunity to talk out professional and ethical problems. In many agricultural industries there is no career structure and therefore no scope for the good, ambitious doctor. This is particularly true of small, single-ownership plantations. It is clear that there is nothing to attract a good doctor to a place where he may remain at the same status for the rest of his professional career. It is suggested that only by the creation of a service structure within agricultural industries, which will create opportunities and within which means can be found to alleviate the effects of isolation, can a solution be found to the recruitment problem.

Agriculture

The relation between physical, psychological, and social morbidity in a suburban community.

Questionnaire scales of physical, psychological, and social morbidity were utilized to discover the relation between these indices in a representative Australian suburban sample of 863 adults aged 20-69 years. The physical and psychological morbidity of the sample was considerable and comparable to that revealed by other health surveys. There was a positive association between the occurrence of physical and psychological illness. The level of social isolation was low and in this residentially stable sample there was no association between social isolation and either physical or psychological morbidity.

Adult

Psychogeriatric hospital admissions from the community and institutions.

In a sample of 100 psychogeriatric admissions to three Toronto hospitals, the elderly in other institutions, including old age and nursing homes, and those living alone in the community were over-represented. Patients who had lived with relatives, on the other hand, were found to be at low risk for psychogeriatric hospitalization. These three groups of patients were compared using information obtained from psychiatric and social interviews with patients and informants, usually close relatives. Identification of specific needs for the various groups and the implication of these differences for the improvement of psychogeriatric care and prevention of unnecessary hospitalization are discussed. Institutional residents suffered more major physical illness, were less able to maintain functional independence, were referred more often for harmful behavior, were more socially isolated, and had a poorer outcome than community patients. Patients living along lacked familial support, but were not otherwise more socially isolated that those living with relatives, and showed no other deficits. The subjective and objective burdens on the patients' families before admission were considerable. The results are consistent with previous literature on the elderly.

Activities of Daily Living

A Systematic Review of Quantitative Studies of Depression and Loneliness in Black Women with Hypertension in the United States.

INTRODUCTION: Hypertension disproportionately affects Black women with subsequent complications that can extend beyond physical health. Notably, there is a significant relationship between hypertension, depression, and loneliness, with hypertensive Black women more likely to exhibit symptoms of depression. Since loneliness and social isolation are predictors of depression, recognizing and addressing these interconnected health concerns could improve patient outcomes and quality of life. This systematic review presents a synthesis of findings on depression screening practices, depression symptoms, and loneliness in quantitative studies of Black women with hypertension in the United States. METHODS: Using the EbscoHost platform, a comprehensive literature search for studies measuring depression and loneliness in Black women with hypertension was conducted. The following databases were selected: Medline Complete, CINAHL Complete, APA PsychArticles, and PsychINFO. RESULTS: Twenty-three articles were included; 16 focused on depression, and these studies highlighted a significant burden of depression in this demographic compared to their counterparts. Five studies reported loneliness and its relation to depression and hypertension. Loneliness and social isolation, as independent risk factors, exacerbated symptoms of depression and contributed to the onset and progression of hypertension. Two prior reviews corroborated these findings. Studies have emphasized the role of trust in clinical interactions and the importance of appropriate therapeutic interventions. DISCUSSION: Black women with hypertension are at a heightened risk for symptoms of depression, compounded by feelings of loneliness. Loneliness and depression are linked to physiological stress, contributing to hypertension. These problems are underrecognized and undertreated across populations, and this lack of recognition and treatment contributes to health inequity.

Humans

Social functioning and self-care in hospitalized psychogeriatric patients.

Evaluations of social disability have been found useful in determining factors of diagnostic, therapeutic and prognostic significance in the management of psychogeriatric patients. A random sample of 100 psychogeriatric patients aged 65 or over admitted to three Toronto hospitals were studied prospectively. Standardized clinical and social interview schedules were used to assess patients' mental state, self-care capacity, social isolation, burden on the family and household contribution before admission. These assessments were carried out to determine their significance with respect to diagnosis and outcome. Self-care capacity, as measured by the Activities of Daily Living Performance Test or by informant report, was related to diagnosis and outcome measures in this sample. Social isolation was significantly correlated with length of hospital stay. Burden on the family was not found to be significantly associated with diagnosis or outcome although there was a tendency for patients with organic disorders to present more difficulties for their families. The severe burden imposed on relatives suggests the need for utilization of community social and medical services to provide relief for families of psychogeriatric patients. The implications for management are considered in the light of the above findings.

Activities of Daily Living

Environmentally induced differences in susceptibility of rats to CNS stimulants and CNS depressants: evidence against a unitary explanation.

It has been suggested that socially isolated rats are more aroused then rats raised in social groups. This hypothesis was tested by examining amphetamine-induced activity and stereotypy in social and isolated rats of both sexes in both the active and inactive phases of their diurnal activity cycle. In socially raised rats it was possible to produce behavioural profiles similar to those of isolated rats by increasing the arousal level of the social rat. However, the complex interaction of housing conditions, diurnal variation and gender with drug dose suggests that one intervening variable such as arousal is too simplistic an explanation. In subsequent experiments, stereotypy was enhanced by a familiar environment, and there was a clear dissociation between the effects of CNS stimulants and CNS depressants. The increased susceptibility of isolates to CNS stimulants depends on social isolation for a short period before 45 days of age; the decreased susceptibility of isolates to CNS depressants may be produced by isolation at any age. We conclude that there is no evidence that isolated rats are hyperaroused.

Animals

The social behavior of elderly aphasic versus nonaphasic long-term patients.

A study was made of the social consequences of communicative disorders among 51 elderly hospitalized long-term patients. Independent variables used to account for variations in social behavior were: 1) the presence or absence of aphasia, an impairment resulting in varying degrees of loss of verbal recognition, comprehension and language production; 2) sex; and 3) the level of nursing-care needs as an indicator of overall physical independence. A rating scale for measuring "Social Involvement" was constructed. It involved four analytically-derived factors - Interpersonal Behavior, Familial and Social Contacts, Group Participation, and Extent of Social Contacts. Since a comparison of the 15 aphasic and 36 nonaphasic subjects on the basis of these four factors revealed no substantial main effect, it would seem that social isolation was not attributable to aphasia per se. Rather, a number of significant interactions indicated that differences in the levels of social involvement were attributable to the combined influences of sex, presence or absence of aphasia, and varying levels of physical independence. The relationship between social involvement and social isolation has implications for the overall management and rehibilitation of long-term patients.

Aged

The biology of social attachments: opiates alleviate separation distress.

The possibility that brain opiate systems participate in the control of social affect was assessed by determining capacity of low doses of exogenous opiates (0.125-0.50 mg/kg oxymorphone, and 0.10-0.50 mg/kg morphine sulfate) to reduce distress vocalizations of socially isolated puppies. Low doses of opiates were capable of profoundly reducing crying as well as the motor agitation they exhibit during brief periods of social isolation. Since reductions in crying could be obtained with morphine in the absence of any gross behavioral disturbances, the possibility is entertained that brain opiates may function to control the intensity of emotions arising from social separation. Possible parallels between the biological nature of narcotic addiction and the formation of social bonds are discussed.

Animals