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Results for “Wound Infection”

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At least 37 records · Page 2Linked to original sources
PubMed1978

Wound infection in emergency appendicectomy: a prospective trial with tropical ampicillin and antiseptic solution irrigation.

A randomized controlled trial in 374 patients requiring emergency appendicectomy to determine the value of topical ampicillin and an antiseptic solution of chlorhexidine and cetyl trimethyl ammonium bromide (Savlon) in preventing wound infection is reported. The application of 1 g of ampicillin powder to the wound significantly reduced wound infection in perforated appendicitis, but not in unperforated appendicitis. Wound irrigation with 1% cetyl trimethyl ammonium bromide was ineffective in preventing wound infection in all grades of appendicitis. When wound contamination is difficult to avoid, as in perforated appendicitis, topical ampicillin should be used to reduce the rate of wound infection.

Administration, Topical↗
PubMedDate not supplied

Vibrio alginolyticus wound infection: case report and review.

Vibrio alginolyticus was associated with a littoral wound infection in an Arizonan injured near the Sea of Cortez. While this is the first instance from this estuary, the relatively recent increase in the number of isolates suggests both that most coastal waters are a natural habitat of the organism and that probably many previous isolates were incorrectly identified in the past. Mischaracterization most likely results from a gram-negative work-up routine deficient for the isolation of halophilic organisms. The morbid course of this case was in part predictable owing to the organism's resistance to several first choice antibiotics. The laboratory characteristics of V. alginolyticus and others in the Vibrio genus associated with maritime disease are reviewed.

Adult↗
PubMed1978

The effect of metronidazole on the incidence of postoperative wound infection in elective colon surgery.

A prospective randomized clinical trial assessing the relative effectiveness of erythromycin-neomycin and metronidazole-neomycin as a preoperative bowel preparation was carried out. Bacteriologic studies of feces and colon content revealed no significant difference in the reduction of aerobic bacteria between the two groups. There was, however, a significantly greater reduction in anaerobic bacteria in the feces and colon contents of patients receiving metronidazole. Wound infection rate was 25% in the erythromycin group, and organisms recovered from the wound in all cases were fecal in nature. Two wound infections occurred in the metronidazole group (5%) and in both cases the organisms recovered were staphylococci of presumed skin origin. These studies suggest that anaerobic bacteria are the major contributors to wound infection after colon surgery and that their specific reduction is associated with a lower incidence of wound infection.

Bacteroides↗
PubMed1977

Postoperative chest wound infections in patients requiring coronary bypass. A controlled study evaluating prophylactic antibiotics.

A controlled study investigating clean chest wound infections in 904 patients undergoing myocardial revascularization was performed. Four hundred fifty-one patients received systemic antibiotics before and after the operation, and 453 patients received no prophylactic systemic antibiotics. The infection rate was 1.10 per cent and 1.76 per cent, respectively, indicating no statistical difference between the two groups. Preoperative skin preparation and subsequent local antibiotic wound irrigation may be the most important factors in preventing clean wound infection.

Aged↗
PubMed1979

Effect of postoperative wound infection on the course of stage II melanoma.

Microbial infections reportedly have a favorable effect on the course of certain malignant diseases. Intralesional inoculation of micro-organisms can bring about tumor regression in certain clinical and experimental situations. In order to evaluate the influence of immediate postoperative wound infection on the course of Stage II melanomas, a retrospective study was undertaken of 211 patients who had undergone axillary or groin dissection. None had any antibiotic, steroid, chemoimmunotherapy, or cryosurgery and there was no history of a second primary neoplasm, pregnancy, immunodeficiency, or administration of immunosuppressive drugs. Forty of these patients developed significant postoperative wound infections. Although their representation according to sex, tumor location, number of nodes involved, and other parameters was comparable to that of the remaining 171 patients who did not develop wound infections, the incidence of local recurrence in the group with infections was significantly lower (p less than 0.01). Patient survival and disease-free interval following node dissection were not influenced by infection. Postoperative infections in the groin or axilla offered only local protection from tumor recurrence; the ultimate course of the disease was not affected.

Escherichia coli Infections↗
PubMed1979

Contamination with enterobacteria and postoperative wound infection after appendicectomy.

The impact of contamination on wound infections was investigated in 120 patients undergoing appendicectomy for appendicitis. A quantitative sample for culture of enterobacteria was obtained from the subcutaneous wound with the velvet pad imprint technique. Average number of enterobacteria (CFU) in the would was 1.2 logarithms higher in operations for gangrenous appendices and 2.3 logarithms higher in perforated appendices compared to flegmonous appendices. Infection rate was 2.5% in flegmonous, 10% in gangrenous and 27.5% in perforated appendices. The results focus the close relation between contamination and subsequent infection.

Appendectomy↗
PubMed1977

Prevention of wound infection in abdominal operations by peroperative antibiotics or povidone-iodine. A controlled trial.

The wound-infection rate after abdominal operations was compared in 113 patients randomly allocated to an untreated control group, a group receiving preoperative lincomycin and tobramycin, or a group receiving local instillation of povidone-iodine. The wound-infection rate was 8.1% in 37 patients receiving antibiotics, 42.1% in 38 untreated controls, and 39.5% in 38 patients in the povidone-iodine group.

Abdomen↗
PubMed1978

The clinical importance of anaerobic bacteria in wound infections after gastrointestinal surgery.

Wound cultures from 54 patients with infections after gastrointestinal surgery were examined. Cultures from wounds after surgery on the upper gastrointestinal tract grew few organisms, mainly aerobic gram-positive cocci. Culture from wounds on the lower gastrointestinal tract grew strains of bacteria, aerobic and anaerobic gram-negative rods dominating. Indirect immunofluorescence studies on acute and convalescent phase sera showed significant immune response against Bacteroides fragilis in a majority of cases. Immune response against anaerobic cocci was seldom found. Very high antibody titres against Clostridium perfringens were often found, both in patients' and control sera.

Adolescent↗
PubMed1978

An epidemiologic study of postoperative staphylococcal wound infections in patients having vascular procedures.

An epidemic of postoperative wound infections caused by Staphylococcus aureus in 15 patients during a four-month period in 1974 is reported. An unusual staphylococcal antibiogram served as a marker for the multiresistant strain of hospital-acquired infections and raised suspicion of a common source for the infections. The spread of infection began shortly after isolation was discontinued in the index case. An epidemiologic investigation showed that 14 patients were on the same ward, and one patient from another ward had opportunity for contact with the index case. The epidemic was controlled by prompt isolation of all infected patients, adherence to strict isolation techniques, aseptic technique for dressing changes and by treatment of nasal carriers among ward personnel with appropriate antibiotics.

Anti-Bacterial Agents↗