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PubMed1996

[Hepatic tuberculosis: a report of 8 patients].

8 patients with hepatic tuberculosis were confirmed by surgical operation and pathological examination of liver. The average age of the patients was 26.5 years. Only one of the 8 patients was suspected of having hepatic tuberculosis before operation. Liver biopsy during the operation was carried out in 3 patients, and lobectomy or partial excision of the liver was performed in 4 patients, and incision and drainage of the liver abscess were performed in 1 patient. All of the patients were cured. The follow-up results showed that hepatic tuberculosis less than or equals to 3 cm in diameter could be cured by regular chemotherapeutics. In this paper, the infectious path, pathological types, differential diagnosis and treatment are discussed, and experience and lessons are summarized.

Adolescent↗
PubMedDate not supplied

[Macronodular hepatic tuberculosis. Echographic diagnosis of 2 cases].

Two cases of macronodular hepatic tuberculosis are reported. In both cases primary or metastatic liver tumor had been suspected Hepatic tuberculosis was diagnosed by ultrasonically guided percutaneous fine-needle biopsy. Percutaneous needle biopsy of the liver appears to be a safe and valuable procedure for differentiating systemic or infiltrative diseases such as tuberculosis from primary or metastatic liver tumor.

Aged↗
PubMedDate not supplied

Hepatic tuberculosis presenting as cholestatic jaundice. A case report.

We report three cases of hepatic tuberculosis with cholestatic jaundice. All three patients presented with cholestatic jaundice, anorexia, fever and weight loss. All had hepatomegaly. No biliary obstruction was detected. Two patients had evidence of extra hepatic tuberculosis but one had no such evidence. Diagnosis of hepatic tuberculosis was confirmed by liver biopsy. Little is known about tuberculous affecting the liver and the general belief is that it is a histopathological entity only, but these cases are a reminder of the unusual manifestation of a very common condition. All the cases recovered with anti-tuberculous treatment.

Adult↗
PubMed2005

Hypercalcemia in hepatic tuberculosis: a case report in Korea.

Although primary hyperparathyroidism and malignant diseases account for approximately 90% of the causes of hypercalcemia, they could occur in association with granulomatous diseases such as tuberculosis or sarcoidosis, especially in developing countries. Hepatic tuberculosis is difficult to diagnosis without suspicion in cases with normal findings on chest radiographs. We report a 70-year-old woman who presented with hypercalcemia due to hepatic tuberculosis. The diagnosis was made by a computed tomography scan and laparoscopic evaluation. After treatment with anti-tuberculosis medication, her hypercalcemia resolved. Increased vitamin D synthesis by activated macrophages in the granuloma tissue is the major mechanism of hypercalcemia in tuberculosis.

Aged↗
PubMedDate not supplied

[Hepatic tuberculosis in a patient with diabetic nephropathy. An unusual clinical presentation].

Hepatic tuberculosis is an exceptional form of presentation of extrapulmonary tuberculosis, but in the last years a greater incidence has been found in patients with HIV infection and/or consumptive diseases or immunosuppressive treatment. For this condition, the diagnosis of hepatic tuberculosis in other population groups represents a true clinical challenge because of the scarce specificity of both the clinical and biological manifestations. Despite deferral of the diagnosis, fast improvement is observed in the clinical symptomatology in most cases following initiation of tuberculostatic treatment.

Diabetic Nephropathies↗
PubMedDate not supplied

Hepatic tuberculosis in absence of disseminated abdominal tuberculosis.

Liver involvement in tuberculosis in absence of miliary tuberculosis is rare. This study was performed to analyse the spectrum and response to treatment of hepatic tuberculosis in the absence of miliary abdominal tuberculosis. Retrospective analysis of seven cases of hepatic tuberculosis without miliary abdominal tuberculosis who presented at the single tertiary referral center were analyzed. All patients presented with fever and hepatomegaly. Five of them had pain in upper abdomen and vomiting. HIV serology was positive in one patient. All patients had normocytic normochromic anaemia, raised erythrocyte sedimentation rate (Mean 65). Mild elevation of liver enzymes and low albumin (Mean 2.4 gm%) with reversal of albumin globulin ratio (Mean 0.6) were seen in all. Two had jaundice. Prothrombin time was normal in all and lactate dehydrogenase values were elevated in all (Mean 794 IU/L). On ultrasonography, 2 had multiple hypodense lesion, 1 had coarse echotexture of liver, 1 had hyperechoic pattern and 3 had just hepatomegaly. Complete resolution of liver lesions on treatment with 4-drug anti-tuberculosis drug chemotherapy was seen. In conclusion, liver tuberculosis has protean manifestations with nonspecific alteration of liver function tests and is best diagnosed on liver biopsy. Overall response to therapy is satisfactory.

Adolescent↗
PubMed1992

Pseudotumoral hepatic tuberculosis. Atypical presentation and comprehensive review of the literature.

We describe a 40-year-old black North American woman with isolated hepatic tuberculosis and an incidentally elevated alkaline phosphatase. Imaging studies of the liver showed a lesion suggesting primary or metastatic disease, which turned out to be the so-called pseudotumoral form of hepatic tuberculosis. We believe this is the first case recorded in the English language literature of isolated hepatic tuberculosis manifesting first as an incidentally elevated alkaline phosphatase. It seems to be the third documented case in the English literature of a patient with this rare form of tuberculous involvement without systemic manifestations. The patient responded to antituberculous therapy and is healthy 4 years after treatment.

Biopsy, Needle↗